Article
Medicine, General & Internal
Yuri Sakamoto, Yohei Takeda, Yuta Seki, Shiho Kawahara, Takuya Shimosaka, Wataru Hamamoto, Hiroki Koda, Taro Yamashita, Takumi Onoyama, Kazuya Matsumoto, Kazuo Yashima, Hajime Isomoto
Summary: Peroral Cholangioscopy (POCS) is effective in achieving complete stone removal for intrahepatic stones, but it is associated with a longer procedure time compared to fluoroscopic guidance. However, the incidence of cholangitis was not significantly different between patients with and without POCS. This study highlights the importance of specialized equipment and experienced staff for endoscopic treatment of intrahepatic stones.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Surgery
Hirokazu Saito, Hajime Iwasaki, Hisashi Itoshima, Yoshihiro Kadono, Takashi Shono, Kentaro Kamikawa, Masayoshi Uehara, Atsushi Urata, Jiro Nasu, Ikuo Matsushita, Tatsuyuki Kakuma, Shuji Tada
Summary: This study aimed to examine the cumulative diagnosis rate and the predictive factors of spontaneous CBDS passage during the interval between imaging diagnosis and ERCP. The study found that CBDS sized < 6 mm on diagnostic imaging, solitary CBDS, intervals between the imaging diagnosis and ERCP, and nondilated common bile duct (< 10 mm) were significant factors associated with spontaneous CBDS passage. Therefore, preliminary endoscopic ultrasonography immediately before ERCP is recommended, especially in patients with solitary and small CBDSs on diagnostic imaging.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Surgery
Jisheng Zhu, Guoyong Li, Peng Du, Xin Zhou, Weidong Xiao, Yong Li
Summary: The study compared the efficacy and safety of LCBDE + LC with IO-ERCP + LC for the treatment of gallbladder and CBD stones, finding no significant difference in technical success, morbidity, major morbidity, and conversion rate. However, LCBDE + LC had a higher biliary leak rate, lower postoperative pancreatitis rate, and higher rate of retained stones compared to IO-ERCP + LC.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Medicine, General & Internal
Koji Takahashi, Hiroshi Ohyama, Yuichi Takiguchi, Yu Sekine, Shodai Toyama, Nana Yamada, Chihei Sugihara, Motoyasu Kan, Mayu Ouchi, Hiroki Nagashima, Yotaro Iino, Yuko Kusakabe, Kohichiroh Okitsu, Izumi Ohno, Naoya Kato
Summary: This study aimed to investigate the efficacy and safety of EHL using peroral cholangioscopy (POCS) under endoscopic retrograde cholangiopancreatography (ERCP) guidance in older adults aged >= 80 years. The results showed that complete removal of common bile duct stones was achieved in 93.8% and 100% of elderly and non-elderly groups, respectively. The occurrence of adverse events during the EHL session did not significantly differ between the two groups.
MEDICINA-LITHUANIA
(2023)
Review
Medicine, General & Internal
Kun Wu, Linking Xiao, Jifeng Xiang, Lu Huan, Wei Xie
Summary: This study compared different timings of laparoscopic cholecystectomy (LC) after endoscopic retrograde cholangiopancreatography (ERCP). The results suggested that LC performed within 24 to 72 hours after ERCP had advantages in terms of conversion rate and no recurrence of acute cholecystitis episodes.
Article
Health Care Sciences & Services
Sheng-Fu Wang, Chi-Huan Wu, Kai-Feng Sung, Yung-Kuan Tsou, Cheng-Hui Lin, Chao-Wei Lee, Mu-Hsien Lee, Nai-Jen Liu
Summary: This study aimed to investigate the impact of serum lipid level on the recurrence of stones after endoscopic sphincterotomy followed by cholecystectomy. The results showed that a higher serum HDL level, lower total cholesterol level, and the use of statins can reduce the risk of stone recurrence.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Surgery
Caining Lei, Tingting Lu, Wenwen Yang, Man Yang, Hongwei Tian, Shaoming Song, Shiyi Gong, Jia Yang, Wenjie Jiang, Kehu Yang, Tiankang Guo
Summary: In comparing LC-IntraERCP and LC-LCBDE, there were no significant differences in terms of surgical success rate, overall postoperative complications, conversion to laparotomy, and operative time. However, LC-IntraERCP may be more effective in reducing the rate of retained stones.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Il Sang Shin, Jong Ho Moon, Yun Nah Lee, Hee Kyung Kim, Jun Chul Chung, Tae Hoon Lee, Jae Kook Yang, Sang-Woo Cha, Young Deok Cho, Sang-Heum Park
Summary: We developed a feasible endoscopic classification system based on peroral cholangioscopy (POC) findings for intraductal neoplasm of the bile duct (IN-B). POC with narrow-band imaging (NBI) was found to be useful for detecting IN-Bs. Our novel classification system, which considers both surface structure and microvascular pattern, allows differentiation of IN-B from intraductal superficial lesions of the bile duct (ISL-Bs). Rating: 8 out of 10.
GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Hirokazu Saito, Hajime Iwasaki, Hisashi Itoshima, Yoshihiro Kadono, Takashi Shono, Kentaro Kamikawa, Atsushi Urata, Jiro Nasu, Masayoshi Uehara, Ikuo Matsushita, Tatsuyuki Kakuma, Shuji Tada
Summary: High-risk patients with suspected common bile duct stones (CBDSs) based on the revised ASGE guideline 2019 have a high detection rate of CBDS during endoscopic retrograde cholangiopancreatography (ERCP). However, performing ERCP on patients with only clinical predictors often results in unnecessary procedures.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Medicine, General & Internal
Liang Zhu, Zhi-Quan Huang, Zhen-Wen Wang, Xue-Ping Yang, Jun-Bo Hong, Zhen-Zhen Yang, Zheng-Ping Yu, Rong-Lai Cao, Jin-Li He, You-Xiang Chen
Summary: This study compared the diagnostic value of cytobrush, ERCP-guided biopsy, SpyGlass direct visual impression, and SpyGlass-guided biopsy (SpyBite) in differentiating between benign and malignant bile duct strictures. The results showed that SpyBite combined with SpyGlass-guided visual impression had higher sensitivity and accuracy compared to conventional endoscopic diagnostic methods such as cytobrush and standard biopsy.
FRONTIERS IN MEDICINE
(2023)
Review
Medicine, General & Internal
Natalia Valeria Pentara, Aristidis Ioannidis, Georgios Tzikos, Leonidas Kougias, Eleni Karlafti, Angeliki Chorti, Despoina Tsalkatidou, Antonios Michalopoulos, Daniel Paramythiotis
Summary: This article describes a rare case of biloma as a complication of endoscopic retrograde cholangiopancreatography (ERCP). The patient experienced right upper quadrant discomfort after the procedure and imaging confirmed the presence of biloma. The article highlights the importance of considering biliary tree disruption in patients with right upper quadrant discomfort following an iatrogenic or traumatic event, and suggests that a combination of radiological imaging and minimal invasive techniques can be successful in managing biloma.
Article
Gastroenterology & Hepatology
Wisam Sbeit, Anas Kadah, Matta Simaan, Amir Shahin, Tawfik Khoury
Summary: This study identified risk factors for recurrent common bile duct (CBD) stone, including mechanical lithotripsy, method of stone extraction, and age. Considering these factors may help minimize the risk of recurrent CBD stone.
HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL
(2022)
Article
Gastroenterology & Hepatology
Yaping Guan, Encheng Zhang, Cheng Zhang, Zhihan Ye, Feng Zhu
Summary: This study aimed to explore the alteration of bile acid profiles in patients with choledocholithiasis (CDC) and construct a prediction model for evaluating the risk of common bile duct stone (CBDS) recurrence after endoscopic treatment. The study found that the serum BA profiles were different in patients with CDC compared to controls, and a diagnostic model was successfully developed to distinguish patients with CDC from controls. The developed nomogram model for predicting the risk of CBDS recurrence had high accuracy and clinical usability.
JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
(2023)
Article
Pharmacology & Pharmacy
W. -F. Lan, J. -H. LI, Q. -B. Wang, X. -P. Zhan, W. -L. Yang, L. -T. Wang, K. -Z. Tang
Summary: This study compared the effectiveness and safety of laparoscopic common bile duct exploration (LCBDE) and endoscopic retrograde cholangiopancreatography (ERCP) combined with laparoscopic cholecystectomy (LC) for treating gallbladder and common bile duct stones. The results showed no significant difference in treatment outcomes between LCBDE and ERCP. However, LCBDE had a higher rate of bile leakage and a lower rate of postoperative pancreatitis, cholangitis, and hemorrhage.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Article
Medicine, General & Internal
Chi-Young Jeong, Jung Woo Choi, Jae-Ri Kim, Jae Yool Jang, Jin-Kyu Cho
Summary: Therapeutic laparoscopic-assisted transgastric endoscopic retrograde cholangiopancreatography (LA-ERCP) is a safe and effective technique for managing bile duct complications. A patient with acute calculous cholecystitis and acute cholangitis was successfully treated with laparoscopic cholecystectomy and biliary stent insertion.
Review
Gastroenterology & Hepatology
Takuji Iwashita, Shinya Uemura, Ryuichi Tezuka, Akihiko Senju, Ichiro Yasuda, Masahito Shimizu
Summary: Endoscopic ultrasound-guided antegrade intervention (EUS-AG) has been reported as a useful management method for biliary diseases in patients with surgically altered anatomy.
DIGESTIVE ENDOSCOPY
(2023)
Article
Oncology
Nozomu Muraishi, Yusuke Kawamura, Norio Akuta, Junichi Shindoh, Masaru Matsumura, Satoshi Okubo, Shunichiro Fujiyama, Tetsuya Hosaka, Satoshi Saitoh, Hitomi Sezaki, Fumitaka Suzuki, Yoshiyuki Suzuki, Kenji Ikeda, Yasuji Arase, Masaji Hashimoto, Ichiro Yasuda, Hiromitsu Kumada
Summary: In this study, the effect of lenvatinib on tumor blood vessel diameter in patients with hepatocellular carcinoma was investigated. It was found that lenvatinib can reduce the diameter of tumor blood vessels, which may be considered as a process of normalization. The decrease in tumor blood vessels in imaging analysis may be associated with improved prognosis, but further studies are still required.
Article
Oncology
Takayuki Ando, Ayumu Hosokawa, Miho Sakumura, Iori Motoo, Shinya Kajiura, Katsuhisa Hirano, Takeshi Miwa, Tomotaka Yokota, Naokatsu Nakada, Yuko Ueda, Akira Ueda, Kenichiro Tsukada, Kohei Ogawa, Atsuko Nakaya, Akira Teramoto, Sohachi Nanjo, Hiroshi Mihara, Haruka Fujinami, Tsutomu Fujii, Ichiro Yasuda
Summary: This study aimed to identify factors associated with the induction of third-line chemotherapy for advanced gastric cancer, focusing on patient eligibility for clinical trial. The results showed that factors such as ineligibility for clinical trials, number of metastatic sites, low albumin concentration, and a lack of response to first-line treatment were associated with the initiation of third-line chemotherapy. Additionally, the study suggested that patients who responded to first-line treatment had more favorable prognoses when treated with salvage chemotherapy, even if they did not meet the eligibility criteria for clinical trials.
Article
Gastroenterology & Hepatology
Hiroshi Mihara, Kunitoshi Uchida, Yoshiyuki Watanabe, Sohachi Nanjo, Miho Sakumura, Iori Motoo, Takayuki Ando, Masami Minemura, Jibran Sualeh Muhammad, Hiroyuki Yamamoto, Fumio Itoh, Ichiro Yasuda
Summary: This study investigated the regulatory mechanisms and expression of TRPV4 in colon epithelial cells co-cultured with various intestinal bacteria. The results showed that co-culture with certain bacteria temporarily decreased TRPV4 expression, while co-culture with other bacteria increased TRPV4 expression. Additionally, TRPV4 expression was higher in constipated patients and correlated with increased frequency of E. faecalis.
BMC GASTROENTEROLOGY
(2023)
Review
Gastroenterology & Hepatology
Akira Teramoto, Seiji Hamada, Banri Ogino, Ichiro Yasuda, Yasushi Sano
Summary: Narrow-band imaging (NBI) is an optical digital enhancement method that allows the observation of vascular and surface structures of colorectal lesions. Despite some issues in earlier models, NBI has evolved and the newest endoscopic platform offers significantly brighter and detailed images. Increased visualization and universal compatibility across all scopes are expected to improve the detection and diagnosis of polyps and promote global standardization. Knowledge of NBI and magnifying colonoscopy will become essential for future endoscopic practice.
DIGESTIVE ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Kosuke Takahashi, Ichiro Yasuda, Nobuhiko Hayashi, Takuji Iwashita, Mitsuru Okuno, Tsuyoshi Mukai, Masatoshi Mabuchi, Seiji Adachi, Shinpei Doi, Johji Imura, Eisuke Ozawa, Hisamitsu Miyaaki, Kazuhiko Nakao
Summary: Compared to 12 TAFs, EUS-FNB with 3 TAFs showed noninferior diagnostic sensitivity and accuracy for solid pancreatic lesions, with less blood contamination in the sampled tissues.
GASTROINTESTINAL ENDOSCOPY
(2023)
Review
Gastroenterology & Hepatology
Takuji Iwashita, Keisuke Iwata, Tsuyoshi Hamada, Tomotaka Saito, Hideyuki Shiomi, Mamoru Takenaka, Akinori Maruta, Shinya Uemura, Atsuhiro Masuda, Saburo Matsubara, Tsuyoshi Mukai, Sho Takahashi, Nobuhiko Hayashi, Hiroyuki Isayama, Ichiro Yasuda, Yousuke Nakai
Summary: Pancreatic fluid collections are complications of acute and chronic pancreatitis. Endoscopic drainage and necrosectomy are less invasive treatment options for these collections. However, the importance of non-interventional supportive care during the periprocedural period has not been fully discussed.
JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Gastroenterology & Hepatology
Raymond S. Y. Tang, Onuma Sattayalertyanyong, Yu-Ting Kuo, Kenneth H. Park, Constantinos Anastassiades, Dario Ligresti, Nobuhiko Hayashi, Aws Hasan, Tae-Hyeon Kim, Nonthalee Pausawasdi, Hsiu-Po Wang, Simon K. Lo, Khek-Yu Ho, Luca Barresi, Mario Traina, Ichiro Yasuda, Thomas J. Savides, Chieh-Sian Koo, Ting Ting Chan, Thomas Y. T. Lam, Joseph J. Y. Sung
Summary: This study aimed to evaluate the impact of COVID-19 on the outcomes of pancreatobiliary IgG4-related disease (IgG4-RD) patients. The results showed a low COVID-19 infection rate in IgG4-RD patients during the pre-vaccination period, and no exacerbation of IgG4-RD was observed following COVID-19 infection or vaccination.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Yuno Goto, Kazuto Tajiri, Shinichi Tanaka, Aiko Murayama, Nozomu Muraishi, Yuka Hayashi, Ichiro Yasuda
Summary: Sarcomatoid hepatocellular carcinoma (sHCC) is a rare and highly aggressive form of liver cancer that has no established pharmacological treatment. This study reports a case of sHCC that emerged two years after radiofrequency ablation (RFA), but was managed successfully with interventional therapies and immunotherapy. The findings suggest that combined immunotherapy may be effective in treating sHCC, but further research is needed to determine its efficacy in a larger patient population.
CLINICAL JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Gastroenterology & Hepatology
Kazuto Tajiri, Kazuhiko Okada, Hiroyuki Ito, Kengo Kawai, Yoshiro Kashii, Yoshiharu Tokimitsu, Nozomu Muraishi, Aiko Murayama, Yuka Hayashi, Masami Minemura, Terumi Takahara, Yukihiro Shimizu, Ichiro Yasuda
Summary: This multicenter study evaluated the long-term changes in thrombocytopenia and leukocytopenia in HCV-cirrhosis patients treated with DAAs. The results showed that DAA treatment improved thrombocytopenia and leukocytopenia and also led to a reduction in liver fibrosis markers and spleen size over a 5-year period.
BMC GASTROENTEROLOGY
(2023)
Article
Medicine, Research & Experimental
Tatsuya Sato, Tomotaka Saito, Mamoru Takenaka, Takuji Iwashita, Hideyuki Shiomi, Toshio Fujisawa, Nobuhiko Hayashi, Keisuke Iwata, Akinori Maruta, Tsuyoshi Mukai, Atsuhiro Masuda, Saburo Matsubara, Tsuyoshi Hamada, Tadahisa Inoue, Hiroshi Ohyama, Masaki Kuwatani, Hideki Kamada, Shinichi Hashimoto, Toshiyasu Shiratori, Reiko Yamada, Hirofumi Kogure, Takeshi Ogura, Kazunari Nakahara, Shinpei Doi, Kenji Chinen, Hiroyuki Isayama, Ichiro Yasuda, Yousuke Nakai
Summary: With the increasing popularity of endoscopic ultrasound (EUS)-guided transmural interventions, the management of walled-off necrosis (WON) of the pancreas is still debatable. This study aims to compare the efficacy and safety of immediate direct endoscopic necrosectomy (DEN) with the drainage-oriented step-up approach for WON patients. Evaluation: 8 out of 10.
Article
Gastroenterology & Hepatology
Shinpei Doi, Yuta Namura, Tomohiro Kikuyama, Go Saito, Takako Adachi, Kotaro Matsumoto, Ayako Watanabe, Hiromichi Tsunashima, Nobuhiro Katsukura, Takayuki Tsujikawa, Ichiro Yasuda
Summary: This study aimed to evaluate the safety and efficacy of a newly developed distal tapered covered metal stent (TMS) for distal malignant biliary obstruction (DMBO). The results showed that endoscopic placement of TMS in DMBO patients is technically feasible and safe, with a remarkably long time to recurrent biliary obstruction (TRBO).
ENDOSCOPY INTERNATIONAL OPEN
(2023)
Article
Gastroenterology & Hepatology
Tomotaka Saito, Shunsuke Omoto, Mamoru Takenaka, Masahiro Tsujimae, Atsuhiro Masuda, Tatsuya Sato, Tsuyoshi Hamada, Shogo Ota, Hideyuki Shiomi, Sho Takahashi, Toshio Fujisawa, Keito Nakagawa, Saburo Matsubara, Shinya Uemura, Takuji Iwashita, Kensaku Yoshida, Akinori Maruta, Mitsuru Okuno, Keisuke Iwata, Nobuhiko Hayashi, Tsuyoshi Mukai, Hiroyuki Isayama, Ichiro Yasuda, Yousuke Nakai, WONDERFUL study grp Japan
Summary: A study of 357 patients receiving EUS-guided treatment for pancreatic fluid collections (PFCs) found that adverse events were more likely to occur in patients with walled-off necrosis (WON) and risk factors included WON extension to the pelvis and endoscopic necrosectomy. Higher Charlson Comorbidity Index, extension to the pelvis, nonuse of a lumen-apposing metal stent, and percutaneous drainage were risk factors for clinical failure in WON treatment. Patients with pseudocysts extending to the paracolic gutter and those who needed more than two endoscopic/percutaneous procedures had a higher risk of clinical failure.
DIGESTIVE ENDOSCOPY
(2023)
Article
Oncology
Iori Motoo, Takayuki Ando, Takeru Hamashima, Shinya Kajiura, Miho Sakumura, Yuko Ueda, Aiko Murayama, Kohei Ogawa, Kenichiro Tsukada, Akira Ueda, Nobuhiro Suzuki, Naokatsu Nakada, Koji Nakashima, Ayumu Hosokawa, Ichiro Yasuda
Summary: This study aimed to analyze the progression pattern and mechanism of response to ICIs in patients with gastric cancer. Non-systemic progression was associated with improved overall survival, while liver metastasis was a predictive factor of systemic progression during ICIs.
FRONTIERS IN ONCOLOGY
(2023)
Letter
Gastroenterology & Hepatology
Tatsuya Sato, Ichiro Yasuda, Yousuke Nakai
