Oral caffeine administration ameliorates acute colitis by suppressing chitinase 3-like 1 expression in intestinal epithelial cells

Ulcerative colitis

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Role of YKL-40 in Bronchial Smooth Muscle Remodeling in Asthma

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Update on biologic pathways in inflammatory bowel disease and their therapeutic relevance

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Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Caffeine for treatment of Parkinson disease: A randomized controlled trial

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Chitinase 3-Like-1 Expression in Colonic Epithelial Cells as a Potentially Novel Marker for Colitis-Associated Neoplasia

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Carbohydrate-binding motif in chitinase 3-like 1 (CHI3L1/YKL-40) specifically activates Akt signaling pathway in colonic epithelial cells

(2011) Chun-Chuan Chen et al.   CLINICAL IMMUNOLOGY

Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells

(2011) Bo Mi Ku et al.   MOLECULES AND CELLS

Caffeine in Parkinson's disease: A pilot open-label, dose-escalation study

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Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

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Proctocolitis Caused by Coffee Enemas

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Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

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Potential role of chitinase 3-like-1 in inflammationassociated carcinogenic changes of epithelial cells

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Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

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