Review
Dentistry, Oral Surgery & Medicine
Ronald Ordinola-Zapata, W. Craig Noblett, Alejandro Perez-Ron, Zhou Ye, Jorge Vera
Summary: The outcome of root canal treatment is influenced by various factors, including intraoperative factors, host, and microbial factors. It is important for clinicians to analyze these variables and incorporate them into the disinfection strategy to maximize the chances of healing.
INTERNATIONAL ENDODONTIC JOURNAL
(2022)
Article
Health Care Sciences & Services
Shilpa Bhandi, Shankargouda Patil, Nezar Boreak, Hitesh Chohan, Abdulaziz S. AbuMelha, Mazen F. Alkahtany, Khalid H. Almadi, Thilla Sekar Vinothkumar, A. Thirumal Raj, Luca Testarelli
Summary: Different intracanal medicaments have varying effects on the viability and survival of dental pulp stem cells at different doses and exposure times. Calcium hydroxide and triamcinolone promote cell viability, while doxycycline, potassium iodide, and glutaraldehyde increase cell death.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Farzaneh Afkhami, Shahrzad Razavi, Sholeh Ghabraei
Summary: This study evaluated the effect of different commercially used calcium hydroxide and other intracanal medicaments on the dislodgement resistance of mineral trioxide aggregate (MTA) to root canal dentin. The results showed that the duration of application and the type of medicament did not significantly affect the dislodgement resistance of MTA to root dentin, but chlorhexidine exhibited promising effect.
Article
Dentistry, Oral Surgery & Medicine
AlMaha S. AlGazlan, Sayed H. Auda, Hanan Balto, Fahd Alsalleeh
Summary: This study found that combining silver nanoparticles with calcium hydroxide was more effective in inhibiting the biofilm of Fusobacterium nucleatum compared to using either material alone.
JOURNAL OF ENDODONTICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Marcela Carvalho Espaladori, Julia Mourao Braga Diniz, Luciana Carla Neves de Brito, Warley Luciano Fonseca Tavares, Toshihisa Kawai, Leda Quercia Vieira, Antonio Paulino Ribeiro Sobrinho
Summary: The study found that using selenium as a root canal dressing significantly reduced microbial load, and selenium also potentiated the effects of calcium hydroxide, inducing an anti-inflammatory response in periapical tissues.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Sarah Alfadda, Theeb Alquria, Eda Karaismailoglu, Hacer Aksel, Adham A. Azim
Summary: The study showed that calcium hypochlorite (Ca[OCl](2)) had the best disinfection effect on root canals, but it also reduced cell viability and mineralization activity. However, the adverse effects on cells could be neutralized with 10% ascorbic acid.
JOURNAL OF ENDODONTICS
(2021)
Article
Multidisciplinary Sciences
Camila Soares Lopes, Mateus Machado Delfino, Mario Tanomaru-Filho, Estela Sasso-Cerri, Juliane Maria Guerreiro-Tanomaru, Paulo Sergio Cerri
Summary: This study evaluated the biocompatibility and hepatotoxicity of a new bioceramic intracanal medicament, Bio-C Temp. The results showed that Bio-C Temp is biocompatible and does not have hepatotoxic effects.
SCIENTIFIC REPORTS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Firas Elmsmari, Jose Antonio Gonzalez Sanchez, Fernando Duran-Sindreu, Roumaissa Belkadi, Marta Espina, Maria Luisa Garcia, Elena Sanchez-Lopez
Summary: The study successfully developed and characterized calcium hydroxide-loaded PLGA nanoparticles, which showed a stable drug release profile and greater penetration inside dentinal tubules when compared to free calcium hydroxide.
INTERNATIONAL ENDODONTIC JOURNAL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Esther Sook Kuan Kok, Xian Jin Lim, Soo Xiong Chew, Shu Fen Ong, Lok Yin See, Siao Hua Lim, Ling Ang Wong, Fabian Davamani, Venkateshbabu Nagendrababu, Amr Fawzy, Umer Daood
Summary: The study compared the antimicrobial efficacy of k21 with other medicaments against E. faecalis and C. albicans biofilms, showing that 2% k21 had the highest percentage of reduction and can be considered as an alternative intracanal medicament.
Article
Dentistry, Oral Surgery & Medicine
Flavia F. C. Teixeira, Flavia G. R. Cardoso, Nadia S. Ferreira, Ana P. M. Gomes, Bruna J. M. Corazza, Marcia C. Valera, Frederico C. Martinho
Summary: The study found that calcium hydroxide intracanal medications effectively reduced the levels of MMP-1, MMP-2, and MMP-9 in periapical tissues, showing similar effectiveness between Ca(OH)(2) + SSL and Ca(OH)(2) + 2% CHX gel. However, these medications had no significant impact on TIMP-1 and TIMP-2 levels, with positive correlations between MMP-1 and TIMP-1 and MMP-1 and TIMP-2.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Shymaa Shaaban, Salma Genena, Alaaeldin Elraggal, Gamal M. Hamad, Marwa A. Meheissen, Sybel Moussa
Summary: This study evaluated the antibacterial activity of multi-strain probiotics supernatants (MSP) - Lactobacillus plantarum, Lactobacillus rhamnosus, and Lactobacillus acidophilus as an intracanal medication on Enterococcus faecalis (E. faecalis) biofilm in a tooth model. The results showed that MSP has a similar antibacterial effect to calcium hydroxide (Ca(OH)(2)).
Article
Engineering, Biomedical
Meshal Muhammad Naeem, Huma Sarwar, Aliza Nisar, Shahbaz Ahmed, Juzer Shabbir, Zohaib Khurshid, Paulo J. Palma
Summary: The application of intracanal medicaments such as calcium hydroxide and propolis can affect the physical properties of root dentine. This study compared the effects of propolis and calcium hydroxide on the microhardness of root dentine. It was found that propolis increased the microhardness over time, while calcium hydroxide decreased it.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Review
Dentistry, Oral Surgery & Medicine
Maarten A. Meire, Suzette van der Waal
Summary: To ensure predictable decontamination of the root canal system, the use of intracanal medication is sometimes added to the chemo-mechanical preparation. As microbial control is crucial for resolving apical periodontitis, intensive research has been conducted on root canal disinfection strategies. This review examines the experimental models associated with different levels of infection and evaluates their value and methodology.
INTERNATIONAL ENDODONTIC JOURNAL
(2022)
Article
Chemistry, Physical
Junyoung Kim, Tae Ho Kim, Jong Hyeon Lee, Young Ah Park, Yu Jin Kang, Hong Geun Ji
Summary: A porous nanocomposite of layered double hydroxide (LDH) nanosheets and chitosan biopolymer was developed for easy uptake and selective release of cosmetic liposome capsules. The nanocomposite exhibited a high BET surface area and porous structure, allowing for controlled release of large liposome particles depending on solution pH and anions. The polymer network effectively blocked liposome release and the nanocomposites could be successfully reused after washing with ethanol.
APPLIED CLAY SCIENCE
(2021)
Article
Dentistry, Oral Surgery & Medicine
Frederico C. Martinho, Bruna J. M. Corazza, Rayana D. Khoury, Esteban I. F. Orozco, Cassia C. Toia, Felipe P. Machado, Marcia C. Valera
Summary: This study investigated the impact of NAC and Ca(OH)(2) intracanal medications (ICMs) on primary endodontic infection with apical periodontitis (PEIAP). The results showed that NAC was effective in eliminating bacterial species that were resistant to both ICMs.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Anatomy & Morphology
Nidambur Vasudev Ballal, Poornika Gandhi, Namita N. Kashyap
Summary: This study evaluated the influence of infiltrated alkaline biomaterials on the bond strength of composites obtained with different adhesive systems, showing that the universal adhesive system had better resistance to alkaline contamination compared to the etch-and-rinse system.
MICROSCOPY RESEARCH AND TECHNIQUE
(2021)
Article
Dentistry, Oral Surgery & Medicine
N. Ballal, H. F. Duncan, D. B. Wiedemeier, N. Rai, P. Jalan, V Bhat, V. S. Belle, M. Zehnder
Summary: In this study, it was found that the levels of neutrophil gelatinase 9 (MMP-9)/total protein (TP) and NaOCl lavage significantly influenced pulp survival in cariously exposed and directly capped teeth, while mild preoperative discomfort did not have an impact.
JOURNAL OF DENTAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Nidambur Vasudev Ballal, Rajkumar Narkedamalli, Nikita B. Ruparel, Padmaja A. Shenoy, Vinutha R. Bhat, Vijetha Shenoy Belle
Summary: The objective of this study was to analyze the effect of 7% maleic acid root conditioning on the release of TGF-I31 in infected root canals. The results showed that bacterial biofilms modified the release of TGF-I31, and 7% maleic acid exhibited significant efficacy in releasing TGF-I31 growth factor from radicular dentin.
JOURNAL OF ENDODONTICS
(2022)
Article
Chemistry, Multidisciplinary
Nidambur Vasudev Ballal, Sheetal Rao, Nirmala Rao, Arun Urala, Jun-Sang Yoo, Nadin Al-Haj Husain, Mutlu Oezcan
Summary: Results of the study showed a significant difference in hard tissue bridge formation with ProRoot MTA, while RetroMTA performed better in terms of continuity, morphology, and inflammatory reaction. Although RetroMTA healed pulpal tissue faster, it seemed to be more of a reparative process compared to ProRoot MTA.
APPLIED SCIENCES-BASEL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Shanthana Reddy, Lohith Reddy Mandadi, Kundabala Mala, T. N. Abhinav, Aabha Dave, Manuel S. Thomas
Summary: This study aimed to evaluate the clinical performance of nanocomposite restorations bonded using universal adhesive in self-etch mode for non-carious cervical lesions (NCCLs). The results showed no significant difference between the experimental and control groups in all parameters assessed, but a significant decrease in performance concerning marginal staining, marginal adaptation, and surface texture during the evaluation period in the intra-group analysis.
ARCHIVES OF OROFACIAL SCIENCE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Talita Tartari, Brenda Stefhany Wilchenski, Luana Arantes de Souza Lima, Rodrigo Ricci Vivan, Vasudev Ballal, Marco Antonio Hungaro Duarte
Summary: The purpose of this study was to compare the impact of different irrigation protocols on debris extrusion. Single-rooted teeth were distributed into groups based on the irrigation protocols and the amount of debris extruded was measured. The results showed that the subgroup treated with NaOCl + HEDP mixture had a significantly higher amount of extruded debris, and the different agitation methods had no impact on debris extrusion in all groups.
AUSTRALIAN ENDODONTIC JOURNAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Nidambur Vasudev Ballal, Rajkumar Narkedamalli, Poornika Gandhi, Maria Teresa Arias-Moliz, Pilar Baca, Shubhankar Das, Jothi Varghese, Santosh Laxman Gaonkar, Bola Sadashiva Satish Rao, Joshua Frazier, Brian E. Bergeron, Franklin R. Tay
Summary: This study evaluated the capacity of three 2-in-1 root canal irrigating solutions in removing canal wall smear layer, precipi-tation caused by irrigant interaction, antibacterial activity, and cytotoxicity. The results showed that QMix and SmearOFF were effective in removing smear layers and exhibited good antimicrobial activity. However, QMix and Irritrol showed cytotoxicity. The evaluation of smear layer removal capability, antibacterial activity, and cytotoxicity of 2-in-1 root canal irrigants is important for ensuring their safe use during root canal treatment.
JOURNAL OF DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Tarini Mullick, Nidambur Vasudev Ballal
Summary: The purpose of this study was to compare the efficacy of different irrigating solutions in removing the smear layer from root canals. The results showed that 7% maleic acid was more effective than 17% EDTA and 5% glycolic acid in eliminating the smear layer from the apical portion of the root canal. However, there were no statistically significant differences between the three solutions at the coronal and middle thirds of the root canal.
PESQUISA BRASILEIRA EM ODONTOPEDIATRIA E CLINICA INTEGRADA
(2023)
Article
Dentistry, Oral Surgery & Medicine
Lochan Khullar, Nidambur Vasudev Ballal, Tan Firat Eyuboglu, Mutlu Ozcan
Summary: This study found that irradiation significantly decreased the push-out bond strength of Biodentine and MTA to radicular dentin.
JOURNAL OF APPLIED ORAL SCIENCE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Luciano Giardino, Luigi Generali, Paolo Savadori, Mirela Cesar Barros, Leticia Lobo de Melo Simas, Jolanta Pytko-Polonczyk, Wojciech Wilkonski, Vasudev Ballal, Flaviana Bombarda de Andrade
Summary: This study evaluated the cytotoxicity and antibacterial activity of 10% and 1% citric acid solutions in clinical practice. The results showed that citric acid has cytotoxic effects but also exhibits good antimicrobial properties.
Article
Dentistry, Oral Surgery & Medicine
Ramya Shenoy, Violet D'Souza, M. Kundabala, Animesh Jain, Baranya Suprabha
Summary: This study aimed to investigate the impact of an oral health promotion program on early childhood caries (ECC). The results showed that providing pregnant women with fluoride toothpaste, oral health information, and urgent dental care or atraumatic dental treatment had some beneficial effects in preventing tooth decay in children at two years of age.
CONTEMPORARY CLINICAL DENTISTRY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Nidambur Vasudev Ballal, Prateek Jalan, Namith Rai, Nadin Al-Haj Husain, Mutlu Ozcan
Summary: This study compared the restoration effects of alkasite-based resin composite and resin-modified glass ionomer cement on non-carious cervical dental lesions. The results showed that alkasite-based resin composite performed better in terms of retention and anatomic form, while resin-modified glass ionomer cement showed higher discoloration. The study suggests that alkasite-based resin composite can be recommended as an alternative to resin-modified glass ionomer cement.
EUROPEAN JOURNAL OF PROSTHODONTICS AND RESTORATIVE DENTISTRY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Pattath Kunjan Anju, Tina P. Purayil, Kishore Ginjupalli, Nidambur Banal
Summary: This study evaluated and compared the effect of different concentrations of EDTA, HEDP, and MA on the bond strength of NeoMTA Plus to root canal dentin. The results showed that MA and EDTA had the highest bond strength, with the coronal third having the highest bond strength and the apical third having the lowest bond strength.
PESQUISA BRASILEIRA EM ODONTOPEDIATRIA E CLINICA INTEGRADA
(2022)
Article
Dentistry, Oral Surgery & Medicine
M. Roma, Madhura Sen, Kundabala Mala, Nanditha Sujir, Dharnappa Poojary, Neetha J. Shetty, Ramya Shenoy, Sharon Saldanha
Summary: This study critically assessed the unmet oral health needs and oral health-related quality of life among old age home inhabitants in Karnataka, India. Most participants showed unmet oral health needs and lower GOHAI scores, indicating poor oral health-related quality of life.
CLINICAL COSMETIC AND INVESTIGATIONAL DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Vasudev Ballal, Deepika Khandelwal, Prakash Peralam Yegneswaran, Jothi Varghese, Nadin Al-Haj Husain, Mutlu Ozcan
Summary: The study evaluated the antibacterial efficacy of HybenX against E. faecalis biofilm and its efficiency in removing smear layer. HybenX demonstrated good antimicrobial efficacy against E. faecalis and effectively removed the smear layer in the coronal and middle third of the root canal system.
EUROPEAN JOURNAL OF PROSTHODONTICS AND RESTORATIVE DENTISTRY
(2021)
