Molecular mechanisms of paralogous compensation and the robustness of cellular networks

Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes

(2013) Jacqueline K. White et al.   CELL

Gene Copy-Number Alterations: A Cost-Benefit Analysis

(2013) Yun-Chi Tang et al.   CELL

A novel single-cell screening platform reveals proteome plasticity during yeast stress responses

(2013) Michal Breker et al.   JOURNAL OF CELL BIOLOGY

Following Gene Duplication, Paralog Interference Constrains Transcriptional Circuit Evolution

(2013) Christopher R. Baker et al.   SCIENCE

A Systematic Approach for the Genetic Dissection of Protein Complexes in Living Cells

(2013) Guillaume Diss et al.   Cell Reports

The Ribosomal Protein Rpl22 Controls Ribosome Composition by Directly Repressing Expression of Its Own Paralog, Rpl22l1

(2013) Monique N. O'Leary et al.   PLoS Genetics

Biological Robustness: Paradigms, Mechanisms, and Systems Principles

(2012) James Michael Whitacre   Frontiers in Genetics

Cryptic genetic variation promotes rapid evolutionary adaptation in an RNA enzyme

(2011) Eric J. Hayden et al.   NATURE

Predicting mutation outcome from early stochastic variation in genetic interaction partners

(2011) Alejandro Burga et al.   NATURE

Origins, evolution, and phenotypic impact of new genes

(2010) H. Kaessmann   GENOME RESEARCH

Functional Compensation of Primary and Secondary Metabolites by Duplicate Genes in Arabidopsis thaliana

(2010) K. Hanada et al.   MOLECULAR BIOLOGY AND EVOLUTION

A general lack of compensation for gene dosage in yeast

(2010) Michael Springer et al.   Molecular Systems Biology

Genes Confer Similar Robustness to Environmental, Stochastic, and Genetic Perturbations in Yeast

(2010) Ben Lehner   PLoS One

Robustness and Evolvability

(2010) Joanna Masel et al.   TRENDS IN GENETICS

Maintenance of duplicate genes and their functional redundancy by reduced expression

(2010) Wenfeng Qian et al.   TRENDS IN GENETICS

Need-Based Up-Regulation of Protein Levels in Response to Deletion of Their Duplicate Genes

(2010) Alexander DeLuna et al.   PLOS BIOLOGY

The Cellular Robustness by Genetic Redundancy in Budding Yeast

(2010) Jingjing Li et al.   PLoS Genetics

Genetic Redundancy: New Tricks for Old Genes

(2009) Ran Kafri et al.   CELL

Evolutionary Persistence of Functional Compensation by Duplicate Genes in Arabidopsis

(2009) Kousuke Hanada et al.   Genome Biology and Evolution

'Edgetic' perturbation of a C. elegans BCL2 ortholog

(2009) Matija Dreze et al.   NATURE METHODS

Robustness: mechanisms and consequences

(2009) Joanna Masel et al.   TRENDS IN GENETICS

The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast

(2008) G. Musso et al.   GENOME RESEARCH

Distributed robustness in cellular networks: insights from synthetic evolved circuits

(2008) J. Macia et al.   Journal of the Royal Society Interface

Exposing the fitness contribution of duplicated genes

(2008) Alexander DeLuna et al.   NATURE GENETICS

Turning a hobby into a job: How duplicated genes find new functions

(2008) Gavin C. Conant et al.   NATURE REVIEWS GENETICS

A genome-wide view of the spectrum of spontaneous mutations in yeast

(2008) M. Lynch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preferential protection of protein interaction network hubs in yeast: Evolved functionality of genetic redundancy

(2008) R. Kafri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems biology spins off a new model for the study of canalization

(2008) Christian R. Landry   TRENDS IN ECOLOGY & EVOLUTION

Evolution of a New Function by Degenerative Mutation in Cephalochordate Steroid Receptors

(2008) Jamie T. Bridgham et al.   PLoS Genetics

Pervasive and Persistent Redundancy among Duplicated Genes in Yeast

(2008) E. Jedediah Dean et al.   PLoS Genetics

Role of Duplicate Genes in Robustness against Deleterious Human Mutations

(2008) Tzu-Lin Hsiao et al.   PLoS Genetics