Journal
JOURNAL OF FOOD SCIENCE
Volume 74, Issue 6, Pages R73-R78Publisher
WILEY
DOI: 10.1111/j.1750-3841.2009.01245.x
Keywords
bacterial spores; microbial survival; modeling
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Over the course of 2 days, top researchers in the fields of bacterial spore biology and computational biology discussed approaches to determine the cause of spore germination heterogeneity. Biological and mathematical data gaps were identified, and experimental approaches and computational strategies for modeling spore germination were presented and evaluated. As a result of these interactions, future research directions were defined, the outcome of which should result in a robust model to help define the molecular mechanism(s) of spore germination. Mechanistic understanding of germination will be instrumental for developing novel sterilization, treatment, and decontamination strategies to mitigate threats posed by spores.
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