Spontaneous tumor development in bone marrow-rescued DNA-PKcs3A/3A mice due to dysfunction of telomere leading strand deprotection

Differential Phosphorylation of DNA-PKcs Regulates the Interplay between End-Processing and End-Ligation during Nonhomologous End-Joining

(2015) Wenxia Jiang et al.   MOLECULAR CELL

DNA-PKcs phosphorylates hnRNP-A1 to facilitate the RPA-to-POT1 switch and telomere capping after replication

(2015) Jiangdong Sui et al.   NUCLEIC ACIDS RESEARCH

DNA-PKcs-interacting protein KIP binding to TRF2 is required for the maintenance of functional telomeres

(2014) Prabhat Khadka et al.   BIOCHEMICAL JOURNAL

Mitosis Inhibits DNA Double-Strand Break Repair to Guard Against Telomere Fusions

(2014) A. Orthwein et al.   SCIENCE

The DNA damage response during mitosis

(2013) Anne Margriet Heijink et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Early and late steps in telomere overhang processing in normal human cells: the position of the final RNA primer drives telomere shortening

(2012) T. T. Chow et al.   GENES & DEVELOPMENT

A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest

(2012) Makoto T Hayashi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair

(2011) Shichuan Zhang et al.   JOURNAL OF CELL BIOLOGY

TRF2/RAP1 and DNA–PK mediate a double protection against joining at telomeric ends

(2010) Oriane Bombarde et al.   EMBO JOURNAL

Recent progress in dyskeratosis congenita

(2010) Nobuhiro Nishio et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

DNA damage signaling in response to double-strand breaks during mitosis

(2010) Simona Giunta et al.   JOURNAL OF CELL BIOLOGY

Apollo Contributes to G Overhang Maintenance and Protects Leading-End Telomeres

(2010) Peng Wu et al.   MOLECULAR CELL

Telomere Dysfunction and DNA-PKcs Deficiency: Characterization and Consequence

(2009) E. S. Williams et al.   CANCER RESEARCH

Telomere Extension Occurs at Most Chromosome Ends and Is Uncoupled from Fill-In in Human Cancer Cells

(2009) Yong Zhao et al.   CELL

Ku and DNA-dependent Protein Kinase Dynamic Conformations and Assembly Regulate DNA Binding and the Initial Non-homologous End Joining Complex

(2009) Michal Hammel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ku86 represses lethal telomere deletion events in human somatic cells

(2009) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutational Analysis of Thirty-two Double-Strand DNA Break Repair Genes in Breast and Pancreatic Cancers

(2008) X. Wang et al.   CANCER RESEARCH

Engineered telomere degradation models dyskeratosis congenita

(2008) D. Hockemeyer et al.   GENES & DEVELOPMENT

Pot1b Deletion and Telomerase Haploinsufficiency in Mice Initiate an ATR-Dependent DNA Damage Response and Elicit Phenotypes Resembling Dyskeratosis Congenita

(2008) H. He et al.   MOLECULAR AND CELLULAR BIOLOGY

The Catalytic Subunit of DNA-Dependent Protein Kinase Regulates Proliferation, Telomere Length, and Genomic Stability in Human Somatic Cells

(2008) B. L. Ruis et al.   MOLECULAR AND CELLULAR BIOLOGY

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

(2008) Kelly A McGowan et al.   NATURE GENETICS