Article
Pathology
Ebtesam O. Abo El-Mal, Ashraf M. Abu-Seida, Salma H. El Ashry
Summary: The study compared the effects of Hesperidin, Mineral Trioxide Aggregate (MTA)-Angelus, and calcium hydroxide for direct pulp capping. Hesperidin was found to induce mild inflammation and promote good dentine bridge formation, making it a promising material for pulp capping.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Chawan Manaspon, Chavin Jongwannasiri, Sujin Chumprasert, Noppadol Sa-Ard-Iam, Rangsini Mahanonda, Prasit Pavasant, Thantrira Porntaveetus, Thanaphum Osathanon
Summary: The study found that ProRoot(R) MTA and Biodentine(TM) have favorable in vitro biocompatibility and bioactive properties on human dental pulp stem cells, suggesting their superior regenerative potential compared with DyCal(R) and TheraCal(TM).
Review
Chemistry, Physical
Ermin Nie, Jiali Yu, Rui Jiang, Xiangzhen Liu, Xiang Li, Rafiqul Islam, Mohammad Khursheed Alam
Summary: This systematic review evaluated the dentin regeneration efficacy of direct pulp capping biomaterials, concluding that MTA and Biodentine can induce dentin regeneration. The results suggest that MTA and its variants have better efficacy in the DPC procedure for dentin regeneration.
Article
Multidisciplinary Sciences
Amber Ather, Biraj Patel, Jonathan A. L. Gelfond, Nikita B. Ruparel
Summary: Pulpotomy is an effective treatment for permanent teeth with irreversible pulpitis. Symptomatology, root apex development, and type of biomaterial are significant predictors for treatment success. This meta-analysis is the first study to evaluate the clinical outcome of pulpotomy for carious teeth with irreversible pulpitis, identifying the stage of root development and type of biomaterial as predictors for treatment success.
SCIENTIFIC REPORTS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Rafiqul Islam, Md Refat Readul Islam, Toru Tanaka, Mohammad Khursheed Alam, Hany Mohamed Aly Ahmed, Hidehiko Sano
Summary: The aim of direct pulp capping (DPC) is to promote pulp healing and mineralized tissue barrier formation by placing a dental biomaterial directly over the exposed pulp. Successful application of this approach avoids the need for further and more extensive treatment. This review focuses on the DPC procedure, the materials used, and their mechanisms of action to promote pulpal healing.
JAPANESE DENTAL SCIENCE REVIEW
(2023)
Article
Chemistry, Multidisciplinary
Nidambur Vasudev Ballal, Sheetal Rao, Nirmala Rao, Arun Urala, Jun-Sang Yoo, Nadin Al-Haj Husain, Mutlu Oezcan
Summary: Results of the study showed a significant difference in hard tissue bridge formation with ProRoot MTA, while RetroMTA performed better in terms of continuity, morphology, and inflammatory reaction. Although RetroMTA healed pulpal tissue faster, it seemed to be more of a reparative process compared to ProRoot MTA.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Multidisciplinary
Jayanandan Muruganandhan, Govindarajan Sujatha, Saravanan Poorni, Manali Ramakrishnan Srinivasan, Nezar Boreak, Ahmed Al-Kahtani, Mohammed Mashyakhy, Hitesh Chohan, Shilpa Bhandi, A. Thirumal Raj, Alessio Zanza, Luca Testarelli, Shankargouda Patil
Summary: The study compared four pulp-capping agents and found MTA and ERRM to be more effective than other materials in promoting complete dentinal bridge formation and favorable pulpal response. There were no significant differences between MTA and ERRM.
APPLIED SCIENCES-BASEL
(2021)
Review
Dentistry, Oral Surgery & Medicine
Takashi Matsuura, S. M. Ziauddin, Viviane K. S. Kawata-Matsuura, Kouji Sugimoto, Shizuka Yamada, Atsutoshi Yoshimura
Summary: This review evaluates the long-term effectiveness of calcium silicate-based cement and calcium hydroxide for direct pulp capping to human pulp-exposed permanent teeth. The meta-analyses show that there is a significant difference in success rate between CS and CH, with CS being more effective and predictable.
DENTAL MATERIALS JOURNAL
(2021)
Article
Cell Biology
Milos Papic, Suzana Zivanovic, Tamara Vucicevic, Miona Vuletic, Mirjana V. Papic, Nevena Milivojevic, Ana Miric, Marina Miletic Kovacevic, Marko Zivanovic, Milan Stamenkovic, Vladimir Zivkovic, Slobodanka Mitrovic, Vladimir Jakovljevic, Biljana Ljujic, Milica Popovic
Summary: The study aimed to evaluate the dental pulp responses to rhEPO and/or MTA in pulp capping of inflamed dental pulp in vivo. Pulp capping with rhEPO or MTA + rhEPO resulted in lower inflammation and higher mineralization scores compared to untreated control. Capping with rhEPO or MTA + rhEPO resulted in a favorable effect that was similar or even superior to that of MTA.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2023)
Article
Polymer Science
Mijoo Kim, Marc Hayashi, Bo Yu, Thomas K. Lee, Reuben H. Kim, Deuk-Won Jo
Summary: This study evaluated the mechanical, physical, and biological effects of fucoidan combined with conventional MTA for direct pulp capping. Fucoidan was found to reduce setting time, improve cell migration, and enhance osteogenic ability.
Article
Chemistry, Multidisciplinary
Fei Xie, Chuanda Zhu, Lidong Gong, Ningxin Zhu, Qiang Ma, Yuanyuan Yang, Xinrong Zhao, Man Qin, Zhiqiang Lin, Yuanyuan Wang
Summary: Oral diseases are usually caused by inflammation and bacterial infection, which can be treated by targeting excessive intracellular ROS. NanoCr, a metallic nanoparticle, shows broad antibacterial and anti-inflammatory properties, making it a potential therapy for pulpitis.
Article
Materials Science, Biomaterials
Zhengmao Li, Kunke Xie, Shuang Yang, Ting Yu, Yin Xiao, Yinghong Zhou
Summary: Using Zn-doped bioactive glass micro-nano spheres for dental pulp capping can effectively control infection and inflammation, promote tissue regeneration, and facilitate mineralized dentin formation of dental pulp cells. The method demonstrated excellent dentin regenerative properties in rat experiments.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Dentistry, Oral Surgery & Medicine
Mai Mohamed, Ahmed Abdel Rahman Hashem, Maram Farouk Obeid, Ashraf Abu-Seida
Summary: This study compared the pulpal response of Hoffmann's Pulpine mineral (PMIN) and Pulpine NE (PNE) to mineral trioxide aggregate (MTA) when used as pulpotomy materials in immature permanent teeth. The results showed that PMIN is a promising alternative to MTA.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Polymer Science
Soumya Sheela, Fatma Mousa AlGhalban, Khalil Abdelrazek Khalil, Tahar Laoui, Vellore Kannan Gopinath
Summary: This study developed potential dental pulp capping material by coating mineral trioxide aggregate/hydroxyapatite (MTA/HA) on polycaprolactone (PCL) electrospun membranes. The fabricated membranes were characterized and tested for biocompatibility and cell adhesion, spreading, and migration. The results showed that the PCLMTA membrane exhibited better cell adhesion, spreading, and migration.
Article
Chemistry, Multidisciplinary
AlAnoud Almeshari, Rita Khounganian, Wael Mahdi, Fahd Aljarbou, Shilpa Bhandi, Sara Alsubait
Summary: The study evaluated the effects of using iloprost, MTA, and MTA-iloprost as pulp capping materials on pulpal inflammation and tertiary dentin formation in rat molars. Results showed similar pulpal responses in all groups, suggesting that mixing MTA with iloprost might not have significant clinical benefits.
APPLIED SCIENCES-BASEL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Ira Sierwald, Mike T. John, Darius Sagheri, Julia Neuschulz, Elisabeth Schueler, Christian Splieth, Paul-Georg Jost-Brinkmann, Daniel R. Reissmann
CLINICAL ORAL INVESTIGATIONS
(2016)
Article
Dentistry, Oral Surgery & Medicine
Ira Sierwald, Mike T. John, Oliver Schierz, Christian Hirsch, Darius Sagheri, Paul-Georg Jost-Brinkmann, Daniel R. Reissmann
JOURNAL OF OROFACIAL ORTHOPEDICS-FORTSCHRITTE DER KIEFERORTHOPADIE
(2015)
Article
Health Care Sciences & Services
Daniel R. Reissmann, Mike T. John, Darius Sagheri, Ira Sierwald
QUALITY OF LIFE RESEARCH
(2017)
Article
Dentistry, Oral Surgery & Medicine
A. F. Kahatab, Y. B. Ho, D. O'Reilly, C. Tan, J. McTernan, T. Ahmad, A. O'Halloran, D. Sagheri, A. Abdollahi, C. Mac Giolla Phadraig
EUROPEAN JOURNAL OF DENTAL EDUCATION
(2018)
Article
Health Care Sciences & Services
Ghazal Aarabi, Daniel R. Reissmann, Darius Sagheri, Julia Neuschulz, Guido Heydecke, Christopher Kofahl, Ira Sierwald
QUALITY OF LIFE RESEARCH
(2018)
Article
Dentistry, Oral Surgery & Medicine
Till Dammaschke, Kathrin Nykiel, Darius Sagheri, Edgar Schaefer
AUSTRALIAN ENDODONTIC JOURNAL
(2013)
Article
Clinical Neurology
Darius Sagheri, Alfred Wiater, Petra Steffen, Judith A. Owens
BEHAVIORAL SLEEP MEDICINE
(2010)
Article
Dentistry, Oral Surgery & Medicine
Till Dammaschke, Udo Stratmann, Rudolf-Josef Fischer, Darius Sagheri, Edgar Schaefer
CLINICAL ORAL INVESTIGATIONS
(2011)
Review
Dentistry, Oral Surgery & Medicine
D. Faulks, L. Freedman, S. Thompson, D. Sagheri, A. Dougall
EUROPEAN JOURNAL OF DENTAL EDUCATION
(2012)
Article
Dentistry, Oral Surgery & Medicine
Darius Sagheri, Jacinta McLoughlin, June H. Nunn
QUINTESSENCE INTERNATIONAL
(2013)
Article
Dentistry, Oral Surgery & Medicine
Till Dammaschke, Udo Stratmann, Rudolf-Josef Fischer, Darius Sagheri, Edgar Schaefer
QUINTESSENCE INTERNATIONAL
(2010)
Article
Dentistry, Oral Surgery & Medicine
Till Dammaschke, Philipp Wolff, Darius Sagheri, Udo Stratmann, Edgar Schaefer
QUINTESSENCE INTERNATIONAL
(2010)
Article
Dentistry, Oral Surgery & Medicine
Darius Sagheri, Gernot Wassmer, Petra Hahn, Jacinta McLoughlin
INTERNATIONAL DENTAL JOURNAL
(2009)
Article
Dentistry, Oral Surgery & Medicine
D. Sagheri, J. McLoughlin, J. J. Clarkson
COMMUNITY DENTAL HEALTH
(2009)