Article
Clinical Neurology
Kannapas Kittayarak, Pichai Ittasakul
Summary: The practice of electroconvulsive therapy (ECT) in Thailand has seen significant development over the past two decades, with the majority of patients now being treated with modified ECT. The use of pre-treatment investigations, devices providing brief pulses, unilateral electrode placement, and monitoring of treatment parameters has also become more widespread to enhance treatment efficacy and minimize side effects. However, there are still areas for improvement, such as promoting ECT education among psychiatrists and psychiatry residents.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2022)
Review
Biology
Kevin Lee, Kimberly D. Jenkins, Tanaya Sparkle
Summary: Electroconvulsive therapy (ECT) is an effective treatment for severe psychiatric disorders, and providing appropriate anesthesia for ECT is challenging, requiring consideration of the patient's condition and associated risks.
Article
Clinical Neurology
Hong Li, Lingzhi Hou, Dong Wang, Qijin Wu, Haijin Li, Wen He, Sheng Li, Jianyue Pang, Yanyan Zhang, Quangang Ma, Cai Li, Jun Cheng
Summary: This study found that the combination of antidepressants and electroconvulsive therapy (ECT) is highly effective and safe for treating depression in both adolescents and adults. Depressed adolescents expressed stronger suicidal intent, which was alleviated by ECT. There were no significant differences in depression symptoms and treatment outcomes between adolescents and adults, and the side effects were similar.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Nujaree Sombatcharoen-non, Thidarat Yamnim, Sudawan Jullagate, Pichai Ittasakul
Summary: This retrospective mirror-image study found that continuation-maintenance electroconvulsive therapy (ECT) can effectively reduce psychiatric hospitalizations and admission days in Thai patients with various psychiatric diagnoses.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2023)
Article
Clinical Neurology
Santiago Madero, Gerard Anmella, Maria Sague-Vilavella, Maria Teresa Pons, Anna Gimenez, Andrea Murru, Marta Gomez-Ramiro, Joaquin Gil-Badenes, Jose Rios, Miquel Bioque, Eduard Vieta, Antonio Benabarre
Summary: This study aimed to investigate the real-life effectiveness of maintenance electroconvulsive therapy(mECT) in bipolar disorder(BD). The results showed that mECT can effectively reduce the number and duration of psychiatric hospitalizations in BD patients, supporting its effectiveness in the treatment of BD.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Santiago Madero, Gerard Anmella, Maria Sague-Vilavella, Maria Teresa Pons, Anna Gimenez, Andrea Murru, Marta Gomez-Ramiro, Joaquin Gil-Badenes, Jose Rios, Miquel Bioque, Eduard Vieta, Antonio Benabarre
Summary: This study aimed to investigate the effectiveness of maintenance electroconvulsive therapy (mECT) in treating bipolar disorder (BD). The results showed that mECT had a 62.2% effectiveness in preventing psychiatric hospitalizations and significantly reduced the number of hospitalization days and admissions for BD patients.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Medicine, General & Internal
Randall T. Espinoza, Charles H. Kellner
Summary: Update on Electroconvulsive Therapy (ECT): ECT is effective for several disorders, notably severe or treatment-resistant depression, showing rapid response. However, stigma hampers its usage. The mechanism remains unknown, but a seizure is necessary for efficacy. ECT prominently affects memory, albeit transiently.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Psychiatry
Isabel Methfessel, Matthias Besse, Michael Belz, David Zilles-Wegner
Summary: This study found that reducing or discontinuing c-/m-ECT treatment can lead to significant clinical deterioration, including rehospitalizations and new courses of ECT. During the COVID-19 pandemic, modifications to treatment plans had a significant impact on the clinical outcomes of patients.
ACTA PSYCHIATRICA SCANDINAVICA
(2021)
Article
Medicine, General & Internal
Virginie Moulier, Julien Guehl, Emilie Eveque-Mourroux, Pierre Quesada, Maud Rotharmel
Summary: The objective of this study was to determine the relationship between clinical response and postictal suppression indicators during ECT treatment. The results showed that postictal suppression from the first ECT session can predict long-term clinical response, but not early clinical response. Postictal suppression frequency was not associated with clinical response, and there was also no association between postictal suppression and short-term cognitive performance.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
V. Millischer, S. Pramhas, I. Wiedermann, V. Eder, H. G. Kress, A. Michalek-Sauberer, D. Rujescu, R. Frey, P. Baldinger-Melich
Summary: This retrospective study compared the effects of etomidate and methohexital as anesthetic agents in ECT treatment. The results showed that etomidate was inferior to methohexital, as it led to longer procedure duration and poor side effects.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Biochemistry & Molecular Biology
Zhi-De Deng, Miklos Argyelan, Jeremy Miller, Davin K. Quinn, Megan Lloyd, Thomas R. Jones, Joel Upston, Erik Erhardt, Shawn M. McClintock, Christopher C. Abbott
Summary: This study investigates the mechanisms of ECT treatment and highlights a linear relationship between right hippocampal E-field strength, neuroplasticity, antidepressant outcomes, and cognitive results. Additionally, it reveals a direct correlation between right hippocampal E-field and cognitive outcomes.
MOLECULAR PSYCHIATRY
(2022)
Article
Psychiatry
Abhiram Narasimhan Purohith, Shalaka Anand Chatorikar, Samir Kumar Praharaj, Rajeshkrishna Panambur Bhandary, Podila Satya Venkata Narasimha Sharma
Summary: Maintenance electroconvulsive therapy may be a safe and effective treatment option for long-term management of treatment-resistant schizophrenia.
ASIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Psychiatry
Neera Ghaziuddin, Tareq Yaqub, Wael Shamseddeen, Priyanka Reddy, Hannah Reynard, Daniel Maixner
Summary: The study aimed to investigate the naturalistic clinical course in adolescent and young adult patients with developmental delays and catatonia, when maintenance electroconvulsive therapy (M-ECT) frequency was reduced due to COVID-19 restrictions. Participants showed significant decline in symptoms, particularly motor symptoms, leading to rehospitalization for some patients.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Clinical Neurology
Anna Z. Antosik-Wojcinska, Monika Dominiak, Pawel Mierzejewski, Piotr Jazdzyk, Gabor Gazdag, Rozalia Takacs, Adam Wichniak
Summary: The frequency of ECT use in Poland remains very low, with about 39.6% of psychiatric inpatient centers utilizing ECT, mainly for affective disorders. While safety measures have improved, the main reasons for not using ECT are insufficient funding and lack of experienced staff.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2021)
Review
Psychology, Multidisciplinary
Marco M. Zierhut, Renaldo M. Bernard, Eleanor Turner, Sara Mohamad, Eric Hahn, Malek Bajbouj
Summary: ECT holds promise as a treatment option for negative symptoms in schizophrenia, but the existing evidence is limited and methodological shortcomings are present. Future research should focus on negative symptoms, include longer follow up periods, incorporate control groups, and possibly establish multicentered studies to improve the study population.
CURRENT PSYCHOLOGY
(2023)
Review
Behavioral Sciences
Shane P. Gill, Charles H. Kellner
Letter
Behavioral Sciences
Charles H. Kellner, Sara M. Romanella
Editorial Material
Behavioral Sciences
Sara M. Romanella, Charles H. Kellner
Article
Medicine, Research & Experimental
Sanjay J. Mathew, Samuel T. Wilkinson, Murat Altinay, Ali Asghar-Ali, Lee C. Chang, Katherine A. Collins, Roman M. Dale, Bo Hu, Kamini Krishnan, Charles H. Kellner, Donald A. Malone, James W. Murrough, Robert B. Ostroff, Gerard Sanacora, Mingyuan Shao, Amit Anand
CONTEMPORARY CLINICAL TRIALS
(2019)
Letter
Anesthesiology
David A. Kellner, Charles H. Kellner
JOURNAL OF CLINICAL ANESTHESIA
(2019)
Editorial Material
Behavioral Sciences
Charles H. Kellner, Navjot Brainch, Camila Albuquerque
Article
Geriatrics & Gerontology
Sarah H. Lisanby, Shawn M. McClintock, George Alexopoulos, Samuel H. Bailine, Elisabeth Bernhardt, Mimi C. Briggs, C. Munro Cullum, Zhi-De Deng, Mary Dooley, Emma T. Geduldig, Robert M. Greenberg, Mustafa M. Husain, Styliani Kaliora, Rebecca G. Knapp, Vassilios Latoussakis, Lauren S. Liebman, William V. McCall, Martina Mueller, Georgios Petrides, Joan Prudic, Peter B. Rosenquist, Matthew V. Rudorfer, Shirlene Sampson, Abeba A. Teklehaimanot, Kristen G. Tobias, Richard D. Weiner, Robert C. Young, Charles H. Kellner
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2020)
Letter
Anesthesiology
Soren D. Ostergaard, Charles H. Kellner
Article
Psychiatry
C. H. Kellner, J. Obbels, P. Sienaert
ACTA PSYCHIATRICA SCANDINAVICA
(2020)
Editorial Material
Behavioral Sciences
Ethan O. Bryson, Amy Starr Aloysi
Article
Psychiatry
Linnea Stenmark, Charles H. Kellner, Mikael Landen, Irya Larsson, Mussie Msghina, Axel Nordenskjold
Summary: The study found that ECT may reduce the risk of psychiatric readmission in certain subgroups of patients with MDD, but there seems to be an increased readmission risk trend for patients under 35 years old.
ACTA PSYCHIATRICA SCANDINAVICA
(2021)
Review
Psychiatry
Joey P. A. J. Verdijk, Mike A. van Kessel, Matthijs Oud, Charles H. Kellner, Jeannette Hofmeijer, Esmee Verwijk, Jeroen A. van Waarde
Summary: This study conducted a systematic review and meta-analysis to explore pharmacological interventions to diminish cognitive side effects of ECT, with memantine and liothyronine showing promise for further research. The evidence quality was found to be low due to variations in ECT techniques, study populations, and cognitive measurements. Future research should focus on clarifying the pathophysiological mechanisms of ECT-induced cognitive side effects.
ACTA PSYCHIATRICA SCANDINAVICA
(2022)
Letter
Biochemistry & Molecular Biology
David Zilles-Wegner, Charles H. Kellner, Alexander Sartorius
MOLECULAR PSYCHIATRY
(2022)
Article
Anesthesiology
G. Burnett, R. A. Fry, E. O. Bryson
Review
Anesthesiology
Ethan O. Bryson
INTERNATIONAL ANESTHESIOLOGY CLINICS
(2020)
