Pathogenic CD4+T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes

Autoimmunity to Both Proinsulin and IGRP Is Required for Diabetes in Nonobese Diabetic 8.3 TCR Transgenic Mice

(2014) B. Krishnamurthy et al.   JOURNAL OF IMMUNOLOGY

Defining the Transcriptional and Cellular Landscape of Type 1 Diabetes in the NOD Mouse

(2013) Javier A. Carrero et al.   PLoS One

Following the Fate of One Insulin-Reactive CD4 T cell

(2012) Georgia Fousteri et al.   DIABETES

Thymic negative selection is functional in NOD mice

(2012) Michael Mingueneau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen presentation events in autoimmune diabetes

(2011) Boris Calderon et al.   CURRENT OPINION IN IMMUNOLOGY

Register shifting of an insulin peptide–MHC complex allows diabetogenic T cells to escape thymic deletion

(2011) James F. Mohan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response

(2011) B. Calderon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans

(2011) B. Calderon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse

(2011) F. Crawford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes

(2010) James F Mohan et al.   NATURE IMMUNOLOGY

A protocol for islet isolation from mouse pancreas

(2009) Dong-Sheng Li et al.   Nature Protocols

Insulin as an autoantigen in NOD/human diabetes

(2008) Li Zhang et al.   CURRENT OPINION IN IMMUNOLOGY

Conserved T cell receptor  -chain induces insulin autoantibodies

(2008) M. Kobayashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cells in islets of Langerhans constitutively present   cell-derived peptides bound to their class II MHC molecules

(2008) B. Calderon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA