Repression of Hox genes by LMP1 in nasopharyngeal carcinoma and modulation of glycolytic pathway genes by HoxC8

HOXC8 promotes breast tumorigenesis by transcriptionally facilitating cadherin-11 expression

(2015) Yong Li et al.   Oncotarget

Human Viral Oncogenesis: A Cancer Hallmarks Analysis

(2014) Enrique A. Mesri et al.   Cell Host & Microbe

The survival predictive significance of HOXC6 and HOXC8 in esophageal squamous cell carcinoma

(2014) Ya-Bing Du et al.   JOURNAL OF SURGICAL RESEARCH

Targeting Epstein–Barr virus oncoprotein LMP1-mediated glycolysis sensitizes nasopharyngeal carcinoma to radiation therapy

(2014) L Xiao et al.   ONCOGENE

Epigenetics in radiotherapy: Where are we heading?

(2014) Kim M. Smits et al.   RADIOTHERAPY AND ONCOLOGY

MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling

(2013) Su Jung Song et al.   CELL

Connecting Chromatin Modifying Factors to DNA Damage Response

(2013) Weiwei Lai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Reversing the Warburg Effect as a Treatment for Glioblastoma

(2013) Ethan Poteet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic targets for cancer therapy

(2013) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

TETonic shift: biological roles of TET proteins in DNA demethylation and transcription

(2013) William A. Pastor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epigenetics in radiation biology: a new research frontier

(2013) Matt Merrifield et al.   Frontiers in Genetics

Interplay between chromatin modifications and paused RNA polymerase II in dynamic transition between stalled and activated genes

(2012) Shuang Liu et al.   BIOLOGICAL REVIEWS

HoxB3 promotes prostate cancer cell progression by transactivating CDCA3

(2012) Jing Chen et al.   CANCER LETTERS

Epstein-Barr virus-encoded LMP1 triggers regulation of the ERK-mediated Op18/stathmin signaling pathway in association with cell cycle

(2012) Xuechi Lin et al.   CANCER SCIENCE

Nuclear epidermal growth factor receptor interacts with transcriptional intermediary factor 2 to activate cyclin D1 gene expression triggered by the oncoprotein latent membrane protein 1

(2012) Yin Shi et al.   CARCINOGENESIS

Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma

(2012) Christine Guo Lian et al.   CELL

Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us?

(2012) Ralph J. DeBerardinis et al.   CELL

Inhibition of  -KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

(2012) M. Xiao et al.   GENES & DEVELOPMENT

Epigenetic disruption of cadherin-11 in human cancer metastasis

(2012) F. Javier Carmona et al.   JOURNAL OF PATHOLOGY

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

(2012) H Yang et al.   ONCOGENE

Alterations of metabolic genes and metabolites in cancer

(2012) Eric K. Oermann et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Expression of HOXC8 is inversely related to the progression and metastasis of pancreatic ductal adenocarcinoma

(2011) H Adwan et al.   BRITISH JOURNAL OF CANCER

Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair

(2011) Salvatore Cortellino et al.   CELL

Paused RNA Polymerase II as a Developmental Checkpoint

(2011) Michael Levine   CELL

Microbiome and Malignancy

(2011) Claudia S. Plottel et al.   Cell Host & Microbe

LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation

(2011) Frederik J Verweij et al.   EMBO JOURNAL

Evidence for Alteration of EZH2, BMI1, and KDM6A and Epigenetic Reprogramming in Human Papillomavirus Type 16 E6/E7-Expressing Keratinocytes

(2011) P. L. Hyland et al.   JOURNAL OF VIROLOGY

The dynamic interplay in chromatin remodeling factors polycomb and trithorax proteins in response to DNA damage

(2011) Shuang Liu et al.   MOLECULAR BIOLOGY REPORTS

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

(2011) Daniel Cortázar et al.   NATURE

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

(2011) Kristine Williams et al.   NATURE

Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS

(2011) Yongguang Tao et al.   NUCLEIC ACIDS RESEARCH

The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas

(2011) L Li et al.   ONCOGENE

Id1 Interacts and Stabilizes the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) in Nasopharyngeal Epithelial Cells

(2011) Pok Man Hau et al.   PLoS One

Down-Regulation of EBV-LMP1 Radio-Sensitizes Nasal Pharyngeal Carcinoma Cells via NF-κB Regulated ATM Expression

(2011) Xiaoqian Ma et al.   PLoS One

Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming

(2011) Margaret E. McLaughlin-Drubin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Polymerase II Stalling Promotes Nucleosome Occlusion and pTEFb Recruitment to Drive Immortalization by Epstein-Barr Virus

(2011) Richard D. Palermo et al.   PLoS Pathogens

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency

(2010) Christian Popp et al.   NATURE

Lsh Mediated RNA Polymerase II Stalling at HoxC6 and HoxC8 Involves DNA Methylation

(2010) Yongguang Tao et al.   PLoS One

Conservation and divergence of methylation patterning in plants and animals

(2010) S. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway

(2010) P. Hajkova et al.   SCIENCE

Genome-Wide Evolutionary Analysis of Eukaryotic DNA Methylation

(2010) A. Zemach et al.   SCIENCE

Epigenetic Repression of p16INK4A by Latent Epstein-Barr Virus Requires the Interaction of EBNA3A and EBNA3C with CtBP

(2010) Lenka Skalska et al.   PLoS Pathogens

Regulation of Hox Gene Activity by Transcriptional Elongation in Drosophila

(2009) Vivek S. Chopra et al.   CURRENT BIOLOGY

Stalled Hox promoters as chromosomal boundaries

(2009) V. S. Chopra et al.   GENES & DEVELOPMENT

The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands

(2009) H. Takeshima et al.   GENOME RESEARCH

The emerging role of nuclear architecture in DNA repair and genome maintenance

(2009) Tom Misteli et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Epigenetic dysregulation of the host cell genome in Epstein–Barr virus-associated neoplasia

(2009) Hans Helmut Niller et al.   SEMINARS IN CANCER BIOLOGY

Lineage-Specific Polycomb Targets and De Novo DNA Methylation Define Restriction and Potential of Neuronal Progenitors

(2008) Fabio Mohn et al.   MOLECULAR CELL

Evidence for Hox and E2A–PBX1 collaboration in mouse T-cell leukemia

(2008) J Bijl et al.   ONCOGENE

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE

Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters

(2008) Leighton J. Core et al.   SCIENCE