The inflammatory network in the gastrointestinal tumor microenvironment: lessons from mouse models

The Unholy Trinity: Inflammation, Cytokines, and STAT3 Shape The Cancer Microenvironment

(2011) Ning Li et al.   CANCER CELL

Selective PGE2 Suppression Inhibits Colon Carcinogenesis and Modifies Local Mucosal Immunity

(2011) M. Nakanishi et al.   Cancer Prevention Research

Activation of epidermal growth factor receptor signaling by the prostaglandin E2 receptor EP4 pathway during gastric tumorigenesis

(2011) Hiroko Oshima et al.   CANCER SCIENCE

COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+ mouse polyps

(2011) Y. Nakanishi et al.   CARCINOGENESIS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Tobacco Smoke Promotes Lung Tumorigenesis by Triggering IKKβ- and JNK1-Dependent Inflammation

(2010) Hiroyuki Takahashi et al.   CANCER CELL

Tumor formation in a mouse model of colitis-associated colon cancer does not require COX-1 or COX-2 expression

(2010) T. o. Ishikawa et al.   CARCINOGENESIS

Cox-2 deletion in myeloid and endothelial cells, but not in epithelial cells, exacerbates murine colitis.

(2010) T.-o. Ishikawa et al.   CARCINOGENESIS

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

(2010) Eek Joong Park et al.   CELL

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

NF-κB and STAT3 – key players in liver inflammation and cancer

(2010) Guobin He et al.   CELL RESEARCH

Prostaglandin E2 Signaling and Bacterial Infection Recruit Tumor-Promoting Macrophages to Mouse Gastric Tumors

(2010) Hiroko Oshima et al.   GASTROENTEROLOGY

ERK activation drives intestinal tumorigenesis in Apcmin/+ mice

(2010) Sung Hee Lee et al.   NATURE MEDICINE

Mouse models of gastric tumors: Wnt activation and PGE2 induction

(2010) Hiroko Oshima et al.   PATHOLOGY INTERNATIONAL

Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis

(2010) W.-J. Chae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages

(2009) David G. DeNardo et al.   CANCER CELL

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

(2009) Julia Bollrath et al.   CANCER CELL

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

Polyps Wrap Mast Cells and Treg within Tumorigenic Tentacles

(2009) M. P. Colombo et al.   CANCER RESEARCH

Blockade of a Chemokine, CCL2, Reduces Chronic Colitis-Associated Carcinogenesis in Mice

(2009) B. K. Popivanova et al.   CANCER RESEARCH

T-Regulatory Cells Shift from a Protective Anti-Inflammatory to a Cancer-Promoting Proinflammatory Phenotype in Polyposis

(2009) Elias Gounaris et al.   CANCER RESEARCH

Prostaglandin E2, Wnt, and BMP in gastric tumor mouse models

(2009) Hiroko Oshima et al.   CANCER SCIENCE

Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe

(2009) B. B. Aggarwal et al.   CLINICAL CANCER RESEARCH

Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors

(2009) Masayuki Fukata et al.   INFLAMMATORY BOWEL DISEASES

The role of COX-2 in intestinal inflammation and colorectal cancer

(2009) D Wang et al.   ONCOGENE

Transgenic expression of cyclooxygenase-2 in mouse intestine epithelium is insufficient to initiate tumorigenesis but promotes tumor progression

(2008) Mazin A. Al-Salihi et al.   CANCER LETTERS

Genetic Deletion of mPGES-1 Suppresses Intestinal Tumorigenesis

(2008) M. Nakanishi et al.   CANCER RESEARCH

Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells

(2008) Keisuke Oguma et al.   EMBO JOURNAL

Systematic review of the association between circulating interleukin-6 (IL-6) and cancer

(2008) Katriina Heikkilä et al.   EUROPEAN JOURNAL OF CANCER

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE