FGFR-1 amplification in metastatic lymph-nodal and haematogenous lobular breast carcinoma

The fibroblast growth factor receptor 1 (FGFR1), a marker of response to chemoradiotherapy in breast cancer?

(2012) Carole Massabeau et al.   BREAST CANCER RESEARCH AND TREATMENT

AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family

(2012) P. R. Gavine et al.   CANCER RESEARCH

Fibroblast growth factor receptors in breast cancer: expression, downstream effects, and possible drug targets

(2012) M Tenhagen et al.   ENDOCRINE-RELATED CANCER

Discordant Cellular Response to Presurgical Letrozole in Bilateral Synchronous ER+ Breast Cancers with a KRAS Mutation or FGFR1 Gene Amplification

(2012) J. M. Balko et al.   MOLECULAR CANCER THERAPEUTICS

Ponatinib (AP24534), a Multitargeted Pan-FGFR Inhibitor with Activity in Multiple FGFR-Amplified or Mutated Cancer Models

(2012) J. M. Gozgit et al.   MOLECULAR CANCER THERAPEUTICS

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Current and emerging targeted therapies for metastatic breast cancer

(2011) Edith A. Perez et al.   CANCER

High-resolution genomic analysis of the 11q13 amplicon in breast cancers identifies synergy with 8p12 amplification, involving the mTOR targets S6K2 and 4EBP1

(2011) Elin Karlsson et al.   GENES CHROMOSOMES & CANCER

Classical lobular breast carcinoma consistently lacks topoisomerase-IIα gene amplification: implications for the tailored use of anthracycline-based chemotherapies

(2011) Eleonora Brunello et al.   HISTOPATHOLOGY

Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer

(2011) Amit Dutt et al.   PLoS One

FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer

(2010) N. Turner et al.   CANCER RESEARCH

Experimental treatment of oestrogen receptor (ER) positive breast cancer with tamoxifen and brivanib alaninate, a VEGFR-2/FGFR-1 kinase inhibitor: A potential clinical application of angiogenesis inhibitors

(2010) Roshani R. Patel et al.   EUROPEAN JOURNAL OF CANCER

Amplification of fibroblast growth factor receptor-1 in breast cancer and the effects of brivanib alaninate

(2009) Christine Y. Shiang et al.   BREAST CANCER RESEARCH AND TREATMENT

Fibroblast Growth Factor Receptor 1-Transformed Mammary Epithelial Cells Are Dependent on RSK Activity for Growth and Survival

(2009) W. Xian et al.   CANCER RESEARCH

Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis

(2009) S S Kwek et al.   ONCOGENE

HER-2/neu Assessment in Breast Cancer Using the Original FDA and New ASCO/CAP Guideline Recommendations

(2008) Matteo Brunelli et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY