Fitness landscapes emerging from pharmacodynamic functions in the evolution of multidrug resistance

Patterns of Epistasis between Beneficial Mutations in an Antibiotic Resistance Gene

(2013) Martijn F. Schenk et al.   MOLECULAR BIOLOGY AND EVOLUTION

Designing Antibiotic Cycling Strategies by Determining and Understanding Local Adaptive Landscapes

(2013) Christiane P. Goulart et al.   PLoS One

The Pharmaco –, Population and Evolutionary Dynamics of Multi-drug Therapy: Experiments with S. aureus and E. coli and Computer Simulations

(2013) Peter Ankomah et al.   PLoS Pathogens

The Effect of Bacterial Recombination on Adaptation on Fitness Landscapes with Limited Peak Accessibility

(2012) Danesh Moradigaravand et al.   PLoS Computational Biology

Two-Drug Antimicrobial Chemotherapy: A Mathematical Model and Experiments with Mycobacterium marinum

(2012) Peter Ankomah et al.   PLoS Pathogens

EPISTASIS BUFFERS THE FITNESS EFFECTS OF RIFAMPICIN- RESISTANCE MUTATIONS IN PSEUDOMONAS AERUGINOSA

(2011) Alex R. Hall et al.   EVOLUTION

Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs

(2011) P. E. Almeida Da Silva et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The causes of epistasis

(2011) J. A. G. M. de Visser et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Pervasive Sign Epistasis between Conjugative Plasmids and Drug-Resistance Chromosomal Mutations

(2011) Rui F. Silva et al.   PLoS Genetics

Selection of Resistant Bacteria at Very Low Antibiotic Concentrations

(2011) Erik Gullberg et al.   PLoS Pathogens

Compensation of Fitness Costs and Reversibility of Antibiotic Resistance Mutations

(2010) P. Schulz zur Wiesch et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Alarming β-lactamase-mediated resistance in multidrug-resistant Enterobacteriaceae

(2010) Karen Bush   CURRENT OPINION IN MICROBIOLOGY

Diminishing Returns From Beneficial Mutations and Pervasive Epistasis Shape the Fitness Landscape for Rifampicin Resistance in Pseudomonas aeruginosa

(2010) R. C. MacLean et al.   GENETICS

NDM-1 — A Cause for Worldwide Concern

(2010) Robert C. Moellering   NEW ENGLAND JOURNAL OF MEDICINE

Exploring the Effect of Sex on Empirical Fitness Landscapes

(2009) J. Arjan G. M. de Visser et al.   AMERICAN NATURALIST

Multidrug Resistance in Bacteria

(2009) Hiroshi Nikaido   Annual Review of Biochemistry

Characterization of a New Metallo- -Lactamase Gene, blaNDM-1, and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India

(2009) D. Yong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Drug interactions and the evolution of antibiotic resistance

(2009) Pamela J. Yeh et al.   NATURE REVIEWS MICROBIOLOGY

Waves of resistance: Staphylococcus aureus in the antibiotic era

(2009) Henry F. Chambers et al.   NATURE REVIEWS MICROBIOLOGY

Predicting the Evolution of Sex on Complex Fitness Landscapes

(2009) Dusan Misevic et al.   PLoS Computational Biology

Positive Epistasis Drives the Acquisition of Multidrug Resistance

(2009) Sandra Trindade et al.   PLoS Genetics