Mineralocorticoid receptors in the heart: lessons from cell-selective transgenic animals

CCL2-Dependent Macrophage Recruitment Is Critical for Mineralocorticoid Receptor-Mediated Cardiac Fibrosis, Inflammation, and Blood Pressure Responses in Male Mice

(2014) J.Z. Shen et al.   ENDOCRINOLOGY

Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice

(2014) Jérémy Lagrange et al.   FASEB JOURNAL

Endothelial Cell Mineralocorticoid Receptors Regulate Deoxycorticosterone/Salt-Mediated Cardiac Remodeling and Vascular Reactivity But Not Blood Pressure

(2014) Amanda J. Rickard et al.   HYPERTENSION

Spironolactone Decreases DOCA–Salt–Induced Organ Damage by Blocking the Activation of T Helper 17 and the Downregulation of Regulatory T Lymphocytes

(2014) Cristián A. Amador et al.   HYPERTENSION

Aldosterone Promotes Vascular Remodeling by Direct Effects on Smooth Muscle Cell Mineralocorticoid Receptors

(2013) Dafina Pruthi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Immune mechanisms in hypertension and vascular injury

(2013) Ernesto L. Schiffrin   CLINICAL SCIENCE

Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity

(2013) Nicola Schäfer et al.   EUROPEAN HEART JOURNAL

Aldosterone-Specific Activation of Cardiomyocyte Mineralocorticoid Receptor In Vivo

(2013) Smail Messaoudi et al.   HYPERTENSION

Smooth Muscle Cell Mineralocorticoid Receptors Are Mandatory for Aldosterone–Salt to Induce Vascular Stiffness

(2013) Guillaume Galmiche et al.   HYPERTENSION

Displacement of Cortisol From Human Heart by Acute Administration of a Mineralocorticoid Receptor Antagonist

(2013) Javaid Iqbal et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Myeloid Mineralocorticoid Receptor During Experimental Ischemic Stroke: Effects of Model and Sex

(2013) Ryan A. Frieler et al.   Journal of the American Heart Association

Aldosterone Increases Early Atherosclerosis and Promotes Plaque Inflammation Through a Placental Growth Factor‐Dependent Mechanism

(2013) Adam P. McGraw et al.   Journal of the American Heart Association

Macrophage Mineralocorticoid Receptor Signaling Plays a Key Role in Aldosterone-Independent Cardiac Fibrosis

(2012) Laura A. Bienvenu et al.   ENDOCRINOLOGY

Cardiomyocyte Mineralocorticoid Receptors Are Essential for Deoxycorticosterone/Salt-Mediated Inflammation and Cardiac Fibrosis

(2012) Amanda J. Rickard et al.   HYPERTENSION

Neutrophil Gelatinase-Associated Lipocalin Is a Novel Mineralocorticoid Target in the Cardiovascular System

(2012) Celine Latouche et al.   HYPERTENSION

Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells

(2012) Boonrat Chantong et al.   Journal of Neuroinflammation

Mineralocorticoid receptor antagonism inhibits vein graft remodeling in mice

(2012) Afshin Ehsan et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors

(2012) Amy McCurley et al.   NATURE MEDICINE

Role of Endothelial-Mesenchymal Transition (EndoMT) in the Pathogenesis of Fibrotic Disorders

(2011) Sonsoles Piera-Velazquez et al.   AMERICAN JOURNAL OF PATHOLOGY

Coronary endothelial dysfunction after cardiomyocyte-specific mineralocorticoid receptor overexpression

(2011) Julie Favre et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Aldosterone Regulates Vascular Gene Transcription via Oxidative Stress–Dependent and –Independent Pathways

(2011) Brenna G. Newfell et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Deletion of Cardiomyocyte Mineralocorticoid Receptor Ameliorates Adverse Remodeling After Myocardial Infarction

(2011) Daniela Fraccarollo et al.   CIRCULATION

The Emerging Role of Innate Immunity in the Heart and Vascular System

(2011) Douglas L. Mann   CIRCULATION RESEARCH

Ablation of Mineralocorticoid Receptors in Myocytes But Not in Fibroblasts Preserves Cardiac Function

(2011) Achim Lother et al.   HYPERTENSION

GPR30 Expression Is Required for the Mineralocorticoid Receptor–Independent Rapid Vascular Effects of Aldosterone

(2011) Robert Gros et al.   HYPERTENSION

Interactions of the mineralocorticoid receptor – Within and without

(2011) Jun Yang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Colocalization of mineralocorticoid and EGF receptor at the plasma membrane

(2010) Claudia Grossmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Contribution of Mineralocorticoid and Glucocorticoid Receptors to the Chronotropic and Hypertrophic Actions of Aldosterone in Neonatal Rat Ventricular Myocytes

(2010) Michel F. Rossier et al.   ENDOCRINOLOGY

Placental growth factor mediates aldosterone-dependent vascular injury in mice

(2010) Iris Z. Jaffe et al.   JOURNAL OF CLINICAL INVESTIGATION

Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice

(2010) Michael G. Usher et al.   JOURNAL OF CLINICAL INVESTIGATION

Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

(2010) Faiez Zannad et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deletion of Mineralocorticoid Receptors From Macrophages Protects Against Deoxycorticosterone/Salt-Induced Cardiac Fibrosis and Increased Blood Pressure

(2009) Amanda J. Rickard et al.   HYPERTENSION

Aldosterone Promotes Autoimmune Damage by Enhancing Th17-Mediated Immunity

(2009) Andrés A. Herrada et al.   JOURNAL OF IMMUNOLOGY

Corticosteroid receptors, macrophages and cardiovascular disease

(2009) Amanda J Rickard et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation

(2009) Victoria McEneaney et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Functional Mineralocorticoid Receptors in Human Vascular Endothelial Cells Regulate Intercellular Adhesion Molecule-1 Expression and Promote Leukocyte Adhesion

(2008) Massimiliano Caprio et al.   CIRCULATION RESEARCH

The Role of Mineralocorticoid Receptor Expression in Brain Remodeling after Cerebral Ischemia

(2008) Naofumi Oyamada et al.   ENDOCRINOLOGY

Corticosteroids and Redox Potential Modulate Spontaneous Contractions in Isolated Rat Ventricular Cardiomyocytes

(2008) Michel F. Rossier et al.   HYPERTENSION

Immediate Mineralocorticoid Receptor Blockade Improves Myocardial Infarct Healing by Modulation of the Inflammatory Response

(2008) Daniela Fraccarollo et al.   HYPERTENSION

Mineralocorticoid Receptor Antagonism Attenuates Vascular Apoptosis and Injury via Rescuing Protein Kinase B Activation

(2008) Yongzhong Wei et al.   HYPERTENSION

Aldosterone Regulates Rapid Trafficking of Epithelial Sodium Channel Subunits in Renal Cortical Collecting Duct Cells via Protein Kinase D Activation

(2008) Victoria McEneaney et al.   MOLECULAR ENDOCRINOLOGY

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY