SLC29A1 single nucleotide polymorphisms as independent prognostic predictors for survival of patients with acute myeloid leukemia: an in vitro study

TP53mutations andMDM2SNP309identify subgroups of AML patients with impaired outcome

(2014) Ingrid Jakobsen Falk et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Decreased survival in normal karyotype AML with single-nucleotide polymorphisms in genes encoding the AraC metabolizing enzymes cytidine deaminase and 5′-nucleotidase

(2013) Ingrid Jakobsen Falk et al.   AMERICAN JOURNAL OF HEMATOLOGY

Clofarabine, idarubicin, and cytarabine (CIA) as frontline therapy for patients ≤60 years with newly diagnosed acute myeloid leukemia

(2013) Aziz Nazha et al.   AMERICAN JOURNAL OF HEMATOLOGY

Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients

(2013) E. R. Gamazon et al.   BLOOD

Increased CDA Expression/Activity in Males Contributes to Decreased Cytidine Analog Half-Life and Likely Contributes to Worse Outcomes with 5-Azacytidine or Decitabine Therapy

(2013) R. Z. Mahfouz et al.   CLINICAL CANCER RESEARCH

High-Dose Cytarabine in Induction Treatment Improves the Outcome of Adult Patients Younger Than Age 46 Years With Acute Myeloid Leukemia: Results of the EORTC-GIMEMA AML-12 Trial

(2013) Roelof Willemze et al.   JOURNAL OF CLINICAL ONCOLOGY

Chemomodulation of sequential high-dose cytarabine by fludarabine in relapsed or refractory acute myeloid leukemia: a randomized trial of the AMLCG

(2013) M Fiegl et al.   LEUKEMIA

RRM1andRRM2pharmacogenetics: association with phenotypes in HapMap cell lines and acute myeloid leukemia patients

(2013) Xueyuan Cao et al.   PHARMACOGENOMICS

Combined interaction of multi-locus genetic polymorphisms in cytarabine arabinoside metabolic pathway on clinical outcomes in adult acute myeloid leukaemia (AML) patients

(2012) Kyung Im Kim et al.   EUROPEAN JOURNAL OF CANCER

CYP1A1 MspI polymorphism and acute myeloid leukemia risk: meta-analyses based on 5018 subjects

(2012) Wenlei Zhuo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cytidine deaminase genetic variants influence RNA expression and cytarabine cytotoxicity in acute myeloid leukemia

(2012) Ajay Abraham et al.   PHARMACOGENOMICS

Long term cultured HL-60 cells are intrinsically resistant to Ara-C through high CDA activity

(2011) Jinqing Tang   Frontiers in Bioscience-Landmark

An accumulation of cytogenetic and molecular genetic events characterizes the progression from MDS to secondary AML: an analysis of 38 paired samples analyzed by cytogenetics, molecular mutation analysis and SNP microarray profiling

(2011) J Flach et al.   LEUKEMIA

Fludarabine and cytarabine in patients with acute myeloid leukemia refractory to two different courses of front-line chemotherapy

(2011) Dhaval R. Mehta et al.   LEUKEMIA RESEARCH

Genetic Effects and Modifiers of Radiotherapy and Chemotherapy on Survival in Pancreatic Cancer

(2011) Hongmei Zeng et al.   PANCREAS

Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer

(2011) Liang Li et al.   Pharmacogenetics and Genomics

New Prognostic Markers in Acute Myeloid Leukemia: Perspective from the Clinic

(2011) J. M. Foran   Hematology-American Society of Hematology Education Program

FLT3-ITD induces ara-C resistance in myeloid leukemic cells through the repression of the ENT1 expression

(2009) Guilan Jin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intracellular cytarabine triphosphate production correlates to deoxycytidine kinase/cytosolic 5′-nucleotidase II expression ratio in primary acute myeloid leukemia cells

(2009) Takahiro Yamauchi et al.   BIOCHEMICAL PHARMACOLOGY

Acute Myeloid Leukemia With Translocation (8;21) or Inversion (16) in Elderly Patients Treated With Conventional Chemotherapy: A Collaborative Study of the French CBF-AML Intergroup

(2009) Thomas Prébet et al.   JOURNAL OF CLINICAL ONCOLOGY

SNP analyses in cytarabine metabolizing enzymes in AML patients and their impact on treatment response and patient survival: identification of CDA SNP C-451T as an independent prognostic parameter for survival

(2009) U Mahlknecht et al.   LEUKEMIA

Influence of Friedreich Ataxia GAA Noncoding Repeat Expansions on Pre-mRNA Processing

(2008) Marco Baralle et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Two Distinct Molecular Mechanisms Underlying Cytarabine Resistance in Human Leukemic Cells

(2008) J. Cai et al.   CANCER RESEARCH