Article
Oncology
Yunfei Yan, Yu Wang, Na Liu, Yuansheng Duan, Xiaohan Chen, Beibei Ye, Rong Yang, Wenchao Zhang, Xudong Wang
Summary: DLNM serves as a predictive indicator for cervical lymph node metastasis in PTC patients, highlighting the importance of DLN detection in guiding the extent of surgery.
Article
Oncology
Vaishali Jain, Javed Akhtar, Ratna Priya, Puja Sakhuja, Surbhi Goyal, Anil Kumar Agarwal, Vivek Ghose, Ravindra Varma Polisetty, Ravi Sirdeshmukh, Fouzia Siraj, Poonam Gautam
Summary: This study identified proteins associated with lymph node metastasis in gallbladder cancer, which may be further explored for diagnostics and therapeutics in lymph node positive cases.
Review
Oncology
Yuhang Li, Yinghui Song, Yujing Zhang, Sulai Liu
Summary: This article discusses the lymph node pathways, metastatic directions, and treatment methods for gallbladder cancer, emphasizing the importance of developing individualized treatments for predicting the prognosis of patients with different lymph node conditions.
FRONTIERS IN ONCOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
J. J. Wu, L. W. Ma, C. H. Jiang, J. Chen, N. Li, X. Q. Chen, A. J. Min, W. J. Wang, Y. Q. Hu, X. Gao
Summary: This study aims to evaluate the rare postoperative supraclavicular metastasis originating from oral squamous cell carcinoma (OSCC) and discuss the potential predictive marker of epidermal growth factor receptor (EGFR). The findings suggest that supraclavicular metastasis of OSCC is infrequent and associated with a poor prognosis, and EGFR might predict the occurrence of supraclavicular metastasis.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2022)
Article
Otorhinolaryngology
Wenwu Dong, Kiyomi Horiuchi, Eiichiro Noguchi, Takahiro Okamoto
Summary: Patients with palpable lymph nodes have a higher risk of recurrence compared to those with nonpalpable lymph nodes; for patients with palpable lymph nodes, lateral lymph node ratio >= 0.5 and age >= 55 years are independent prognostic factors; for those without palpable nodes, age >= 55 years and tumor size >4 cm are independently predictive of worse RFS.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Article
Biochemistry & Molecular Biology
Young-Jae Ryu, Seong-Young Kwon, Soo-Young Lim, Yong-Min Na, Min-Ho Park
Summary: This study aimed to evaluate the predictive factors of skip metastases in pN1b papillary thyroid carcinoma (PTC) patients and their impact on recurrence. The results showed that tumor size <= 1 cm was an important predictive factor for skip metastases, while stimulated thyroglobulin (Tg) level was a strong predictor of recurrence.
Article
Endocrinology & Metabolism
Zipeng Wang, Qungang Chang, Hanyin Zhang, Gongbo Du, Shuo Li, Yihao Liu, Hanlin Sun, Detao Yin
Summary: This study aimed to explore the risk factors and develop a predictive model for central lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC). The analysis of collected data revealed that age, gender, multifocality, BRAF, and tumor size were associated with CLNM. The predictive model was shown to be practical and convenient for clinicians to predict CLNM in PTC.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Oncology
Qiao Hu, Wang-Jian Zhang, Li Liang, Ling-Ling Li, Wu Yin, Quan-Li Su, Fei-Fei Lin
Summary: This study established a nomogram to predict cervical lymph node metastasis in patients with papillary thyroid carcinoma. Male gender, age <45 years, tumor size >20mm, multifocality, ambiguous boundary, extracapsular invasion, and ultrasound-suggested lymph node metastasis were identified as independent risk factors for CLNM.
FRONTIERS IN ONCOLOGY
(2022)
Article
Endocrinology & Metabolism
Juerong Lu, Jintang Liao, Yunhao Chen, Jie Li, Xinyue Huang, Huajun Zhang, Bo Zhang
Summary: By analyzing ultrasound characteristics and clinical data, we identified clinical factors associated with lymph node metastasis in patients with papillary thyroid carcinoma (PTC), and developed a personalized nomogram for predicting lymph node metastasis. The nomogram showed excellent discrimination, calibration, and clinical practicability, and may assist clinicians in predicting lymph node metastasis prior to surgery.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Oncology
Xingdan Guo, Chunhua Lin, Jing Zhao, Mi Tang
Summary: The histological grade of endometrial endometrioid carcinoma (EEC) is found to be an important factor in lymph node metastasis (LNM). In this study, researchers developed a novel nomogram model for predicting LNM in patients with endometrioid carcinoma (EC), which could potentially assist surgeons in making optimal treatment decisions.
Article
Oncology
Kevin L. Ma, Cimarron E. Sharon, Gabriella N. Tortorello, Nikhita J. Perry, Luke J. Keele, John N. Lukens, Giorgos C. Karakousis, John T. Miura
Summary: This retrospective cohort study analyzed data from the National Cancer Database from 2012 to 2019. The study found that there was no significant difference in survival benefits between radiation therapy and completion lymph node dissection for regional lymph node micrometastasis in Merkel cell carcinoma (MCC) patients.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Il Ku Kang, Joonseon Park, Ja Seong Bae, Jeong Soo Kim, Kwangsoon Kim
Summary: The American Thyroid Association risk stratification system indicates that having more than 5 metastatic lymph nodes (LNs) increases the risk of recurrence in patients with papillary thyroid carcinoma (PTC). This study aimed to stratify PTC patients with fewer than 5 harvested LNs based on lymph node ratios (LNRs). The results showed that LNR can be used to stratify the risk of recurrence in patients with low-LNY PTC.
Article
Endocrinology & Metabolism
Yu Min, Yizhou Huang, Minjie Wei, Xiaoyuan Wei, Hang Chen, Xing Wang, Jialin Chen, Ke Xiang, Yang Feng, Guobing Yin
Summary: High serum thyroglobulin antibody (TgAb) level, lower tumor location, irregular margin of CLN, and micro-calcification in the CLN were significantly associated with CLN metastasis in PTC patients with HT. An individualized nomogram with a favorable C-index of 0.815 was established, which may help surgeons manage the CLN in this subpopulation.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Yijie Huang, Ying Yin, Wenyi Zhou
Summary: PTMC patients have a significant incidence of lymph node metastases. Risk factors for CLNM include age, gender, and tumor size, while extrathyroidal extension and number of CLNM are strong indicators for LLNM. Identifying these factors can help tailor individual surgical interventions for PTMC patients.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Urology & Nephrology
Nicholas H. Chakiryan, Aaron Dahmen, Marco Bandini, Filippo Pederzoli, Laura Marandino, Maarten Albersen, Eduard Roussel, Yao Zhu, Ding-Wei Ye, Antonio A. Ornellas, Mario Catanzaro, Oliver W. Hakenberg, Axel Heidenreich, Friederike Haidl, Nick Watkin, Michael Ager, Jad Chahoud, Alberto Briganti, Roberto Salvioni, Francesco Montorsi, Andrea Necchi, Philippe E. Spiess
Summary: This study found that 31.9% of pSCC patients experienced post-ILND recurrence, which was associated with high pN staging. Over 95% of distant, inguinal, and pelvic recurrences occurred within 48 months post-ILND. Local recurrences occurred over a longer timeline, highlighting the necessity of long-term surveillance of the primary site.
JOURNAL OF UROLOGY
(2021)