Article
Surgery
E. Hope Weissler, Bradley G. Hammill, Jenna L. Armstrong, Andrew M. Vekstein, Parth Chodavadia, Chandler A. Long, Matthew Roe, G. Chad Hughes
Summary: Through analyzing the reports related to thoracic endovascular aortic repair (TEVAR) in the FDA's Manufacturer and User Facility Device Experience (MAUDE) database, it was found that there is an association between the Medtronic Valiant device and type IIIb endoleaks, and this association can be traced back to 2013. The study also discovered that all type IIIb endoleaks occurred in patients who received TEVAR with devices containing sutured on woven fabric.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Article
Surgery
Fabio Verzini, Enrico Cieri, Andrea Kahlberg, Yaron Sternbach, Robin Heijmen, Kenneth Ouriel, Sam Robaina, Ali Azizzadeh
Summary: Patients in the Valiant Evo clinical trials showed positive short-term outcomes, but late structural failures, such as type IIIb endoleaks and stent fractures, were recently discovered in some patients. It is important to closely monitor imaging patterns associated with these failures and promptly identify and treat them to prevent adverse events like aortic rupture.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Surgery
Michele Piazza, Francesco Squizzato, Andrea Xodo, Gianna Saviane, Edoardo Forcella, Chiara Dal Pont, Franco Grego, Michele Antonello
Summary: The study aimed to determine the optimal and safest proximal sealing length during thoracic endovascular aortic repair (TEVAR). For type II and III aortic arches, a proximal sealing length of 25-30mm may be required for a safe and durable procedure.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Sven R. Hauck, Alexander Kupferthaler, Maximilian Kern, Herve Rousseau, Ciro Ferrer, Shinichi Iwakoshi, Shoji Sakaguchi, Marie-Elisabeth Stelzmuller, Marek Ehrlich, Christian Loewe, Martin A. Funovics
Summary: This study compared the results of two commercially available devices for branched thoracic endovascular aortic repair and fenestrated thoracic endovascular aortic repair. The results showed that both methods had excellent technical success and acceptable complication rates, but branched repair tended to have higher stroke rates. Meanwhile, fenestrated repair had a wider range of applicability.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Peripheral Vascular Disease
Stefano Gennai, Nicola Leone, Luigi A. Maria Bartolotti, Tea Covic, Antonio Lauricella, Francesco Andreoli, Giuseppe Saitta, Roberto Silingardi
Summary: This study compared endoleak outcomes after thoracic endovascular aneurysm repair with different stent-graft generations over long-term follow-up. Endoleak incidence significantly decreased over evolving stent-grafts generations, with newer generations showing better long-term outcomes. Ongoing updates are necessary to confirm the reliability and durability of these newer stent-graft generations.
Article
Surgery
Fadi Taher, Markus Plimon, Corinna Walter, Gabriel Weiss, Miriam Kliewer, Afshin Assadian, Juergen Falkensammer
Summary: This study evaluates the technical outcome of fenestrated endovascular aortic repair (FEVAR) after prior EVAR and identifies factors that may influence complication rates. The results show that the technical failure rate significantly decreases in FEVAR after EVAR patients, and the occurrence of primary unconnected fenestrations is similar to primary FEVAR. However, the operating time is longer. FEVAR can be a feasible and safe treatment option for patients with progression of aortic disease or type Ia endoleak after EVAR.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Article
Surgery
Efthymios Beropoulis, Stefano Fazzini, Martin Austermann, Giovanni B. Torsello, Sarah Damerau, Giovanni Federico Torsello
Summary: A retrospective analysis of 44 patients treated with the Zenith Alpha thoracic stent-graft showed ongoing clinical success at 84% over a 5-year period, with few complications observed.
JOURNAL OF ENDOVASCULAR THERAPY
(2021)
Article
Engineering, Biomedical
Jakub Kwiecinski, Christopher P. Cheng, Raman Uberoi, Mohammed Hadi, Philipp Hempel, Christoph Degel, Zhong You
Summary: This study investigated the loading and deformation behavior of parallel endografts in chimney thoracic endovascular aortic repair (ch-TEVAR) configurations. It found that different main endograft manufacturers and chimney graft types could affect the radial loads and mechanical deformations, with parallel endografting increasing the radial loads.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Cardiac & Cardiovascular Systems
Kota Shukuzawa, Tomoya Fujii, Makoto Sumi, Junya Kozaki, Mitsuo Umezu, Takao Ohki, Kiyotaka Iwasaki
Summary: This study aimed to analyze the relationship between aortic surface irregularity and type 1 endoleak (T1EL) after thoracic endovascular repair using the Najuta fenestrated stent graft. The study found that patients with a continuously malapposed region of >1mm had a significantly lower rate of T1EL occurrence compared to those without.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Surgery
Enrico Maria Marone, Giulia Marazzi, Chiara Brioschi, Luigi Federico Rinaldi
Summary: This study aims to show the long-term outcomes of endovascular aortic repair using Treo endograft in treating standard and hostile abdominal aortic aneurysms (AAAs). The results after 5 years of follow-up demonstrate that Treo endograft is effective in treating AAAs with hostile anatomy, with satisfactory aneurysm sac shrinkage rate.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Article
Medicine, General & Internal
Tomoaki Kudo, Toru Kuratani, Yoshiki Sawa, Shigeru Miyagawa
Summary: This study compared the outcomes of bTEVAR and hTEVAR in landing zone 0 for the treatment of aortic arch diseases. The study found no significant differences in in-hospital mortality, aorta-related deaths, and aortic reintervention rates between the bTEVAR and hTEVAR groups. However, the bTEVAR group had significantly shorter operative time and length of hospital stay compared to the hTEVAR group.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Surgery
Stefano Gennai, Nicola Leone, Luigi A. M. Bartolotti, Francesco Andreoli, Ginevra Pizzarelli, Roberto Silingardi
Summary: This study analyzed the learning curve of a widely used stent-graft for thoracic endovascular repair (TEVAR) by examining procedural variables and their impact on long-term outcomes. The results showed that the learning curve was reached after 10 patients and the secondary outcomes improved significantly with experience. The Relay stent-graft demonstrated satisfactory long-term results with a short learning curve in a high-volume endovascular center.
JOURNAL OF ENDOVASCULAR THERAPY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ge Hu, Ning Ding, Zhiwei Wang, Zhengyu Jin
Summary: This study explores the feasibility of using unenhanced CT images for endoleak detection in AAA after EVAR. The results show that unenhanced CT has high sensitivity and specificity and can help detect endoleaks in AAA. This is of great importance for patients who cannot use contrast media.
EUROPEAN RADIOLOGY
(2023)
Article
Surgery
Sai Divya Yadavalli, Winona W. Wu, Vinamr Rastogi, Jorge L. Gomez-Mayorga, Yoel Solomon, Douglas W. Jones, Salvatore T. Scali, Hence J. M. Verhagen, Marc L. Schermerhorn
Summary: TEVAR for M-TAA after previous EVAR, especially in octogenarians, is associated with higher perioperative and 5-year mortality. TEVAR after previous OAR showed no notable differences compared to primary TEVAR.
JOURNAL OF VASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Xiang Kong, Peng Ruan, Jiquan Yu, Tianshu Chu, Lei Gao, Hui Jiang, Jianjun Ge
Summary: This study evaluated the efficacy of a novel unibody single-branched stent graft for zone 2 TEVAR. The results showed that the stent was safe and effective in the short and medium term, providing an adequate proximal landing zone.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Maria Melendo-Viu, Alvaro Marchan-Lopez, Carmen Jimenez-Lopez Guarch, Sergio Raposeiras Roubin, Emad Abu-Assi, Rocio Tello Meneses, Fernando Arribas Ynsaurriaga, Adrian V. Hernandez, Hector Bueno
Summary: Acute idiopathic pericarditis (AIP) is a benign inflammatory condition with high recurrence rates. NSAIDs and colchicine are recommended therapies.
TRENDS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Gastroenterology & Hepatology
Phuc Le, Julia Yang Payne, Lu Zhang, Abhishek Deshpande, Michael B. Rothberg, Naim Alkhouri, William Herman, Adrian V. Hernandez, Mary Schleicher, Wen Ye, Srinivasan Dasarathy
Summary: We conducted a meta-analysis on the rates of progression and regression in nonalcoholic fatty liver disease (NAFLD) patients. The results showed that the frequency of progression to nonalcoholic steatohepatitis (NASH) was higher than the rate of regression. The rates of fibrosis progression were similar across baseline stages, but patients with advanced fibrosis were more likely to regress than those with mild fibrosis.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Review
Medicine, General & Internal
Adrian V. Hernandez, Vinay Pasupuleti, Nancy Scarpelli, Jack Malespini, Maciej Banach, Agata M. Bielecka-Dabrowa
Summary: This study assessed the benefits and harms of Sacubitril/valsartan (S/V) compared to ACEI or ARB in heart failure patients. The results showed that S/V reduced HF hospitalizations by 20%, CV mortality by 14%, and all-cause mortality by 11% compared to ACEI or ARB. However, S/V had negative effects on renal function and increased hypotension events.
ARCHIVES OF MEDICAL SCIENCE
(2023)
Review
Immunology
Leila S. Hojat, Elie A. Saade, Adrian Hernandez, Curtis J. Donskey, Abhishek Deshpande
Summary: This systematic review and meta-analysis examined the use of clinical decision support (CDS) in the diagnosis of urinary tract infection (UTI). The findings showed that CDS was effective in reducing urine culture rates, with significant results.
OPEN FORUM INFECTIOUS DISEASES
(2023)
Review
Cardiac & Cardiovascular Systems
Carlos Diaz-Arocutipa, Jack Denegri-Galvan, Lourdes Vicent, Marcos Pariona, Mamas A. Mamas, Adrian V. Hernandez
Summary: We evaluated the effects of hypertonic saline solution (HSS) plus furosemide compared to furosemide alone in patients with acute decompensated heart failure (ADHF). Ten randomized controlled trials involving 3013 patients were included in our study. HSS plus furosemide significantly reduced hospital stay, weight, serum creatinine, and type-B natriuretic peptide compared to furosemide alone. HSS plus furosemide also significantly increased urine output, serum Na+, and urine Na+ compared to furosemide alone.
CLINICAL CARDIOLOGY
(2023)
Review
Medicine, General & Internal
Frank Mayta-Tovalino, Carlos Diaz-Arocutipa, Alejandro Piscoya, Adrian V. V. Hernandez
Summary: In overweight or obese patients, receiving probiotics treatment led to improvements in BMI, weight, and low-density lipoprotein levels compared to the control group. However, probiotics had no significant effect on blood pressure, glucose, high-density lipoprotein, or triglycerides.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
German Valenzuela-Rodriguez, Carlos Diaz-Arocutipa, Jaime A. A. Collins, Adrian V. V. Hernandez
Summary: In HIV patients, the use of integrase inhibitor-based therapy was found to result in a small increase in weight and small decreases in lipid serum levels compared to other antiretroviral therapies.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Farley E. Salazar-Valdivia, Valeria A. Valdez-Cornejo, Juan R. Ulloque-Badaracco, Enrique A. Hernandez-Bustamante, Esteban A. Alarcon-Braga, Melany D. Mosquera-Rojas, Diana P. Garrido-Matta, Percy Herrera-Anazco, Vicente A. Benites-Zapata, Adrian V. Hernandez
Summary: The systemic immune-inflammation index (SIII) has been studied as a marker for various urologic cancers, including testicular cancer. This systematic review analyzed observational studies from five databases and found that high SIII values were associated with worse overall survival (OS) and progression-free survival (PFS) in testicular cancer patients. A sensitivity analysis was performed to assess the risk of bias in the studies. However, further primary studies are recommended to strengthen the evidence of SIII as a prognostic marker in testicular cancer.
Review
Dentistry, Oral Surgery & Medicine
Frank Mayta-Tovalino, Joshuan J. Barboza, Vinay Pasupuleti, Adrian V. Hernandez
Summary: This study systematically assessed the efficacy of tunnel technique (TUN) vs. coronally advanced flap (CAF) in the management of multiple gingival recession defects in adults. The results showed that there were no significant differences between TUN and CAF in terms of primary and secondary outcomes. The study emphasizes the need for more well-designed randomized controlled trials (RCTs) to further evaluate the effects of TUN vs. CAF in the treatment of multiple gingival recession defects.
INTERNATIONAL JOURNAL OF DENTISTRY
(2023)
Review
Public, Environmental & Occupational Health
William M. Patterson, Jesse Fajnzylber, Neil Nero, Adrian V. Hernandez, Abhishek Deshpande
Summary: This study aimed to systematically review the methodology, performance, and generalizability of diagnostic models for predicting the risk of healthcare-facility-onset (HO) Clostridioides difficile infection (CDI) in adult hospital inpatients. The quality and utility of these models remain uncertain, with most studies showing a high risk of bias. The most common predictors across all models were advanced age, receipt of high-risk antibiotics, history of hospitalization, and history of CDI.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Review
Endocrinology & Metabolism
Beatriz Melgar, Carlos Diaz-Arocutipa, Claudia Huerta-Rengifo, Alejandro Piscoya, Joshuan J. Barboza, Adrian V. Hernandez
Summary: A systematic review and meta-analysis found that vegetarian diets may lead to weight loss and reduced blood glucose levels in people with overweight and obesity compared to omnivorous diets. However, there was no significant impact on blood pressure or other metabolic and anthropometric outcomes. The quality of evidence for most outcomes was low. Larger randomized controlled trials are needed to further evaluate the effects of vegetarian diets in this population.
INTERNATIONAL JOURNAL OF OBESITY
(2023)
Article
Surgery
Lei Zhang, Wen-Ping Hu, Hao Zhang, Shi-Bo Xia, Hong-Fei Wang, Chao Song, Qing-Sheng Lu
Summary: The purpose of this study was to evaluate the necessity of inferior vena cava filter placement to prevent fatal pulmonary embolism and determine the risk factors of trapped embolus. The study found that lower limb fracture, pelvis surgery, and PMT + CDT were risk factors for trapped embolus. Elderly patients and those receiving CDT-only treatment do not need filter placement.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Review
Substance Abuse
Morica Hutchison, Beth S. Russell, Abigail Leander, Nathaniel Rickles, Derek Aguiar, Xiaomei S. Cong, Ofer Harel, Adrian V. Hernandez
Summary: This study systematically reviewed trends of adherence and retention in Medication Treatment for Opioid Use Disorders (MOUD) in the USA from 2011 to 2021. The findings showed an adherence rate of 56% across all studies, with the highest adherence rate observed in methadone treatment (73%). The retention rate varied among different study designs, with case series having a retention rate of 57%, cohorts of 47%, and RCTs of 70%. The most common barriers to treatment were younger age, comorbid diagnoses, daily attendance, lack of insurance, and transportation issues. The study highlights the importance of retention in care for MOUD treatment.
JOURNAL OF DRUG ISSUES
(2023)
Article
Gastroenterology & Hepatology
Harold Benites-Goni, Fernando Palacios-Salas, Andrea Carlin-Ronquillo, Carlos Diaz-Arocutipa, Alejandro Piscoya, Adrian V. Hernandez
Summary: ESD is the standard treatment for differentiated early gastric cancer, but its expanded indication for undifferentiated EGC is controversial. This study compared the efficacy and safety of ESD versus surgery in patients with undifferentiated EGC. Although ESD is associated with a higher risk of any recurrence, adjusted all-cause mortality is similar during follow-up. Overall complications were similar between ESD and surgery.
REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
(2023)
Review
Gastroenterology & Hepatology
Harold Benites-Goni, Fernando Palacios-Salas, Luis Marin-Calderon, Carlos Diaz-Arocutipa, Alejandro Piscoya, Adrian Hernandez
Summary: A systematic review found that the short-term outcomes of ESD for EGC in non-Asian countries are acceptable, with high rates of en bloc, R0, and curative resections, and low rates of postoperative complications.
ANNALS OF GASTROENTEROLOGY
(2023)