Article
Medicine, General & Internal
Olivier Lopez, Olivier Chevallier, Kevin Guillen, Pierre-Olivier Comby, Julie Pellegrinelli, Claire Tinel, Nicolas Falvo, Marco Midulla, Eric Mourey, Romaric Loffroy
Summary: The study demonstrates that SAE prior to PCA is safe and effective for managing renal malignancies in high-risk patients. Major complications were not recorded, and the majority of patients showed no residual tumor at 6-week imaging follow-up. Decrease in hemoglobin concentration was noted, but only one patient required blood transfusion without further intervention.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Oncology
Yen-Ting Lin, Siu-Wan Hung, Ming-Cheng Liu, Kun-Yuan Chiu, Jyh-Wen Chai, Jin-Ching Lin
Summary: This study investigated the safety and efficacy of percutaneous cryoablation for renal tumors under local anesthesia and pain control. The results showed that cryoablation is a reliable treatment method with a high local recurrence-free survival rate, and the main complication is hemorrhage.
ANTICANCER RESEARCH
(2023)
Article
Oncology
Benjamin Moulin, Tarek Kammoun, Regis Audoual, Stephane Droupy, Vincent Servois, Paul Meria, Jean Paul Beregi, Julien Frandon
Summary: This study investigated the efficacy of single-probe percutaneous cryoablation in managing small renal masses and its impact on recurrence rates. The findings suggest that single-probe cryoablation is a promising modality with cost-effectiveness and ergonomic advantages, but further refinement and research are needed.
Article
Medicine, General & Internal
Lorenzo Bertolotti, Federica Segato, Francesco Pagnini, Sebastiano Buti, Andrea Casarin, Antonio Celia, Francesco Ziglioli, Umberto Maestroni, Giuseppe Pedrazzi, Velio Ascenti, Chiara Martini, Calogero Cicero, Massimo De Filippo
Summary: The efficacy and complication rates of percutaneous radiofrequency ablation (RFA) and cryoablation (CA) in the treatment of T1 renal masses were retrospectively investigated. The results showed that both RFA and CA were effective in treating renal masses, with rare major complications.
Article
Urology & Nephrology
Michele Rizzo, Andrea Piasentin, Giacomo Rebez, Gianluca Giannarini, Paolo Umari, Camilla Sachs, Antonio Celia, Nicola Pavan, Luca Balestrieri, Giorgio Artuso, Michele Bertolotto, Carlo Trombetta, Giovanni Liguori
Summary: This study analyzed mid-term outcomes of CA in treating high-complexity cT1 renal masses, showing that CA provides good preservation of renal function for patients, although there is a higher recurrence rate compared to surgically treated patients.
MINERVA UROLOGY AND NEPHROLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Roberto Luigi Cazzato, Pierre De Marini, Pierre Auloge, Loic Leclerc, Thibault Tricard, Veronique Linder, Marion Jost, Nitin Ramamurthy, Herve Lang, Julien Garnon, Afshin Gangi
Summary: MRI-guided biopsy of solid renal masses shows high diagnostic accuracy and low complication rate, which may be beneficial for inaccessible tumors.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Renato N. Zangiacomo, Guilherme L. P. Martins, Publio C. C. Viana, Natally Horvat, Marco A. Arap, William C. Nahas, Miguel Srougi, Giovanni G. Cerri, Marcos R. Menezes
Summary: The study showed that percutaneous thermoablation is a feasible and effective first-line therapy for healthy surgical candidates with small renal masses (T1a). The 5-year LTPFS, OS, CSS, and MFS rates were 93.0%, 98.4%, 100% and 100%, respectively, with a major complication rate of only 2.3%.
EUROPEAN RADIOLOGY
(2021)
Article
Urology & Nephrology
Paolo Umari, Michele Rizzo, Michele Billia, Fulvio Stacul, Michele Bertolotto, Maria A. Cova, Gianmarco Bondonno, Davide Perri, Giovanni Liguori, Alessandro Volpe, Carlo Trombetta
Summary: This study found that active surveillance (AS) and percutaneous cryoablation (PCA) provide similar survival outcomes for patients with small renal masses, making them safe and valid treatment options for elderly and comorbid patients.
MINERVA UROLOGY AND NEPHROLOGY
(2022)
Article
Medicine, General & Internal
Andrea Piasentin, Francesco Claps, Tommaso Silvestri, Giacomo Rebez, Fabio Traunero, Maria Carmen Mir, Michele Rizzo, Antonio Celia, Calogero Cicero, Martina Urbani, Luca Balestreri, Lisa Pola, Fulvio Lagana, Stefano Cernic, Maria Assunta Cova, Michele Bertolotto, Carlo Trombetta, Giovanni Liguori, Nicola Pavan
Summary: This study assessed the efficacy and safety of percutaneous cryoablation for small renal masses in a large cohort of patients who were not eligible for surgery. The results showed a high success rate of this method in patients who were not suitable for surgery. Tumors with a diameter larger than 25 mm had a higher rate of complications compared to tumors with a diameter less than or equal to 25 mm, but the majority of patients maintained stable renal function.
MEDICINA-LITHUANIA
(2022)
Article
Oncology
Pan Gao, He Cai, Zhong Wu, Bing Peng, Yunqiang Cai
Summary: This study compared the effectiveness of laparoscopic pancreaticoduodenectomy (LPD), open transduodenal ampullectomy (OTDA), and laparoscopic transduodenal ampullectomy (LTDA) in the treatment of pre-malignant tumors of the ampulla of Vater. The results showed that LTDA had shorter operative time, less blood loss, and lower complication rates compared to LPD and OTDA. Therefore, LTDA surgery is safe and feasible for well-selected patients, but multidisciplinary preoperative planning is necessary.
FRONTIERS IN ONCOLOGY
(2023)
Review
Medicine, General & Internal
Lorenzo Bertolotti, Maria Vittoria Bazzocchi, Enrico Iemma, Francesco Pagnini, Francesco Ziglioli, Umberto Maestroni, Annalisa Patera, Matteo Pio Natale, Chiara Martini, Massimo De Filippo
Summary: Over the past two decades, the detection rate of small renal masses has increased, leading to the preference for nephron-sparing treatments. Thermal ablation, including radiofrequency ablation, cryoablation, and microwave ablation, has gained popularity as a minimally invasive alternative with good clinical outcomes and low recurrence rates. These techniques require imaging studies, such as ultrasound and CT, to assess lesions and plan procedures. This review aims to compare different ablative modalities and imaging guides, providing guidance for interventional radiologists in selecting the best treatment option.
Article
Radiology, Nuclear Medicine & Medical Imaging
Roberto Luigi Cazzato, Pierre De Marini, Ian Leonard-Lorant, Loic Leclerc, Pierre Auloge, Thibault Tricard, Danoob Dalili, Julien Garnon, Herve Lang, Afshin Gangi
Summary: This study retrospectively analyzed a 10-year experience of renal tumor cryoablation on a 1.5 T MRI unit, showing acceptable morbidity and high survival estimates. Further studies are needed to evaluate whether the potential reduced incidence of adverse events justifies large-scale implementation of this interventional modality.
INVESTIGATIVE RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yasuhiro Fukushima, Junpei Nakamura, Yuko Seki, Masashi Ando, Masaya Miyazaki, Yoshito Tsushima
Summary: This study aimed to evaluate patients' radiation dose in CT-fluoroscopy-guided cryoablation for small renal tumors and factors affecting it. The results showed that most of the radiation dose (89.8%) was attributed to CT-fluoroscopy, and increasing cryoneedle punctures and combined hydro- and/or pneumodissection procedures led to higher total entrance skin dose.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ahmad Parvinian, John J. Schmitz, Brian T. Welch, Thomas D. Atwell, Jonathan M. Morris, David A. Woodrum, A. Nicholas Kurup
Summary: This study confirmed the feasibility and safety of percutaneous cryoablation for the treatment of lymph node metastases, with a high technical success rate and good long-term local control outcomes. Additional research is needed to evaluate the long-term efficacy of this technique and its role in oncologic care.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2021)
Article
Urology & Nephrology
Jens Steensen Knudsen, Louise Aarup Duus, Theresa Junker, Bo Mussmann, Ole Graumann
Summary: This study retrospectively evaluated renal function after percutaneous cryoablation (PCA) and found minimal decline in renal function 12 months post-operation. PCA is considered a safe and effective treatment method even for patients with reduced renal function.
JOURNAL OF ENDOUROLOGY
(2023)