Myeloid cells, BAFF, and IFN-γ establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice

Excessive Production of IFN-  in Patients with Systemic Lupus Erythematosus and Its Contribution to Induction of B Lymphocyte Stimulator/B Cell-Activating Factor/TNF Ligand Superfamily-13B

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Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus–prone B6.Sle1.Yaaanimals

(2009) Kenichiro Maeda et al.   BLOOD

BAFF: a local and systemic target in autoimmune diseases

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Multiple roles of Lyn kinase in myeloid cell signaling and function

(2009) Patrizia Scapini et al.   IMMUNOLOGICAL REVIEWS

Autoimmune Disease in Lyn-Deficient Mice Is Dependent on an Inflammatory Environment Established by IL-6

(2009) E. Tsantikos et al.   JOURNAL OF IMMUNOLOGY

Developmental Acquisition of the Lyn-CD22-SHP-1 Inhibitory Pathway Promotes B Cell Tolerance

(2009) A. J. Gross et al.   JOURNAL OF IMMUNOLOGY

Interleukin 6 (IL-6) Deficiency Delays Lupus Nephritis in MRL-Faslpr Mice: The IL-6 Pathway as a New Therapeutic Target in Treatment of Autoimmune Kidney Disease in Systemic Lupus Erythematosus

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B-cell-directed therapies for autoimmune disease

(2009) Thomas Dörner et al.   Nature Reviews Rheumatology

BAFF and the plasticity of peripheral B cell tolerance

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Belimumab, an anti-BLyS human monoclonal antibody for potential treatment of inflammatory autoimmune diseases

(2008) Changhai Ding   EXPERT OPINION ON BIOLOGICAL THERAPY

BAFF blockade for systemic lupus erythematosus: will the promise be fulfilled?

(2008) Meera Ramanujam et al.   IMMUNOLOGICAL REVIEWS

B-lymphocyte contributions to human autoimmune disease

(2008) Koichi Yanaba et al.   IMMUNOLOGICAL REVIEWS

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis

(2008) Q. Lai Kwan Lam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact

(2008) J. L. Scholz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of B-cell-activating factor (BAFF)/B lymphocyte stimulator (BLyS) expression in human neutrophils

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