Review
Cell Biology
Christoph Seger, Sonja Sturm
Summary: NMR spectroscopy is essential for determining the structural information of analytes from natural sources in liquid state. While mass spectrometry can differentiate and group biomarkers, the structural characterization often requires the use of NMR spectroscopy.
Article
Agriculture, Multidisciplinary
Junbin Wei, Xin Zhang, Ruihao Zhong, Bin Liu, Xuelian Zhang, Fang Fang, Zhaoqi Zhang, Xuequn Pang
Summary: After harvest, litchi pericarp quickly turns brown, with decreases in (-)-epicatechin and procyanidins contents. The enzyme ADE/LAC plays a critical role in catalyzing the conversion of procyanidins, contributing to the browning process of the pericarp.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Chemistry, Analytical
He-Ying Liu, Qi-Zhen Cheng, Hui-Zheng Fu, Zhen-Hua Zhong, Hong-Ying Xia, Yan-Fang Guo, Shuang-Shuang Zheng, Shi-Shi Yu
Summary: In this study, five impurities in cloperastine hydrochloride bulk drug were isolated and identified, and a quantitative HPLC method was developed for detection. The structures of these impurities were characterized using various spectral data, with some identified as new isomers or intermediates of cloperastine.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2021)
Article
Food Science & Technology
Jose Thiago do Carmo Santos, Fabiane Cristina Petry, Eric de Castro Tobaruela, Adriana Zerlotti Mercadante, Maria Beatriz Abreu Gloria, Ana Maria Costa, Franco Maria Lajolo, Neuza Mariko Aymoto Hassimotto
Summary: Passiflora tenuifila, a Brazilian native passion fruit, is a dietary source of bioactive compounds with potential biological activity. The study found that the fruit is a good source of dietary fiber and maintains its bioactive compound contents and nutritional value at both mature-green and ripe stages. Carotenoids were responsible for the separation of the two ripening stages.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Horticulture
Lina M. Londono-Giraldo, Monica Bueno, Eduardo Corpas-Iguaran, Gonzalo Taborda-Ocampo, Alejandro Cifuentes
Summary: Carotenoids are naturally occurring antioxidants found in many organisms, with different cherry tomato varieties having varying carotenoid profiles and quantities. Wild red tomatoes have higher lycopene content than commercial tomatoes, while yellow tomatoes lack lycopene. Varieties with higher concentrations of carotenoids may have antioxidant activity. This study utilized HPLC-DAD-APCI-MS to analyze wild cherry tomato accessions, showing promising functional traits for potential commercial applications and local social projects.
Review
Environmental Sciences
Aikaterini A. Zompra, Styliani A. Chasapi, Matthew S. Twigg, Karina Salek, Ioannis Anestopoulos, Alex Galanis, Aglaia Pappa, Tony Gutierrez, Ibrahim M. Banat, Roger Marchant, Stephen R. Euston, Mihalis I. Panayiotidis, Georgios A. Spyroulias
Summary: Synthetic surfactants, commonly used in various industries, have a negative impact on the environment due to their synthetic preparation. As a result, there is a growing interest in exploring natural sources of surfactants, which can be produced through environmentally friendly processes. Microbial production of such chemicals, however, often results in crude materials composed of multiple complex bioproducts. Therefore, advanced analytical methods are required for the extraction, identification, and characterization of biosurfactants.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Food Science & Technology
Hassan Zia, Nadine Fischbach, Mikko Hofsommer, Ana Slatnar
Summary: A multivitamin analysis method was developed for the determination of nine major B vitamins in fruit juices using HPLC coupled with mass spectrometry. The method involved chromatographic separation on a reverse phase column using a gradient elution mode. Sample preparation was simple and method validation was conducted to ensure accuracy. The study concludes that this method has the potential to be used in quality control laboratories for routine vitamin analysis.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Iris Batista Leite, Carolina Duque Magalhaes, Mariana Monteiro, Eliane Fialho
Summary: The addition of honey improves the nutritional and sensorial characteristics of an apple and passion fruit mixed beverage, enhancing its taste and antioxidant properties. Honey also increases the total soluble solids content and antioxidant values of the beverage.
Article
Plant Sciences
Mohd Amir, Ameeduzzafar Zafar, Rizwan Ahmad, Wasim Ahmad, Mohammad Sarafroz, Mohammad Khalid, Mohammed M. Ghoneim, Sultan Alshehri, Shadma Wahab, Sayeed Ahmad, Mohd Mujeeb
Summary: The increase in the use of herbal medicines has led to more stringent regulations for quality variation and standardization. This study aimed to standardize Prunus domestica Linn. using various evaluation techniques, advanced instrumental analysis, and biological and toxicological techniques. The results showed that the fruit met quality requirements and did not contain harmful substances beyond the permissible limits.
Article
Chemistry, Applied
Aghiles Karim Aissat, Nassima Chaher-Bazizi, Tristan Richard, Dina Kilani-Atmani, Eric Pedrot, Elodie Renouf, Djebbar Atmani, Josep Valls Fonayet
Summary: This study investigated the phenolic composition of Pistacia lentiscus L. fruits at different physiological stages. The results revealed significant variation in the qualitative and quantitative content of phenolic compounds during fruit ripening, suggesting potential applications as nutraceuticals and food colorants.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Review
Biochemistry & Molecular Biology
Vassiliki G. Kontogianni, Ioannis P. Gerothanassis
Summary: This review critically analyzes various methods for lipid hydroperoxide analysis and emphasizes analytical and structural methods that significantly contribute to the molecular basis of lipid hydroperoxide formation without the need for isolation of individual components.
Article
Chemistry, Multidisciplinary
Jyoti Kannoujia, Devendra Nagineni, Ramesh Rodda, Ramesh Chilukuri, Jagadeesh Babu Nanubolu, Parameswari Akshinthala, Soujanya Yarasi, Srinivas Kantevari, Prabhakar Sripadi
Summary: Identification and characterization of impurities in agrochemicals are crucial for their efficacy and public health safety. In this study, we identified and characterized an impurity, 5-chloro-2-cyano-N,N-dimethyl-4-p-tolylimidazole-1-sulfonamide (2), in the fungicide cyazofamid. HPLC analysis suggested that 2 is formed during the reaction of substituted imidazole (1) with N,N-dimethylsulfamoyl chloride. Preparative HPLC isolation and characterization by various techniques confirmed that 2 is an isomer of cyazofamid with the N,N-dimethyl sulfonamide group positioned on the other nitrogen of imidazole near the chloride group. Computational studies further supported the formation of 2 and ruled out other possible isomeric structures.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Food Science & Technology
Martina Gagliano, Carmela Conidi, Lucia Bartella, Rosachiara A. Salvino, Leonardo Di Donna, Alfredo Cassano, Giuseppina De Luca
Summary: This study focused on analyzing Calabrian apple juices from four different cultivars to characterize metabolites and explore the use of membrane operations for extracting antioxidants. By combining NMR and HPLC-UV-ESI-MS/MS, the metabolic profiles of different juice varieties were identified, with Golden Delicious selected for membrane filtration tests due to its high phenolic content. Membrane filtration was found to be effective in concentrating antioxidants from the juice extracts.
FOOD AND BIOPROCESS TECHNOLOGY
(2021)
Article
Agriculture, Multidisciplinary
Siwei Wang, Xiaonan Wang, Hong Chang, Haibin Sun, Yanping Liu
Summary: An efficient and sensitive method was developed to detect pesticides and their metabolites in fruits and vegetables. The method showed good precision and reproducibility, and was used to evaluate the dietary risk to Chinese consumers. This study provides a reliable analytical method for monitoring purposes and important guidance for food safety and export.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Plant Sciences
Fatma Tosun, Fatih Goger, Gokalp Iscan, Mine Kurkcuoglu, Fadil Kaan Kuran, Mahmut Miski
Summary: In this study, the fruit essential oil and antioxidant-rich methanolic extracts of Ferula drudeana were analyzed to determine its medicinal properties and unique characteristics compared to other Ferula species. The main components of the fruit essential oil were shyobunone (44.2%) and 6-epishyobunone (12.6%). The extracts showed varying levels of antibacterial and anticandidal activity, with the root's petroleum ether extract exhibiting remarkable inhibitory activity against Candida krusei and Candida utilis. Additionally, both fruit and root extracts demonstrated strong antioxidant activity.
Article
Nutrition & Dietetics
Elizabeth M. Grainger, Nancy E. Moran, David M. Francis, Steven J. Schwartz, Lei Wan, Jennifer Thomas-Ahner, Rachel E. Kopec, Ken M. Riedl, Gregory S. Young, Ronney Abaza, Robert R. Bahnson, Steven K. Clinton
JOURNAL OF NUTRITION
(2019)
Article
Nutrition & Dietetics
Nancy E. Moran, Jennifer M. Thomas-Ahner, Jessica L. Fleming, Joseph P. McElroy, Rebecca Mehl, Elizabeth M. Grainger, Ken M. Riedl, Amanda E. Toland, Steven J. Schwartz, Steven K. Clinton
JOURNAL OF NUTRITION
(2019)
Article
Food Science & Technology
Junnan Gu, Jennifer M. Thomas-Ahner, Kenneth M. Riedl, Michael T. Bailey, Yael Vodovotz, Steven J. Schwartz, Steven K. Clinton
MOLECULAR NUTRITION & FOOD RESEARCH
(2019)
Article
Chemistry, Analytical
Michael P. Dzakovich, Elisabet Gas-Pascual, Caleb J. Orchard, Eka N. Sari, Ken M. Riedl, Steven J. Schwartz, David M. Francis, Jessica L. Cooperstone
JOURNAL OF AOAC INTERNATIONAL
(2019)
Article
Immunology
Emily R. Bowman, Manjusha Kulkarni, Janelle Gabriel, Morgan J. Cichon, Kenneth Riedl, Martha A. Belury, Jordan E. Lake, Brian Richardson, Cheryl Cameron, Mark Cameron, Susan L. Koletar, Michael M. Lederman, Scott F. Sieg, Nicholas T. Funderburg
FRONTIERS IN IMMUNOLOGY
(2019)
Article
Food Science & Technology
Geoffrey Y. Sasaki, Jinhui Li, Morgan J. Cichon, Ken M. Riedl, Rachel E. Kopec, Richard S. Bruno
MOLECULAR NUTRITION & FOOD RESEARCH
(2019)
Article
Food Science & Technology
Kristen M. Roberts, Elizabeth M. Grainger, Jennifer M. Thomas-Ahner, Alice Hinton, Junnan Gu, Ken Riedl, Yael Vodovotz, Ronney Abaza, Steven J. Schwartz, Steven K. Clinton
MOLECULAR NUTRITION & FOOD RESEARCH
(2020)
Article
Microbiology
Emily R. Bowman, Cheryl M. Cameron, Brian Richardson, Manjusha Kulkarni, Janelle Gabriel, Morgan J. Cichon, Kenneth M. Riedl, Yousef Mustafa, Michael Cartwright, Brandon Snyder, Subha V. Raman, David A. Zidar, Susan L. Koletar, Martin P. Playford, Nehal N. Mehta, Scott F. Sieg, Michael L. Freeman, Michael M. Lederman, Mark J. Cameron, Nicholas T. Funderburg
Article
Hematology
Tzu-Fei Wang, Amanda P. Waller, Ella Lin, Lai Wei, Abigail Bartosic, Ken Riedl, Bryce A. Kerlin
Summary: This pilot study aimed to investigate the effects of statins in addition to anticoagulation in patients with acute VTE, but found that statins did not significantly reduce thrombin generation. Although atorvastatin significantly reduced LDL levels at 3 months, it had no impact on d-dimer or high-sensitivity-C reactive protein. The study was terminated early due to low recruitment rate and barriers to enrollment.
BLOOD COAGULATION & FIBRINOLYSIS
(2021)
Article
Immunology
Sahera Dirajlal-Fargo, Abdus Sattar, Jiao Yu, Zainab Albar, Fabio C. Chaves, Ken Riedl, Cissy Kityo, Emily Bowman, Grace A. McComsey, Nicholas Funderburg
Summary: The study shows that the serum lipidome is altered in young virally suppressed PHIV on ART, with biomarkers associated with CVD risk and T-cell activation being positively correlated with lipid species in PHIV.
Letter
Nutrition & Dietetics
Emily B. Hill, Ashley J. Kennedy, Kristen M. Roberts, Ken M. Riedl, Elizabeth M. Grainger, Steven K. Clinton
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS
(2021)
Article
Oncology
Divya Nedungadi, Nathan Ryan, Kelvin Anderson, Felipe F. Lamenza, Pete P. Jordanides, Michael J. Swingler, Liva Rakotondraibe, Kenneth M. Riedl, Hans Iwenofu, Steve Oghumu
Summary: Recent reports have highlighted the significance of glucocorticoids synthesized in the oral mucosa in cancer development. This study investigates the role of the oral glucocorticoid system in oral cancer, and explores the effect of black raspberry administration on glucocorticoid modulation during oral cancer chemoprevention. The findings demonstrate the downregulation of HSD11B2, an enzyme that inactivates cortisol, during oral carcinogenesis, and show that black raspberry administration can upregulate HSD11B2 expression and reduce active glucocorticoid levels in oral cancer cells.
Meeting Abstract
Oncology
M. Bittoni, A. Bibi, N. Williams, M. Mendelson, E. Grainger, Y. Vodovitz, K. Riedl, S. Clinton, D. Carbone, D. Spakowicz
JOURNAL OF THORACIC ONCOLOGY
(2021)
Correction
Multidisciplinary Sciences
G. Astrid Garzon, Carlos Y. Soto, Marcela Lopez-R, Kenneth M. Riedl, Cindi R. Browmiller, Luke Howard
Article
Multidisciplinary Sciences
G. Astrid Garzon, Carlos Y. Soto, Marcela Lopez-R, Kenneth M. Riedl, Cindi R. Browmiller, Luke Howard