Review
Biochemistry & Molecular Biology
Avan Kader, Julia Brangsch, Jan O. Kaufmann, Jing Zhao, Dilyana B. Mangarova, Jana Moeckel, Lisa C. Adams, Ingolf Sack, Matthias Taupitz, Bernd Hamm, Marcus R. Makowski
Summary: This review summarizes recent developments in molecular imaging markers for magnetic resonance imaging of prostate cancer, aiming to improve the molecular characterization of the tumor and enable targeted therapies to suppress tumor growth or reduce tumor size in a non-invasive manner.
Review
Biology
Carla Contaldi, Vincenzo Montesarchio, Dario Catapano, Luigi Falco, Francesca Caputo, Carmine D'Aniello, Daniele Masarone, Giuseppe Pacileo
Summary: This article examines the intricate relationship between cancer therapy and the cardiovascular system, and explores the role of advanced multimodality imaging in monitoring patients before, during, and after cancer treatment. It provides a comprehensive understanding of the cardiovascular effects of different cancer therapy classes, and outlines the strengths and limitations of various imaging modalities.
Article
Biochemistry & Molecular Biology
Avan Kader, Jan O. Kaufmann, Dilyana B. Mangarova, Jana Moeckel, Lisa C. Adams, Julia Brangsch, Jennifer L. Heyl, Jing Zhao, Christine Verlemann, Uwe Karst, Federico Collettini, Timo A. Auer, Bernd Hamm, Marcus R. Makowski
Summary: The constant interactions between tumor cells and the extracellular matrix in prostate cancer influence its progression. Collagen fibers, as key components of the extracellular matrix, play important roles in tissue stiffness, growth, adhesion, proliferation, migration, invasion/metastasis, cell signaling, and immune recruitment of tumor cells. In this study, molecular magnetic resonance imaging (MRI) using a collagen-specific probe was used to explore the molecular marker in prostate cancer. The results showed that there was no significant signal difference between two different tumor volumes, but there was a significant difference in the signal intensity between the peripheral and central areas of the tumor, indicating higher collagen expression in the peripheral area. The MRI data were strongly correlated with the histological data and supported by elemental analysis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Oncology
Trinh Nguyen, Priya R. Bhosale, Lorena Cassia, Venkateswar Surabhi, Sanaz Javadi, Andrea Milbourne, Silvana C. Faria
Summary: With the increasing average age of pregnancy and the use of prenatal fetal noninvasive screening techniques, more cases of cancer are being diagnosed in pregnant women. This poses complex challenges in terms of imaging, diagnosis, staging, and treatment, requiring specialized interdisciplinary management. This report discusses the use of multimodality imaging and safety considerations, reviews current guidelines for ionizing radiation imaging techniques, and presents diagnostic imaging guidelines for common and uncommon cancers in pregnancy.
Article
Oncology
Juan Morote, Angel Borque-Fernando, Marina Triquell, Anna Celma, Lucas Regis, Richard Mast, Ines M. de Torres, Maria E. Semidey, Anna Santamaria, Jacques Planas, Luis M. Esteban, Enrique Trilla
Summary: The study confirmed that prostate magnetic resonance imaging (MRI) grades the aggressiveness of prostate cancer (PCa), with its rating significantly related to GG, surgical specimen pathology type, clinical stage, and biochemical recurrence risk after treatment of localized PCa.
Article
Radiology, Nuclear Medicine & Medical Imaging
Lei Hu, Da Wei Zhou, Cai Xia Fu, Thomas Benkert, Chun Yu Jiang, Rui Ting Li, Li Ming Wei, Jun Gong Zhao
Summary: The radiomics signatures based on zoomed diffusion-weighted imaging technology showed better diagnostic accuracy for prostate cancer compared to traditional full-field-of-view DWI technology. The mixed model performed the best in diagnosing PCa and guiding clinical interventions among the studied models.
EUROPEAN RADIOLOGY
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Trinh Nguyen, Akshya Gupta, Shweta Bhatt
Summary: Lymphomatous involvement of the genitourinary system, particularly the kidneys, is often underestimated and underreported on conventional diagnostic imaging. This is due to its variable imaging appearance and overlapping features with other conditions. By presenting a spectrum of typical and atypical appearances of renal lymphoma using multimodality imaging, this article highlights the importance of imaging in the detection, diagnosis, staging, and surveillance of patients with lymphoma.
INSIGHTS INTO IMAGING
(2022)
Article
Urology & Nephrology
Benjamin D. Besasie, Abhijit G. Sunnapwar, Feng Gao, Dean Troyer, Geoffrey D. Clarke, Hugh White, Peter T. Fox, Anders Dale, Allison Wheeler, Michael A. Liss
Summary: Restriction spectrum imaging-magnetic resonance imaging improves upgrading detection in active surveillance for prostate cancer, especially for predicting Gleason upgrading, by providing a noninvasive radiological biomarker.
JOURNAL OF UROLOGY
(2021)
Letter
Oncology
Amanda Khoo, Lydia Y. Liu, Taylor Y. Sadun, Amirali Salmasi, Aydin Pooli, Ely Felker, Kathleen E. Houlahan, Vladimir Ignatchenko, Steven S. Raman, Anthony E. Sisk, Robert E. Reiter, Paul C. Boutros, Thomas Kislinger
Summary: This study found that the tumors that are invisible on mpMRI closely resemble the histologically normal prostate, indicating that tumor visibility on mpMRI depends on the proteomic differences between the tumor and normal prostate.
JOURNAL OF HEMATOLOGY & ONCOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Valentina Mantegazza, Valentina Volpato, Paola Gripari, Sarah Ghulam Ali, Laura Fusini, Gianpiero Italiano, Manuela Muratori, Gianluca Pontone, Gloria Tamborini, Mauro Pepi
Summary: Mitral annular disjunction (MAD) is associated with mitral valve prolapse (MVP) and may lead to malignant ventricular arrhythmias. Different imaging techniques such as transthoracic echocardiography (TTE) and cardiac magnetic resonance (CMR) can be used for MAD identification and measurement, with an integrated approach being necessary for comprehensive assessment of patients with MVP and arrhythmia symptoms.
Article
Cardiac & Cardiovascular Systems
Nitin Malik, Monica Mukherjee, Katherine C. Wu, Stefan L. Zimmerman, Junzhen Zhan, Hugh Calkins, Cynthia A. James, Nisha A. Gilotra, Farooq H. Sheikh, Harikrishna Tandri, Shelby Kutty, Allison G. Hays
Summary: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare and heritable myocardial disease associated with serious cardiovascular complications and early cardiac sudden death. Multimodality imaging, including echocardiography and cardiac magnetic resonance imaging, plays a crucial role in the diagnosis and evaluation of ARVC. Echocardiography is a widely available and cost-effective technique, while cardiac magnetic resonance provides more comprehensive assessment of the structure and function. However, both imaging techniques have their limitations.
CIRCULATION-CARDIOVASCULAR IMAGING
(2022)
Review
Oncology
Haneyeh Shahbazian, Mohammad Mirza-Aghazadeh-Attari, Ali Borhani, Alireza Mohseni, Seyedeh Panid Madani, Golnoosh Ansari, Timothy M. Pawlik, Ihab R. Kamel
Summary: Hepatocellular carcinoma and intrahepatic cholangiocarcinoma are the two most common primary malignant tumors of the liver. This review discusses and outlines the similarities and variations in imaging characteristics that can help distinguish between these two primary tumors. Understanding the available imaging techniques would assist in differentiating these primary malignancies.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Sumit Gupta, Yin Ge, Amitoj Singh, Christoph Grani, Raymond Y. Kwong
Summary: Myocardial fibrosis is an important indicator of adverse outcomes in heart disease, and noninvasive imaging techniques play a key role in early detection and quantification of myocardial fibrosis, helping to improve the diagnosis and treatment of patients.
JACC-CARDIOVASCULAR IMAGING
(2021)
Review
Cardiac & Cardiovascular Systems
Christine Farrell, Aparna Balasubramanian, Allison G. Hays, Steven Hsu, Steven Rowe, Stefan L. Zimmerman, Paul M. Hassoun, Stephen C. Mathai, Monica Mukherjee
Summary: Pulmonary hypertension is a serious condition with high morbidity and mortality. Early identification and monitoring of the disease using multimodality imaging can improve outcomes and assess the severity of right ventricular dysfunction.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
M. Boschheidgen, L. Schimmoeller, C. Arsov, F. Ziayee, J. Morawitz, B. Valentin, K. L. Radke, M. Giessing, I Esposito, P. Albers, G. Antoch, T. Ullrich
Summary: This study evaluated the value of mpMRI in predicting PCA aggressiveness and found significant correlations between MRI parameters and histopathologic grade groups, with the MRI grading groups providing the strongest prediction of biopsy ISUP grade groups.
EUROPEAN RADIOLOGY
(2022)
Article
Oncology
A. Kamoun, G. Cancel-Tassin, G. Fromont, N. Elarouci, L. Armenoult, M. Ayadi, J. Irani, X. Leroy, A. Villers, G. Fournier, L. Doucet, S. Boyault, L. Brureau, L. Multigner, A. Diedhiou, M. Roupret, E. Comperat, P. Blanchet, A. de Reynies, O. Cussenot
ANNALS OF ONCOLOGY
(2018)
Article
Urology & Nephrology
Sophie M. Bruinsma, Liying Zhang, Monique J. Roobol, Chris H. Bangma, Ewout W. Steyerberg, Daan Nieboer, Mieke Van Hemelrijck
Article
Oncology
M. Frasca, P. Soubeyran, C. Bellera, M. Rainfray, K. Leffondre, S. Mathoulin-Pelissier
EUROPEAN JOURNAL OF CANCER
(2018)
Editorial Material
Urology & Nephrology
Arnauld Villers, Jonathan Olivier
Article
Urology & Nephrology
Andrew Vickers, Emily A. Vertosick, Daniel D. Sjoberg, Freddie Hamdy, David Neal, Anders Bjartell, Jonas Hugosson, Jenny L. Donovan, Arnauld Villers, Stephen Zappala, Hans Lilja
JOURNAL OF UROLOGY
(2018)
Article
Urology & Nephrology
D. Robert Siemens, Laurence Klotz, Axel Heidenreich, Simon Chowdhury, Arnauld Villers, Benoit Baron, Steve van Os, Nahla Hasabou, Fong Wang, Ping Lin, Neal D. Shore
JOURNAL OF UROLOGY
(2018)
Article
Medicine, General & Internal
Matthew R. Smith, Fred Saad, Simon Chowdhury, Stephane Oudard, Boris A. Hadaschik, Julie N. Graff, David Olmos, Paul N. Mainwaring, Ji Youl Lee, Hiroji Uemura, Angela Lopez-Gitlitz, Geralyn C. Trudel, Byron M. Espina, Youyi Shu, Youn C. Park, Wayne R. Rackoff, Margaret K. Yu, Eric J. Small
NEW ENGLAND JOURNAL OF MEDICINE
(2018)
Article
Medicine, General & Internal
V Kasivisvanathan, A. S. Rannikko, M. Borghi, V Panebianco, L. A. Mynderse, M. H. Vaarala, A. Briganti, L. Budaus, G. Hellawell, R. G. Hindley, M. J. Roobol, S. Eggener, M. Ghei, A. Villers, F. Bladou, G. M. Villeirs, J. Virdi, S. Boxler, G. Robert, P. B. Singh, W. Venderink, B. A. Hadaschik, A. Ruffion, J. C. Hu, D. Margolis, S. Crouzet, L. Klotz, S. S. Taneja, P. Pinto, I Gill, C. Allen, F. Giganti, A. Freeman, S. Morris, S. Punwani, N. R. Williams, C. Brew-Graves, J. Deeks, Y. Takwoingi, M. Emberton, C. M. Moore
NEW ENGLAND JOURNAL OF MEDICINE
(2018)
Article
Multidisciplinary Sciences
Tytti Turkia, Erkki Korpimaki, Alexandre Villers, Vesa Selonen
Article
Urology & Nephrology
B. Reix, J. -C. Bernhard, J. -J. Patard, P. Bigot, A. Villers, E. Suer, N. S. Vuong, G. Verhoest, Q. Alimi, J. -B. Beauval, T. Benoit, F. -X. Nouhaud, C. Lenormand, N. Hamidi, J. Cai, M. Eto, S. Larre, A. El Bakhri, G. Ploussard, A. Hung, N. Koutlidis, A. Schneider, J. Carrouget, S. Droupy, S. Marchal, A. Doerfler, S. Seddik, T. Matsugasumi, X. Orsoni, A. Descazeaud, C. Pfister, K. Bensalah, M. Soulie, I. Gill, V. Flamand
PROGRES EN UROLOGIE
(2018)
Article
Urology & Nephrology
Kae Jack Tay, Mahul B. Amin, Sangeet Ghai, Rafael E. Jimenez, James G. Kench, Laurence Klotz, Rodolfo Montironi, Satoru Muto, Ardeshir R. Rastinehad, Baris Turkbey, Arnauld Villers, Thomas J. Polascik
WORLD JOURNAL OF UROLOGY
(2019)
Article
Urology & Nephrology
Christopher Warlick, Jurgen Futterer, Mahir Maruf, Arvin K. George, Ardeshir R. Rastinehad, Peter A. Pinto, Ahmed El-Shater Bosaily, Arnauld Villers, Caroline M. Moore, Neil Mendhiratta, Samir S. Taneja, Osamu Ukimura, Badrinath R. Konety
WORLD JOURNAL OF UROLOGY
(2019)
Article
Oncology
Andreas G. Wibmer, Michael W. Kattan, Francesco Alessandrino, Alexander D. J. Baur, Lars Boesen, Felipe Boschini Franco, David Bonekamp, Riccardo Campa, Hannes Cash, Violeta Catala, Sebastien Crouzet, Sounil Dinnoo, James Eastham, Fiona M. Fennessy, Kamyar Ghabili, Markus Hohenfellner, Angelique W. Levi, Xinge Ji, Vibeke Logager, Daniel J. Margolis, Paul C. Moldovan, Valeria Panebianco, Tobias Penzkofer, Philippe Puech, Jan Philipp Radtke, Olivier Rouviere, Heinz-Peter Schlemmer, Preston C. Sprenkle, Clare M. Tempany, Joan C. Vilanova, Jeffrey Weinreb, Hedvig Hricak, Amita Shukla-Dave
Summary: In this study, a nomogram combining MRI findings with other patient data was developed to accurately diagnose extraprostatic tumor growth in patients with newly diagnosed prostate cancer. The nomogram showed significantly greater accuracy compared to clinical benchmark models, providing a valuable tool for physicians in predicting extraprostatic extension of prostate cancer.
Article
Oncology
Harry J. de Koning, Roman Gulati, Sue M. Moss, Jonas Hugosson, Paul F. Pinsky, Christine D. Berg, Anssi Auvinen, Gerald L. Andriole, Monique J. Roobol, E. David Crawford, Vera Nelen, Maciej Kwiatkowski, Marco Zappa, Marcos Lujan, Arnauld Villers, Tiago M. de Carvalho, Eric J. Feuer, Alex Tsodikov, Angela B. Mariotto, Eveline A. M. Heijnsdijk, Ruth Etzioni
Review
Urology & Nephrology
Matteo Manfredi, Fabrizio Mele, Diletta Garrou, Jochen Walz, Jurgen J. Futterer, Filippo Russo, Lorenzo Vassallo, Arnauld Villers, Mark Emberton, Massimo Valerio
MINERVA UROLOGICA E NEFROLOGICA
(2018)