Design of an EGFR-targeting toxin for photochemical delivery: in vitro and in vivo selectivity and efficacy

Photochemical internalization of tumor-targeted protein toxins

(2015) Anette Weyergang et al.   LASERS IN SURGERY AND MEDICINE

Photochemical internalization augments tumor vascular cytotoxicity and specificity of VEGF121/rGel fusion toxin

(2014) Anette Weyergang et al.   JOURNAL OF CONTROLLED RELEASE

Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome

(2014) Bente Bull-Hansen et al.   JOURNAL OF CONTROLLED RELEASE

The quest to overcome resistance to EGFR-targeted therapies in cancer

(2013) Curtis R Chong et al.   NATURE MEDICINE

Vascular endothelial cells as targets for photochemical internalization (PCI)

(2013) Marie Vikdal et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Sustained EKR inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy

(2012) Anette Weyergang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mechanisms of acquired resistance to targeted cancer therapies

(2012) Mark R Lackner et al.   Future Oncology

In vitro and in vivo anti-tumor activities of anti-EGFR single-chain variable fragment fused with recombinant gelonin toxin

(2012) Xikun Zhou et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Single-Chain Antibody-Based Immunotoxins Targeting Her2/neu: Design Optimization and Impact of Affinity on Antitumor Efficacy and Off-Target Toxicity

(2011) Y. Cao et al.   MOLECULAR CANCER THERAPEUTICS

Development and Characterization of a Potent Immunoconjugate Targeting the Fn14 Receptor on Solid Tumor Cells

(2011) H. Zhou et al.   MOLECULAR CANCER THERAPEUTICS

Disulfonated tetraphenyl chlorin (TPCS2a), a novel photosensitizer developed for clinical utilization of photochemical internalization

(2011) Kristian Berg et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Squamous cell carcinoma of the head and neck: EHNS-ESMO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2010) V. Gregoire et al.   ANNALS OF ONCOLOGY

Assessing autophagy in the context of photodynamic therapy

(2010) John J. Reiners et al.   Autophagy

Acquired resistance to cetuximab is mediated by increased PTEN instability and leads cross-resistance to gefitinib in HCC827 NSCLC cells

(2010) Sun Mi Kim et al.   CANCER LETTERS

Convergent Potency of Internalized Gelonin Immunotoxins across Varied Cell Lines, Antigens, and Targeting Moieties

(2010) Christopher M. Pirie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Photochemical internalization provides time- and space-controlled endolysosomal escape of therapeutic molecules

(2010) Pål Kristian Selbo et al.   JOURNAL OF CONTROLLED RELEASE

Construction and Characterization of Novel, Recombinant Immunotoxins Targeting the Her2/neu Oncogene Product: In vitro and In vivo Studies

(2009) Y. Cao et al.   CANCER RESEARCH

Multi-Modality Therapeutics with Potent Anti-Tumor Effects: Photochemical Internalization Enhances Delivery of the Fusion Toxin scFvMEL/rGel

(2009) Pål K. Selbo et al.   PLoS One

Antitumor activity of fibroblast growth factor receptor 3-specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis

(2008) J. L. Martinez-Torrecuadrada et al.   MOLECULAR CANCER THERAPEUTICS

Photodynamic therapy with an endocytically located photosensitizer cause a rapid activation of the mitogen-activated protein kinases extracellular signal-regulated kinase, p38, and c-Jun NH2 terminal kinase with opposing effects on cell survival

(2008) Anette Weyergang et al.   MOLECULAR CANCER THERAPEUTICS

EGFR Antagonists in Cancer Treatment

(2008) Fortunato Ciardiello et al.   NEW ENGLAND JOURNAL OF MEDICINE

Photochemical Internalization of Bleomycin is Superior to Photodynamic Therapy Due to the Therapeutic Effect in the Tumor Periphery

(2008) Ole-Jacob Norum et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Chromosomal imbalances in oral squamous cell carcinoma: Examination of 31 cell lines and review of the literature

(2007) Christa Lese Martin et al.   ORAL ONCOLOGY