Conversion ofHelicobacter pyloriCagA from senescence inducer to oncogenic driver through polarity-dependent regulation of p21

Helicobacter pylori Exploits Host Membrane Phosphatidylserine for Delivery, Localization, and Pathophysiological Action of the CagA Oncoprotein

(2010) Naoko Murata-Kamiya et al.   Cell Host & Microbe

Inhibition of Rho-Associated Kinase Signaling Prevents Breast Cancer Metastasis to Human Bone

(2009) S. Liu et al.   CANCER RESEARCH

Twist1-Mediated Adriamycin-Induced Epithelial-Mesenchymal Transition Relates to Multidrug Resistance and Invasive Potential in Breast Cancer Cells

(2009) Q.-Q. Li et al.   CLINICAL CANCER RESEARCH

Differential oncogenic potential of geographically distinctHelicobacter pyloriCagA isoforms in mice

(2009) Motohiro Miura et al.   INTERNATIONAL JOURNAL OF CANCER

Phosphorylated Extracellular Signal-regulated Protein Kinases 1 and 2 Phosphorylate Sp1 on Serine 59 and Regulate Cellular Senescence via Transcription of p21Sdi1/Cip1/Waf1

(2009) Hong Seok Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Partitioning-defective 1/Microtubule Affinity-regulating Kinases in the Morphogenetic Activity ofHelicobacter pyloriCagA

(2009) Huaisheng Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells

(2009) M. Kajita et al.   JOURNAL OF CELL SCIENCE

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease

(2009) Hervé Acloque et al.   JOURNAL OF CLINICAL INVESTIGATION

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

CagA Associates with c‐Met, E‐Cadherin, and p120‐Catenin in a Multiproteic Complex That SuppressesHelicobacter pylori–Induced Cell‐Invasive Phenotype

(2009) Maria Jose Oliveira et al.   JOURNAL OF INFECTIOUS DISEASES

Sp1 Phosphorylation and Its Regulation of Gene Transcription

(2009) N. Y. Tan et al.   MOLECULAR AND CELLULAR BIOLOGY

Characterization of the interface between normal and transformed epithelial cells

(2009) Catherine Hogan et al.   NATURE CELL BIOLOGY

Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates

(2009) Dragana Nes̆ić et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

p21CIP1attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo

(2009) Manran Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA

(2008) Shuh-hei Fujishiro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes

(2008) M. Inomata et al.   BLOOD

Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence

(2008) Stéphane Ansieau et al.   CANCER CELL

Emerging Role of miR-106b-25/miR-17-92 Clusters in the Control of Transforming Growth Factor   Signaling

(2008) F. Petrocca et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Analysis of detergent-resistant membranes of Helicobacter pylori infected gastric adenocarcinoma cells reveals a role for MARK2/Par1b in CagA-mediated disruption of cellular polarity

(2008) Zaher Zeaiter et al.   CELLULAR MICROBIOLOGY

Importance of EGF receptor, HER2/Neu and Erk1/2 kinase signalling for host cell elongation and scattering induced by theHelicobacter pyloriCagA protein: antagonistic effects of the vacuolating cytotoxin VacA

(2008) Nicole Tegtmeyer et al.   CELLULAR MICROBIOLOGY

SagA of CagA in Helicobacter pylori pathogenesis

(2008) Masanori Hatakeyama   CURRENT OPINION IN MICROBIOLOGY

Zeb1 links epithelial-mesenchymal transition and cellular senescence

(2008) Y. Liu et al.   DEVELOPMENT

Functional association between the Helicobacter pylori virulence factors VacA and CagA

(2008) R. H. Argent et al.   JOURNAL OF MEDICAL MICROBIOLOGY

GEF-H1 Couples Nocodazole-induced Microtubule Disassembly to Cell Contractility via RhoA

(2008) Yuan-Chen Chang et al.   MOLECULAR BIOLOGY OF THE CELL

Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse

(2008) N. Ohnishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis?

(2008) Jörg Birkenfeld et al.   TRENDS IN CELL BIOLOGY