PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components

(2014) Constance Alabert et al.   NATURE CELL BIOLOGY

Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks

(2014) François Aymard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of Early Replicating Fragile Sites that Contribute to Genome Instability

(2013) Jacqueline H. Barlow et al.   CELL

ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

(2013) Luis Ignacio Toledo et al.   CELL

Early replication fragile sites: where replication–transcription collisions cause genetic instability

(2013) Oliver Mortusewicz et al.   EMBO JOURNAL

Bacteriophage T5 Encodes a Homolog of the Eukaryotic Transcription Coactivator PC4 Implicated in Recombination-Dependent DNA Replication

(2013) Birthe Steigemann et al.   JOURNAL OF MOLECULAR BIOLOGY

Differential Requirement for SUB1 in Chromosomal and Plasmid Double-Strand DNA Break Repair

(2013) Lijian Yu et al.   PLoS One

Creating localized DNA double-strand breaks with microirradiation

(2011) Keiji Suzuki et al.   Nature Protocols

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

The multi-replication protein A (RPA) system - a new perspective

(2009) Kengo Sakaguchi et al.   FEBS Journal

Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress

(2009) V. M. Vassin et al.   JOURNAL OF CELL SCIENCE

Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites

(2008) Oliver Mortusewicz et al.   JOURNAL OF CELL BIOLOGY

Human Transcriptional Coactivator PC4 Stimulates DNA End Joining and Activates DSB Repair Activity

(2008) Kiran Batta et al.   JOURNAL OF MOLECULAR BIOLOGY