Article
Medicine, General & Internal
Francesca Battista, Daniel Neunhaeuserer, Anna Centanini, Andrea Gasperetti, Giulia Quinto, Marco Vecchiato, Elia Bianchi, Anna Chiara Frigo, Silvia Bettini, Roberto Vettor, Luca Busetto, Andrea Ermolao
Summary: Cardiorespiratory fitness (CRF) is significantly related to morbidity and mortality in patients with obesity. This study shows that age and BMI are independent determinants of CRF in obese patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Critical Care Medicine
Maria Tholen, Sven-Erik Ricksten, Lukas Lannemyr
Summary: The study demonstrates that levosimendan can increase renal blood flow and improve renal function in patients with AKI after cardiac surgery by dilating renal blood vessels. Compared to the placebo group, the levosimendan group showed a significant increase in renal blood flow, a significant decrease in renal vascular resistance, and a significant increase in the need for norepinephrine dosage.
Article
Health Care Sciences & Services
Xiaowei Ye, Mengjia Sun, Shiyong Yu, Jie Yang, Zhen Liu, Hailin Lv, Boji Wu, Jingyu He, Xuhong Wang, Lan Huang
Summary: Cardiorespiratory fitness is important for coping with high-altitude hypoxic stress, but its association with AMS has not been evaluated. Wearable technology devices, such as smartwatches, can provide a feasible assessment of cardiorespiratory fitness, particularly VO2max, and may contribute to AMS prediction.
JMIR MHEALTH AND UHEALTH
(2023)
Article
Medicine, General & Internal
Camila R. A. de Assumpcao, Danilo M. L. do Prado, Camila P. Jordao, Luciana O. C. Dourado, Marcelo L. C. Vieira, Carla G. de S. P. Montenegro, Carlos E. Negrao, Luis H. W. Gowdak, Luciana D. N. J. De Matos
Summary: The study aims to assess cardiorespiratory capacity in patients with refractory angina using oxygen consumption efficiency slope (OUES) and to investigate the association between ischemic changes and contractile modifications. The results show that patients with refractory angina have low cardiorespiratory capacity, and there is a significant relationship between flattening of O2 pulse response during CPET and contractile alterations detected by exercise stress echocardiography.
Article
Cardiac & Cardiovascular Systems
Vojtech Illinger, Ondeej Materna, Krystof Slaby, Denisa Jicinska, Jan Kovanda, Karel Koubsky, Jan Pokorny, Michal Prochazka, Petra Antonova, Antonin Hoskovec, Jiri Radvansky, Vaclav Chaloupecky, Jan Janousek
Summary: Patients undergoing the Fontan palliation procedure experience significantly reduced exercise capacity, with an age-related decline similar to the general population and negatively correlated with body mass index trends. The provided (V)over dot)O(2)peak reference dataset can assist clinicians in grading the severity of exercise capacity impairment in individual TCPC patients.
Review
Medicine, General & Internal
Arianne Clare Agdamag, Erik H. H. Van Iterson, W. H. Wilson Tang, J. Emanuel Finet
Summary: Heart failure is a complex syndrome with diverse presentations and severity. Current prognostic markers, such as left ventricular ejection fraction, have limitations in accurately predicting outcomes and guiding management decisions. Metabolic exercise testing, which evaluates multisystem responses and aerobic capacity during exercise, provides a more comprehensive and reliable assessment, especially in heart failure patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Helen Triantafyllidi, Dimitrios Benas, Dionyssia Birba, Paraskevi Trivilou, Efstathios Iliodromitis
Summary: The study provided normative reference values for aerobic capacity in apparently healthy Greek subjects for the first time using CPET with a cycle ergometer. Male subjects achieved significantly higher levels of VO2max compared to females across all ages, and a decline in VO2max was observed in older participants of both sexes. Greek subjects had lower AC than North Europe cohort and were almost similar to the USA cohort, emphasizing the need for individual countries to develop their own AC reference values.
HELLENIC JOURNAL OF CARDIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Tomoaki Aoki, Vanessa Wong, Yusuke Endo, Kei Hayashida, Ryosuke Takegawa, Muhammad Shoaib, Santiago J. Miyara, Rishabh C. Choudhary, Tai Yin, Kota Saeki, Simon C. Robson, Lance B. Becker, Koichiro Shinozaki
Summary: Insufficient oxygen supplementation during resuscitation may prolong ischemia and lead to unfavorable biological responses 2 hours after cardiac arrest.
Article
Health Care Sciences & Services
Ori Hochwald, Lea Bentur, Yara Haddad, Moneera Hanna, Merav Zucker-Toledano, Gur Mainzer, Julie Haddad, Michal Gur, Liron Borenstein-Levin, Amir Kugelman, Ronen Bar-Yoseph
Summary: This study found that exercise capacity is lower in late preterm children compared to term children, but within the normal range, and comparable to that of early preterm children, with and without bronchopulmonary dysplasia (BPD). Lung function is only lower than normal in early preterm children.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Geriatrics & Gerontology
Eunhye Chung, Su-Hyun Lee, Hwang-Jae Lee, Yun-Hee Kim
Summary: This study subdivided older adults into two age groups and found that individuals aged 75-84 had worse gait function compared to those aged 65-74. Gait characteristics change with age and these variations increase the risk of falls among older adults. Therefore, customized interventions such as gait training methods may be necessary to prevent age-related falls.
Article
Surgery
Diego Iglesias, Walter Masson, Leandro Barbagelata, Emiliano Rossi, Mishel Mora, Guillermo Cornejo, Juan Lagoria, Cesar Belziti, Norberto Vulcano, Ricardo Marenchino, Rodolfo Pizarro, Hector Ventura
Summary: Cardiopulmonary exercise testing can predict the risk of hospitalizations and mortality in heart transplant recipients, with peak VO2, oxygen pulse, and predicted VO2 independently associated with hospitalization risk at follow up.
CLINICAL TRANSPLANTATION
(2021)
Article
Oncology
Daniel Triguero-Canovas, Francisco Lopez-Rodriguez-Arias, Manuel Gomez-Martinez, Luis Sanchez-Guillen, Franc Peris-Castello, Maria Jose Alcaide-Quiros, Pedro Morillas-Blasco, Antonio Arroyo, Jose Manuel Ramirez
Summary: This study evaluates the impact of home-based prehabilitation on the physical condition of patients treated surgically for colorectal cancer. The results show that home prehabilitation reduces postoperative complications and hospital stay, while significantly improving the 6-minute walk test (6MWT) and cardiopulmonary exercise testing (CPET). There is also a strong correlation between CPET and 6MWT, validating the latter as a useful measure of functional exercise capacity in colorectal patients.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Pediatrics
Sheng-Hui Tuan, Jin-Hui Chung, Guan-Bo Chen, Shu-Fen Sun, I-Hsiu Liou, Chien-Hui Li, Yi-Ju Tsai
Summary: The study compared the exercise capacity as indicated by peak VO2 Z-score during CPET between KD-CA patients with different CA Z-scores. The results showed that KD-CA patients had slightly reduced exercise capacity compared to healthy peers, and KD-CA patients with CA Z-score >= 2.5 had significantly lower peak exercise capacity than those with CA Z-score <2.5. Max-Z could potentially serve as a useful follow-up indicator after the acute stage of KD.
ITALIAN JOURNAL OF PEDIATRICS
(2023)
Article
Biochemistry & Molecular Biology
Shiyi Zeng, Qingzhi Ma, Shenchong Zhang, Conghao Shen, Jing Li, Huifang Zhao, Daliang Guo, Yan Zhang, Hui Yang
Summary: A characteristic Lignin-first strategy was developed through comprehensive investigation of the oxy-organosolv delignification processes under mild conditions. The results showed that the lignin yield could reach about 50% under the optimized process conditions. The use of oxygen induced significant lignin dissolution without affecting the carbohydrate component and lignin structure, resulting in uniform lignin degradation. Additionally, the employment of oxygen extended the lignin removal stage and increased the delignification rate compared to conventional methods.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Sport Sciences
James E. Peterman, Matthew P. Harber, Mary T. Imboden, Mitchell H. Whaley, Bradley S. Fleenor, Jonathan Myers, Ross Arena, Leonard A. Kaminsky
Summary: This study compared the accuracy of exercise-based prediction equations with directly measured CRF and found significant associations between the two, although the equations had a low degree of accuracy in categorizing participants into fitness tertiles. The results suggest the need to include cardiopulmonary measures with maximal exercise to accurately assess CRF within a clinical setting.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2021)
Article
Sport Sciences
Humberto Miranda, Joao Antonio A. A. De Souza, Estevao Scudese, Gabriel A. Paz, Veronica P. Salerno, Patricia Dos Santos Vigario, Jeffrey M. Willardson
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2020)
Review
Orthopedics
Julia Ribeiro Lemos, Felipe Amorim da Cunha, Agnaldo Jose Lopes, Fernando Silva Guimaraes, Fabricio Vieira do Amaral Vasconcellos, Patricia dos Santos Vigario
JOURNAL OF BACK AND MUSCULOSKELETAL REHABILITATION
(2020)
Article
Endocrinology & Metabolism
Nathalie Silva de Morais, Debora Ayres Saraiva, Carolina Corcino, Tatiana Berbara, Annie Schtscherbyna, Karina Moreira, Mario Vaisman, Erik K. Alexander, Patricia Teixeira
Article
Endocrinology & Metabolism
Tatiana Martins Benvenuto Louro Berbara, Nathalie Silva de Morais, Debora Ayres Saraiva, Carolina Martins Corcino, Annie Schtscherbyna, Karina Lucia Moreira, Patricia de Fatima dos Santos Teixeira, Mario Vaisman
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2020)
Article
Endocrinology & Metabolism
Aline Machado Larcher de Almeida, Ricardo Luiz Costantin Delfim, Ana Paula Aguiar Vidal, Maria Clara d'Araujo Couto Martins Chaves, Ana Carolina Lopes Santiago, Marcos Feijo Gianotti, Manuel Domingos da Cruz Goncalves, Mario Vaisman, Denise Pires de Carvalho, Patricia de Fatima dos Santos Teixeira
Summary: The study evaluated the cancer risk of indeterminate thyroid nodules by considering both cytological subcategories and the American Thyroid Association (ATA)-based US risk classification. The highest RoM was related to nuclear atypia (NA) and both architectural and nuclear atypia (ANA) subcategories, while architectural atypia (AA) and oncocytic pattern (OP) had lower RoM. NA and ANA were independently associated with cancer, as were high and intermediate-risk US categories according to ATA. The presence of NA or ANA combined with intermediate US patterns had high RoM values, and combining cytological features with high-risk US categories resulted in RoM exceeding 70%.
Article
Endocrinology & Metabolism
Jose Miguel Dora, Rosa Paula Mello Biscolla, Gustavo Caldas, Janete Cerutti, Hans Graf, Ana O. Hoff, Glaucia M. F. S. Mazeto, Patricia Kunzle Ribeiro Magalhaes, Cleo Otaviano Mesa Junior, Rafael Selbach Scheffel, Patricia de Fatima dos Santos Teixeira, Fernanda Vaisman, Danilo Villagelin, Ana Luiza Maia
Summary: The study aims to develop evidence-based recommendations for thyroid conditions through the Choosing Wisely (CW) initiative. After extensive discussions and voting, 5 final thyroid CW recommendations were determined. These recommendations are designed to avoid unnecessary medical tests, treatments, or procedures, promoting shared decision-making between physicians and patients.
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2021)
Article
Endocrinology & Metabolism
Joao Roberto M. Martins, Danilo G. P. Villagelin, Gisah A. Carvalho, Fernanda Vaisman, Patricia F. S. Teixeira, Rafael S. Scheffel, Jose A. Sgarbi
Summary: During the COVID-19 pandemic, management of thyroid disorders should follow usual practice with caution on over-testing. Newly diagnosed hyperthyroidism should be treated with antithyroid drugs, but rare side effects like agranulocytosis should be monitored for immediate intervention.
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2021)
Article
Endocrinology & Metabolism
Nathalie Silva de Morais, Trevor E. Angell, Sara Ahmadi, Erik K. Alexander, Patricia de Fatima dos Santos Teixeira, Ellen Marqusee
Summary: TSI and TBII assays showed similar performance in differentiating GD from other causes of thyrotoxicosis. In combination, both tests showed little benefit compared with the TBII assay alone. Thyrotropin receptor antibody assay results should be carefully interpreted in patients with mild GD or longstanding disease.
ENDOCRINE PRACTICE
(2022)
Article
Endocrinology & Metabolism
Marina Gabriela Birck, Bianca de Almeida-Pititto, Carolina C. P. S. Janovsky, Alessandra Carvalho Goulart, Itamar S. Santos, Patricia de Fatima dos Santos Teixeira, Jose A. Sgarbi, Sandhi M. Barreto, Bruce B. Duncan, Maria Ines Schmidt, Paulo A. Lotufo, Isabela M. Bensenor
Summary: This study investigated the relationship between thyroid function and the risk of developing diabetes. The results suggest that fT4 and fT3 levels, as well as their conversion ratio, may be associated with incident diabetes, especially in the presence of overweight or obesity. However, further studies are needed to confirm these findings.
Article
Endocrinology & Metabolism
Ricardo Luiz Costantin Delfim, Lia Roque Assumpcao, Flavia Paiva Proenca Lobo Lopes, Patricia de Fatima dos Santos Teixeira
Summary: The study aimed to determine if classifying hypoechogenicity into three degrees could improve the distinction between benign and malignant nodules and influence the Thyroid Imaging Reporting and Data System (TI-RADS) Category 4. A total of 2,574 nodules were retrospectively assessed, and a subanalysis was performed on solid nodules to evaluate mainly TI-RADS 4 nodules. The results showed that mild hypoechogenicity had a lower association with malignancy compared to moderate and marked hypoechogenicity, and there was no significant association between mildly hypoechoic solid nodules and cancer.
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2023)
Article
Geriatrics & Gerontology
Aline S. da S. Correia, Michele L. F. Nascimento, Leticia B. B. de M. Teixeira, Silvana O. E. Silva, Mario Vaisman, Patricia F. S. Teixeira
Summary: The study showed that in older patients, for each 0.1 ng/dL increase in FT4 levels, the risks of functional decline increased by 14.1% and 7.7% for baseline and mean FT4 follow-up levels, respectively. Patients with baseline FT4 levels in the fourth and fifth quintiles had a nearly 9 times higher risk of functional decline compared to those in the first quintile. No association was found between TSH and the outcome.
EUROPEAN GERIATRIC MEDICINE
(2022)
Review
Endocrinology & Metabolism
Patricia de Fatima dos Santos Teixeira, Patricia Borges dos Santos, Carmen Cabanelas Pazos-Moura
THERAPEUTIC ADVANCES IN ENDOCRINOLOGY AND METABOLISM
(2020)
Article
Integrative & Complementary Medicine
Timothy Sam-Kit Tin, Chi-Hsiu Daniel Weng, Patricia dos Santos Vigario, Arthur de Sa Ferreira
JOURNAL OF ACUPUNCTURE AND MERIDIAN STUDIES
(2020)
Article
Medicine, General & Internal
Natalia Treistman, Aline Barbosa Moraes, Stephanie Cozzolino, Patricia de Fatima dos Santos Teixeira, Leonardo Vieira Neto
CASE REPORTS IN MEDICINE
(2019)
Article
Rehabilitation
Raphael C. M. Pereira, Patricia S. Vigario, Miriam R. M. Mainenti, Dalila T. R. Silva, Tatiana R. L. Lima, Thiago Lemos
JOURNAL OF BODYWORK AND MOVEMENT THERAPIES
(2019)