Metabolomics in diabetes research

Genetics of Type 1 Diabetes

(2013) J. A. Noble et al.   Cold Spring Harbor Perspectives in Medicine

Bile acid signaling after an oral glucose tolerance test

(2011) Silke Matysik et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Metabolomics and Cardiovascular Biomarker Discovery

(2011) E. P. Rhee et al.   CLINICAL CHEMISTRY

Bile Acid Metabolism and the Pathogenesis of Type 2 Diabetes

(2011) Janne Prawitt et al.   Current Diabetes Reports

Differentiating short- and long-term effects of diet in the obese mouse using 1H-nuclear magnetic resonance metabolomics

(2011) G. E. Duggan et al.   DIABETES OBESITY & METABOLISM

Metabolomics Reveals Attenuation of the SLC6A20 Kidney Transporter in Nonhuman Primate and Mouse Models of Type 2 Diabetes Mellitus

(2011) Andrew D. Patterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose and Insulin Induction of Bile Acid Synthesis

(2011) Tiangang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beyond glucose: metabolic shifts in responses to the effects of the oral glucose tolerance test and the high-fructose diet in rats

(2011) Shuhai Lin et al.   Molecular BioSystems

Time-dependent changes in the plasma amino acid concentration in diabetes mellitus

(2011) Taiga Mochida et al.   MOLECULAR GENETICS AND METABOLISM

An amino acid profile to predict diabetes?

(2011) Claudia Langenberg et al.   NATURE MEDICINE

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

Metabolomics as a tool for cardiac research

(2011) Julian L. Griffin et al.   Nature Reviews Cardiology

Understanding type 1 diabetes through genetics: advances and prospects

(2011) Constantin Polychronakos et al.   NATURE REVIEWS GENETICS

Obesity, insulin resistance and free fatty acids

(2011) Guenther Boden   Current Opinion in Endocrinology Diabetes and Obesity

Genetics of type 2 diabetes: pathophysiologic and clinical relevance

(2010) Christian Herder et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Role of the gut microbiota in defining human health

(2010) Kei E Fujimura et al.   Expert Review of Anti-Infective Therapy

Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism

(2010) Gemma Brufau et al.   HEPATOLOGY

Opening up the "Black Box": Metabolic phenotyping and metabolome-wide association studies in epidemiology

(2010) Magda Bictash et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Metabolomic Analysis of Livers and Serum from High-Fat Diet Induced Obese Mice

(2010) Hyun-Jin Kim et al.   JOURNAL OF PROTEOME RESEARCH

Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits

(2010) Xinjie Zhao et al.   Metabolomics

Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes

(2010) Susan C. Connor et al.   Molecular BioSystems

Early Hepatic Insulin Resistance in Mice: A Metabolomics Analysis

(2010) Lei O. Li et al.   MOLECULAR ENDOCRINOLOGY

Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity

(2010) Stephanie J. Mihalik et al.   Obesity

Quantitative Metabolomics by 1H-NMR and LC-MS/MS Confirms Altered Metabolic Pathways in Diabetes

(2010) Ian R. Lanza et al.   PLoS One

Thirty-One Novel Biomarkers as Predictors for Clinically Incident Diabetes

(2010) Veikko Salomaa et al.   PLoS One

Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting

(2010) Karsten Suhre et al.   PLoS One

1H-nuclear magnetic resonance spectroscopy-based metabolic assessment in a rat model of obesity induced by a high-fat diet

(2009) So-Hyun Kim et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Metabonomics studies of intact hepatic and renal cortical tissues from diabetic db/db mice using high-resolution magic-angle spinning 1H NMR spectroscopy

(2009) Jingjing Xu et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Cross-Platform Comparison of Methods for Quantitative Metabolomics of Primary Metabolism

(2009) Jörg Martin Büscher et al.   ANALYTICAL CHEMISTRY

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Relationships Between Circulating Metabolic Intermediates and Insulin Action in Overweight to Obese, Inactive Men and Women

(2009) K. M. Huffman et al.   DIABETES CARE

Colestilan monotherapy significantly improves glycaemic control and LDL cholesterol levels in patients with type 2 diabetes: a randomized double-blind placebo-controlled study

(2009) K. Kondo et al.   DIABETES OBESITY & METABOLISM

Glucose stimulates cholesterol 7α-hydroxylase gene transcription in human hepatocytes

(2009) Tiangang Li et al.   JOURNAL OF LIPID RESEARCH

Metabolomic analysis of a human oral glucose tolerance test reveals fatty acids as reliable indicators of regulated metabolism

(2009) Peter Spégel et al.   Metabolomics

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Changes of the plasma metabolome during an oral glucose tolerance test: is there more than glucose to look at?

(2008) Xinjie Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for metabonomics: Biomarker discovery for diabetes mellitus

(2008) Xiang Li et al.   ANALYTICA CHIMICA ACTA

Correlative and quantitative 1H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats

(2008) Shucha Zhang et al.   ANALYTICAL BIOCHEMISTRY

mTOR Inhibition by Rapamycin Prevents  -Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes

(2008) M. Fraenkel et al.   DIABETES

Metabolomic profiling of dietary-induced insulin resistance in the high fat-fed C57BL/6J mouse

(2008) J. Shearer et al.   DIABETES OBESITY & METABOLISM

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

(2008) Matej Orešič et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multi-platform investigation of the metabolome in a leptin receptor defective murine model of type 2 diabetes

(2008) Geoffrey T. Gipson et al.   Molecular BioSystems

Genotype Score in Addition to Common Risk Factors for Prediction of Type 2 Diabetes

(2008) James B. Meigs et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes

(2008) Valeriya Lyssenko et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phylometabonomic Patterns of Adaptation to High Fat Diet Feeding in Inbred Mice

(2008) Jane F. Fearnside et al.   PLoS One