Three-dimensional microenvironment confers enhanced sensitivity to doxorubicin by reducing p53-dependent induction of autophagy

Detachment-induced autophagy duringanoikisand lumen formation in epithelial acini

(2014) Jayanta Debnath   Autophagy

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(2014) Ezgi Tasdemir et al.   Autophagy

STAT3-Mediated Autophagy Dependence Identifies Subtypes of Breast Cancer Where Autophagy Inhibition Can Be Efficacious

(2014) P. Maycotte et al.   CANCER RESEARCH

Revisiting p53 for cancer-specific chemo- and radiotherapy

(2014) Jason M Beckta et al.   CELL CYCLE

Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome

(2014) Annabel Quinet et al.   DNA REPAIR

p53 in breast cancer subtypes and new insights into response to chemotherapy

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Autophagy Inhibition Sensitizes Colon Cancer Cells to Antiangiogenic and Cytotoxic Therapy

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The relative roles of DNA damage induced by UVA irradiation in human cells

(2013) Barbara Cortat et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Overexpression of Atg5 in mice activates autophagy and extends lifespan

(2013) Jong-Ok Pyo et al.   Nature Communications

TGF-β1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cells

(2012) Luciana R Gomes et al.   BMC CANCER

Epirubicin: Is it like doxorubicin in breast cancer? A clinical review

(2012) Mustafa Khasraw et al.   BREAST

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(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

p53-Mediated Senescence Impairs the Apoptotic Response to Chemotherapy and Clinical Outcome in Breast Cancer

(2012) James G. Jackson et al.   CANCER CELL

The Inhibition of Autophagy Sensitises Colon Cancer Cells with Wild-Type p53 but Not Mutant p53 to Topotecan Treatment

(2012) Dan-Dan Li et al.   PLoS One

Autophagy inhibition plays the synergetic killing roles with radiation in the multi-drug resistant SKVCR ovarian cancer cells

(2012) Bing Liang et al.   Radiation Oncology

Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development

(2011) Wei-Liang Sun et al.   Autophagy

Suppression of autophagy sensitizes multidrug resistant cells towards Src tyrosine kinase specific inhibitor PP2

(2011) Jun-Ho Ahn et al.   CANCER LETTERS

Both XPA and DNA polymerase eta are necessary for the repair of doxorubicin-induced DNA lesions

(2011) Maria Carolina S. Moraes et al.   CANCER LETTERS

Autophagy in the Cellular Energetic Balance

(2011) Rajat Singh et al.   Cell Metabolism

Principles and Current Strategies for Targeting Autophagy for Cancer Treatment

(2011) R. K. Amaravadi et al.   CLINICAL CANCER RESEARCH

Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib - the role of extracellular signal-regulated kinase counteraction

(2011) Irena Manov et al.   FEBS Journal

The dynamic nature of autophagy in cancer

(2011) A. C. Kimmelman   GENES & DEVELOPMENT

Downregulation of VRK1 by p53 in Response to DNA Damage Is Mediated by the Autophagic Pathway

(2011) Alberto Valbuena et al.   PLoS One

p53 Regulates Oxidative Stress-Mediated Retrograde Signaling: A Novel Mechanism for Chemotherapy-Induced Cardiac Injury

(2011) Joyce M. Velez et al.   PLoS One

Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53

(2011) Saeid Ghavami et al.   PLoS One

MCF-7 Cells as a Three-Dimensional Model for the Study of Human Breast Cancer

(2011) Jônatas Bussador do Amaral et al.   TISSUE ENGINEERING PART C-METHODS

Regulation of autophagy by extracellular matrix glycoproteins in HeLa cells

(2010) Véronique Tuloup-Minguez et al.   Autophagy

Doxorubicin as a Molecular Nanotheranostic Agent: Effect of Doxorubicin Encapsulation in Micelles or Nanoemulsions on the Ultrasound-Mediated Intracellular Delivery and Nuclear Trafficking

(2010) Praveena Mohan et al.   MOLECULAR PHARMACEUTICS

p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation

(2010) R. Scherz-Shouval et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Superoxide is the major reactive oxygen species regulating autophagy

(2009) Y Chen et al.   CELL DEATH AND DIFFERENTIATION

Three-Dimensional Overlay Culture Models of Human Breast Cancer Reveal a Critical Sensitivity to Mitogen-Activated Protein Kinase Kinase Inhibitors

(2009) Q. Li et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Extracellular matrix regulation of autophagy

(2008) Rebecca Lock et al.   CURRENT OPINION IN CELL BIOLOGY

Caspase‐3 enhances lung metastasis and cell migration in a protease‐independent mechanism through the ERK pathway

(2008) Yu‐Jung Cheng et al.   INTERNATIONAL JOURNAL OF CANCER

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

(2007) Christopher Fung et al.   MOLECULAR BIOLOGY OF THE CELL