Article
Clinical Neurology
Lu Dong, Elizabeth J. D'Amico, Daniel L. Dickerson, Ryan A. Brown, Alina I. Palimaru, Carrie L. Johnson, Wendy M. Troxel
Summary: Food insecurity is significantly associated with sleep and cardiometabolic health among urban AI/AN youth. Measures should be taken to reduce food insecurity and increase access to healthy foods, as well as implementing sleep interventions for these youth.
Article
Geriatrics & Gerontology
R. Turner Goins, Blythe Winchester, Luohua Jiang, Laura Grau, Maggie Reid, Maria M. Corrada, Spero M. Manson, Joan O'Connell
Summary: The study found that diabetes and cardiovascular disease were associated with increased odds of all-cause dementia among older AI/AN individuals, while hypertension was not. Cerebrovascular disease had the strongest association with all-cause dementia.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Public, Environmental & Occupational Health
Amanda K. Walch, Kathryn A. Ohle, Kathryn R. Koller, Lucinda Alexie, Flora Sapp, Timothy K. Thomas, Andrea Bersamin
Summary: The project aimed to gather the wisdom of local Yup'ik and Cup'ik Elders in the Yukon-Kuskokwim region of Alaska on maintaining a healthy diet and active lifestyle, emphasizing the importance of traditional foods, concerns about changing dietary patterns, and a desire to pass down traditional subsistence practices to younger generations. The perspectives provided a better understanding of local views on how to maintain a healthy diet, physical activities, and traditional values in the face of high obesity risk among Alaska Native children.
Article
Pediatrics
Shaquita Bell, Jason F. Deen, Molly Fuentes, Kelly Moore
Summary: American Indian and Alaska Native populations face significant health disparities, especially starting from childhood. Health care providers specializing in pediatrics have the unique opportunity to address disease rates among AI/AN youth and improve their overall health status through advocacy and policy making.
Article
Cardiac & Cardiovascular Systems
Sarah H. Nash, Gretchen Day, Vanessa Y. Hiratsuka, Julie Beans, Diana Redwood, Peter Holck, Barbara Howard, Jason Umans, Kathryn R. Koller
Summary: The study found that weight gain over a 10-year period was not significantly associated with changes in cardiometabolic markers among Alaska Native men, but was associated with a decrease in high-density lipoprotein cholesterol among women.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Review
Medicine, General & Internal
Dian W. Damaiyanti, Zong-Yun Tsai, Ainun Nizar Masbuchin, Ching-Ying Huang, Ping -Yen Liu
Summary: Diabetes, dyslipidemia, obesity, and cardiac dysfunction are associated with oxidative stress and contribute to cardiovascular diseases. Obesity can cause increased white fat, nonalcoholic fatty liver disease, diabetes, and cardiovascular disease. The root causes of cardiovascular diseases associated with diabetes are high glucose levels, abnormal lipids, and metabolic syndrome.
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
(2023)
Article
Immunology
Ian D. Plumb, Prabhu P. Gounder, Leisha D. Nolen, Stephanie C. Massay, Louisa Castrodale, Joseph McLaughlin, Mary Snowball, Chriss Homan, Noele P. Nelson, Rosalyn Singleton, Michael G. Bruce, Brian J. McMahon
Summary: After assessing the impact of hepatitis A vaccine in Alaska Native persons, it was found that only 6 cases of hepatitis A were identified from 1996 to 2018, all in unvaccinated adults. The study highlights the importance of achieving sufficient vaccination coverage over time to protect populations against hepatitis A.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Nutrition & Dietetics
Bert B. Boyer, Scarlett E. Hopkins, Howard W. Wiener, Jonathan Q. Purnell, Diane M. O'Brien, Cindy X. Zhang, Joseph E. Aslan, Theresa Aliwarga, Jeremy J. Pomeroy, Kenneth E. Thummel, Hemant K. Tiwari
Summary: This study found that habitual intake of marine mammals and fish rich in n-3 PUFAs is associated with reduced systemic inflammation in Yup'ik Alaska Native adults.
JOURNAL OF NUTRITION
(2022)
Article
Public, Environmental & Occupational Health
Cassandra J. Nikolaus, Ka'imi Sinclair, Dedra Buchwald, Astrid M. Suchy-Dicey
Summary: Evidence suggests that perceived stress and psychological resilience are related to cardiometabolic disease among American Indian and Alaska Native populations, with obesity being the most common health indicator reported. However, further research is needed to confirm these relationships and explore potential mediators. This study surveyed 496 AI/AN adults and found associations between perceived stress and self-reported prediabetes and diabetes, but found no mediating effect of psychological resilience.
PREVENTIVE MEDICINE REPORTS
(2021)
Review
Endocrinology & Metabolism
Nami Mohammadian Khonsari, Patricia Khashayar, Ehsan Shahrestanaki, Roya Kelishadi, Sahar Mohammadpoor Nami, Motahar Heidari-Beni, Zahra Esmaeili Abdar, Ozra Tabatabaei-Malazy, Mostafa Qorbani
Summary: This systematic review and meta-analysis showed that normal weight obesity (NWO) increased the odds of cardiometabolic risk factors (CMRFs). These findings indicate the inadequacy of BMI measurement and emphasize the need for body fat assessment for a better obesity risk assessment.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Harsh Bahrar, Siroon Bekkering, Rinke Stienstra, Mihai G. Netea, Niels P. Riksen
Summary: Low-grade systemic inflammation is an important component of atherosclerotic cardiovascular disease, and long-term activation of myeloid cells plays a crucial role in this process. Obesity and metabolic complications induce long-lasting inflammatory reprogramming of innate immune cells, leading to atherosclerosis. This review discusses the mechanisms through which innate immune cells undergo long-term changes upon exposure to endogenous ligands, termed "trained immunity". Inappropriate induction of trained immunity contributes to hyperinflammation and proatherogenic changes, highlighting the importance of identifying novel pharmacological targets for preventing or treating cardiovascular diseases.
CARDIOVASCULAR RESEARCH
(2023)
Article
Ecology
Wendy F. Smythe, Sarah Peele
Summary: Understanding when Native students discover ecology and addressing factors contributing to low enrollment of diverse students, particularly Native students, in field sciences like ecology, are essential for diversifying science disciplines and increasing representation of underrepresented groups in the workforce.
ECOLOGICAL APPLICATIONS
(2021)
Article
Obstetrics & Gynecology
Kelly R. Moore, Sarah Stotz, Hiba Abujaradeh, Gale Marshall, Martha A. Terry, Denise Charron-Prochownik
Summary: Recommendations from the 12 participants included: (1) the best ways to communicate with AI/AN teenagers, (2) the importance of parental, family, and community education and engagement to support AI/AN teenagers in GDM risk reduction, and (3) building on traditional AI/AN cultural values and practices, while accommodating differences between tribes and regions.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2021)
Review
Immunology
Eric Toussirot, Irene Gallais-Serezal, Francois Aubin
Summary: Psoriasis and psoriatic arthritis are immune-mediated diseases that affect the skin, joints or both. They involve complex pathophysiological mechanisms and increased inflammation. These conditions are also associated with a higher risk of cardiometabolic diseases, which are linked to systemic inflammation and can impact disease severity and treatment outcomes.
FRONTIERS IN IMMUNOLOGY
(2022)
Editorial Material
Medicine, General & Internal
Thomas D. Sequist
Summary: This viewpoint reviews the evidence of poor health outcomes experienced by American Indian/Alaska Native persons due to structural disadvantage, and proposes an aggressive agenda to improve their health and well-being by addressing social determinants of health, improving access to and quality of care, and improving data availability and transparency.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)