Adipokine inflammation and insulin resistance: the role of glucose, lipids and endotoxin

Apelin–APJ induces ICAM-1, VCAM-1 and MCP-1 expression via NF-κB/JNK signal pathway in human umbilical vein endothelial cells

(2012) Ying Lu et al.   AMINO ACIDS

Omentin inhibits TNF-α-induced expression of adhesion molecules in endothelial cells via ERK/NF-κB pathway

(2012) Xia Zhong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetes

(2012) Jun Panee   CYTOKINE

Omentin plays an anti-inflammatory role through inhibition of TNF-α-induced superoxide production in vascular smooth muscle cells

(2012) Kyosuke Kazama et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Drosophila as a model to study the genetic mechanisms of obesity-associated heart dysfunction

(2012) Soda Balla Diop et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Effect of a Low-Fat Versus a Low-Gycemic-Load Diet on Inflammatory Biomarker and Adipokine Concentrations

(2012) Eli Heggen et al.   Metabolic Syndrome and Related Disorders

Loss of toll-like receptor 3 function improves glucose tolerance and reduces liver steatosis in obese mice

(2012) Linda H. Wu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Apelin, a promising target for type 2 diabetes treatment?

(2012) Isabelle Castan-laurell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Omentin as a novel biomarker of metabolic risk factors

(2012) Rei Shibata et al.   Diabetology & Metabolic Syndrome

Leptin in human physiology and pathophysiology

(2011) Christos S. Mantzoros et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

New insights into adipose tissue dysfunction in insulin resistance

(2011) Barbara Mlinar et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Origins of metabolic complications in obesity

(2011) Stefania Carobbio et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Apelin Treatment Increases Complete Fatty Acid Oxidation, Mitochondrial Oxidative Capacity, and Biogenesis in Muscle of Insulin-Resistant Mice

(2011) C. Attane et al.   DIABETES

High Fat Intake Leads to Acute Postprandial Exposure to Circulating Endotoxin in Type 2 Diabetic Subjects

(2011) A. L. Harte et al.   DIABETES CARE

Endotoxemia Is Associated With an Increased Risk of Incident Diabetes

(2011) P. J. Pussinen et al.   DIABETES CARE

Visfatin in overweight/obesity, type 2 diabetes mellitus, insulin resistance, metabolic syndrome and cardiovascular diseases: a meta-analysis and systemic review

(2011) Yu-Hung Chang et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

The Anglo-Scandinavian Cardiac Outcomes Trial: 11-year mortality follow-up of the lipid-lowering arm in the UK

(2011) Peter S. Sever et al.   EUROPEAN HEART JOURNAL

Leptin Activates Human B Cells to Secrete TNF-α, IL-6, and IL-10 via JAK2/STAT3 and p38MAPK/ERK1/2 Signaling Pathway

(2011) Sudhanshu Agrawal et al.   JOURNAL OF CLINICAL IMMUNOLOGY

A Low-Glycemic Load Diet Reduces Serum C-Reactive Protein and Modestly Increases Adiponectin in Overweight and Obese Adults

(2011) Marian L. Neuhouser et al.   JOURNAL OF NUTRITION

Acute and chronic saturated fatty acid treatment as a key instigator of the TLR-mediated inflammatory response in human adipose tissue, in vitro

(2011) Elham M. Youssef-Elabd et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cardiovascular Event Reduction and Adverse Events Among Subjects Attaining Low-Density Lipoprotein Cholesterol

(2011) Judith Hsia et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Immunity as a link between obesity and insulin resistance

(2011) Nishan S. Kalupahana et al.   MOLECULAR ASPECTS OF MEDICINE

Visfatin Is Regulated by Rosiglitazone in Type 2 Diabetes Mellitus and Influenced by NFκB and JNK in Human Abdominal Subcutaneous Adipocytes

(2011) Kirsty C. McGee et al.   PLoS One

Inflammatory signaling in skeletal muscle insulin resistance: green signal for nutritional intervention?

(2010) Pascal PH Hommelberg et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Identification of Nesfatin-1 in Human and Murine Adipose Tissue: A Novel Depot-Specific Adipokine with Increased Levels in Obesity

(2010) Manjunath Ramanjaneya et al.   ENDOCRINOLOGY

Chemerin Exacerbates Glucose Intolerance in Mouse Models of Obesity and Diabetes

(2010) Matthew C. Ernst et al.   ENDOCRINOLOGY

Apelin Decreases Lipolysis via Gq, Gi, and AMPK-Dependent Mechanisms

(2010) Patrick Yue et al.   ENDOCRINOLOGY

Gluteofemoral body fat as a determinant of metabolic health

(2010) K N Manolopoulos et al.   INTERNATIONAL JOURNAL OF OBESITY

TNF-α Antagonism with Etanercept Decreases Glucose and Increases the Proportion of High Molecular Weight Adiponectin in Obese Subjects with Features of the Metabolic Syndrome

(2010) Takara L. Stanley et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Chemerin Contributes to Inflammation by Promoting Macrophage Adhesion to VCAM-1 and Fibronectin through Clustering of VLA-4 and VLA-5

(2010) R. Hart et al.   JOURNAL OF IMMUNOLOGY

Elevated endotoxin levels in non-alcoholic fatty liver disease

(2010) Alison L Harte et al.   Journal of Inflammation-London

Release of Inflammatory Mediators by Human Adipose Tissue Is Enhanced in Obesity and Primarily by the Nonfat Cells: A Review

(2010) John N. Fain   MEDIATORS OF INFLAMMATION

Body-Mass Index and Mortality among 1.46 Million White Adults

(2010) Amy Berrington de Gonzalez et al.   NEW ENGLAND JOURNAL OF MEDICINE

RANTES release by human adipose tissue in vivo and evidence for depot-specific differences

(2009) Rana Madani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Regulation of carboxylesterase 1 (CES1) in human adipose tissue

(2009) Margareta Jernås et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Drosophila as a lipotoxicity model organism — more than a promise?

(2009) Ronald P. Kühnlein   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Changes in endotoxin levels in T2DM subjects on anti-diabetic therapies

(2009) Omar S Al-Attas et al.   Cardiovascular Diabetology

Systemic chemerin is related to inflammation rather than obesity in type 2 diabetes

(2009) Johanna Weigert et al.   CLINICAL ENDOCRINOLOGY

Low Plasma Apelin in Newly Diagnosed Type 2 Diabetes in Chinese People

(2009) Y. Zhang et al.   DIABETES CARE

Chemerin is associated with markers of inflammation and components of the metabolic syndrome but does not predict coronary atherosclerosis

(2009) Michael Lehrke et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The major inflammatory mediator interleukin-6 and obesity

(2009) Katalin Eder et al.   INFLAMMATION RESEARCH

Tenomodulin Is Highly Expressed in Adipose Tissue, Increased in Obesity, and Down-Regulated during Diet-Induced Weight Loss

(2009) Atsuhito Saiki et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies

(2009) Prospective Studies Collaboration   LANCET

Acute hyperinsulinemia raises plasma interleukin-6 in both nondiabetic and type 2 diabetes mellitus subjects, and this effect is inversely associated with body mass index

(2009) Toralph Ruge et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of diet-induced weight loss on plasma apelin and cytokine levels in individuals with the metabolic syndrome

(2009) M.V. Heinonen et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Apelin Levels Are Increased in Morbidly Obese Subjects with Type 2 Diabetes Mellitus

(2009) Federico Soriguer et al.   OBESITY SURGERY

Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer

(2009) L. A. J. O'Neill et al.   PHARMACOLOGICAL REVIEWS

Fasting plasma levels of nesfatin-1 in patients with type 1 and type 2 diabetes mellitus and the nutrient-related fluctuation of nesfatin-1 level in normal humans

(2009) Qing-Chun Li et al.   REGULATORY PEPTIDES

Waist Circumference and Mortality

(2008) A. Koster et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Ethnic and sex differences in circulating endotoxin levels: A novel marker of atherosclerotic and cardiovascular risk in a British multi-ethnic population

(2008) Michelle A. Miller et al.   ATHEROSCLEROSIS

Apelin Stimulates Glucose Utilization in Normal and Obese Insulin-Resistant Mice

(2008) Cédric Dray et al.   Cell Metabolism

Ghrelin and the differential regulation of des-acyl (DSG) and oct-anoyl ghrelin (OTG) in human adipose tissue (AT)

(2008) K. Kos et al.   CLINICAL ENDOCRINOLOGY

Muscle-Specific IRS-1 Ser->Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle

(2008) K. Morino et al.   DIABETES

High Glucose Induces Toll-Like Receptor Expression in Human Monocytes: Mechanism of Activation

(2008) M. R. Dasu et al.   DIABETES

Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects

(2008) S. M. Reyna et al.   DIABETES

Acute Modulation of Toll-Like Receptors by Insulin

(2008) H. Ghanim et al.   DIABETES CARE

Downregulation of genes involved in NFκB activation in peripheral blood mononuclear cells after weight loss is associated with the improvement of insulin sensitivity in individuals with the metabolic syndrome: the GENOBIN study

(2008) V. D. F. de Mello et al.   DIABETOLOGIA

Effect of hypocaloric diet-induced weight loss in obese women on plasma apelin and adipose tissue expression of apelin and APJ.

(2008) Isabelle Castan-Laurell et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Low Plasma Apelin Levels in Newly Diagnosed Type 2 Diabetes Mellitus

(2008) G. Erdem et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Effects of a high-fat, low- versus high-glycemic index diet: retardation of insulin resistance involves adipose tissue modulation

(2008) Evert M. van Schothorst et al.   FASEB JOURNAL

Effect of the orlistat on serum endotoxin lipopolysaccharide and adipocytokines in South Asian individuals with impaired glucose tolerance

(2008) A. N. Dixon et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Associations of Adiponectin, Resistin, and Tumor Necrosis Factor-α with Insulin Resistance

(2008) Marie-France Hivert et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Epicardial Adipose Tissue as a Source of Nuclear Factor-κB and c-Jun N-Terminal Kinase Mediated Inflammation in Patients with Coronary Artery Disease

(2008) A. R. Baker et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

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(2008) Herbert Tilg et al.   MOLECULAR MEDICINE

General and Abdominal Adiposity and Risk of Death in Europe

(2008) T. Pischon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Apelin, a Novel Adipocytokine, in Relation to Endothelial Function and Inflammation in Kidney Allograft Recipients

(2008) J. Malyszko et al.   TRANSPLANTATION PROCEEDINGS