Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity

Getting TRAIL back on track for cancer therapy

(2014) J Lemke et al.   CELL DEATH AND DIFFERENTIATION

A role for TRAIL/TRAIL-R2 in radiation-induced apoptosis and radiation-induced bystander response of human neural stem cells

(2013) Vladimir N. Ivanov et al.   APOPTOSIS

Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells

(2013) Sean P. Cullen et al.   MOLECULAR CELL

Dual Inactivation of Akt and ERK by TIC10 Signals Foxo3a Nuclear Translocation, TRAIL Gene Induction, and Potent Antitumor Effects

(2013) J. E. Allen et al.   Science Translational Medicine

Paracrine control of tissue regeneration and cell proliferation by Caspase-3

(2013) K Boland et al.   Cell Death & Disease

Apoptotic cells can induce non-autonomous apoptosis through the TNF pathway

(2013) Ainhoa Pérez-Garijo et al.   eLife

Proapoptotic Activation of Death Receptor 5 on Tumor Endothelial Cells Disrupts the Vasculature and Reduces Tumor Growth

(2012) Nicholas S. Wilson et al.   CANCER CELL

Kinetics in Signal Transduction Pathways Involving Promiscuous Oligomerizing Receptors Can Be Determined by Receptor Specificity: Apoptosis Induction by TRAIL

(2012) Eva Szegezdi et al.   MOLECULAR & CELLULAR PROTEOMICS

A Heterogeneous In Vitro Three Dimensional Model of Tumour-Stroma Interactions Regulating Sprouting Angiogenesis

(2012) Pedro Correa de Sampaio et al.   PLoS One

High TRAIL-R3 expression on leukemic blasts is associated with poor outcome and induces apoptosis-resistance which can be overcome by targeting TRAIL-R2

(2011) M.E.D. Chamuleau et al.   LEUKEMIA RESEARCH

Regulating TRAIL Receptor-Induced Cell Death at the Membrane: A Deadly Discussion

(2011) Sarah Shirley et al.   Recent Patents on Anti-Cancer Drug Discovery

Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants

(2011) C R Reis et al.   Cell Death & Disease

Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells

(2010) D Mahalingam et al.   BRITISH JOURNAL OF CANCER

Recurrence-free survival in prostate cancer is related to increased stromal TRAIL expression

(2010) Mariam Anees et al.   CANCER

Targeting AML through DR4 with a novel variant of rhTRAIL

(2010) Eva Szegezdi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Death receptor pathways mediate targeted and non-targeted effects of ionizing radiations in breast cancer cells

(2009) Audrey Luce et al.   CARCINOGENESIS

Prognostic significance of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor expression in patients with breast cancer

(2009) Tom M. Ganten et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

BioNumbers—the database of key numbers in molecular and cell biology

(2009) Ron Milo et al.   NUCLEIC ACIDS RESEARCH

TRAIL receptor signalling and modulation: Are we on the right TRAIL?

(2008) Devalingam Mahalingam et al.   CANCER TREATMENT REVIEWS

DR4-selective Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Variants Obtained by Structure-based Design

(2008) Vicente Tur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis

(2008) Niklas Finnberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor necrosis factor-related apoptosis inducing ligand-R4 decoy receptor expression is correlated with high Gleason scores, prostate-specific antigen recurrence, and decreased survival in patients with prostate carcinoma

(2007) Ismail T. Koksal et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS