PROX1 promotes hepatocellular carcinoma proliferation and sorafenib resistance by enhancing β-catenin expression and nuclear translocation
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Title
PROX1 promotes hepatocellular carcinoma proliferation and sorafenib resistance by enhancing β-catenin expression and nuclear translocation
Authors
Keywords
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Journal
ONCOGENE
Volume 34, Issue 44, Pages 5524-5535
Publisher
Springer Nature
Online
2015-02-16
DOI
10.1038/onc.2015.7
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Related references
Note: Only part of the references are listed.- PROX1 promotes hepatocellular carcinoma metastasis by way of up-regulating hypoxia-inducible factor 1α expression and protein stability
- (2013) Yanfeng Liu et al. HEPATOLOGY
- Prox1 Directly Interacts with LSD1 and Recruits the LSD1/NuRD Complex to Epigenetically Co-Repress CYP7A1 Transcription
- (2013) Huafang Ouyang et al. PLoS One
- Transcription factor PROX1: its role in development and cancer
- (2012) Tamador Elsir et al. CANCER AND METASTASIS REVIEWS
- Wnt-Pathway Activation in Two Molecular Classes of Hepatocellular Carcinoma and Experimental Modulation by Sorafenib
- (2012) A. Lachenmayer et al. CLINICAL CANCER RESEARCH
- Zinc finger transcription factor 191, directly binding to β-catenin promoter, promotes cell proliferation of hepatocellular carcinoma
- (2011) Guoyuan Liu et al. HEPATOLOGY
- Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis
- (2011) O. Karalay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inactivation of PI3K/AKT signaling inhibits glioma cell growth through modulation of β-catenin-mediated transcription
- (2010) Lei Han et al. BRAIN RESEARCH
- Tumor Suppressor Action of Liganded Thyroid Hormone Receptor β by Direct Repression of β-Catenin Gene Expression
- (2010) Celine J. Guigon et al. ENDOCRINOLOGY
- Sorafenib: a clinical and pharmacologic review
- (2010) Renuka Iyer et al. EXPERT OPINION ON PHARMACOTHERAPY
- Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
- (2010) Jacques Ferlay et al. INTERNATIONAL JOURNAL OF CANCER
- Prox1 Regulates the Notch1-Mediated Inhibition of Neurogenesis
- (2010) Valeria Kaltezioti et al. PLOS BIOLOGY
- NKX2-5 Regulates the Expression of β-Catenin and GATA4 in Ventricular Myocytes
- (2009) Ali M. Riazi et al. PLoS One
- Transcription Factor PROX1 Induces Colon Cancer Progression by Promoting the Transition from Benign to Highly Dysplastic Phenotype
- (2008) Tatiana V. Petrova et al. CANCER CELL
- Wnt Signaling in Liver Cancer
- (2008) Yutaka Takigawa et al. CURRENT DRUG TARGETS
- Prox1 maintains muscle structure and growth in the developing heart
- (2008) C. A. Risebro et al. DEVELOPMENT
- Prospero-related homeobox 1 and liver receptor homolog 1 coordinately regulate long-term proliferation of murine fetal hepatoblasts
- (2008) Akihide Kamiya et al. HEPATOLOGY
- High Expression of Macrophage Colony-Stimulating Factor in Peritumoral Liver Tissue Is Associated With Poor Survival After Curative Resection of Hepatocellular Carcinoma
- (2008) Xiao-Dong Zhu et al. JOURNAL OF CLINICAL ONCOLOGY
- Sorafenib in Advanced Hepatocellular Carcinoma
- (2008) Josep M. Llovet et al. NEW ENGLAND JOURNAL OF MEDICINE
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