Article
Clinical Neurology
Jose Fidel Baizabal-Carvallo, Marlene Alonso-Juarez, Joseph Jankovic
Summary: This study found that 17% of patients with TS exhibit SIB, which is associated with complex motor tics, OCD, and severity of tics.
JOURNAL OF NEUROLOGY
(2022)
Article
Clinical Neurology
Jose Fidel Baizabal-Carvallo, Marlene Alonso-Juarez, Joseph Jankovic
Summary: This study reviewed the medical records and video recordings of 155 TS patients and found that 26.5% of them had OM tics. Compared to classic tardive dyskinesia, OM tics have different manifestations and are more commonly associated with oromandibular and eye-rolling movements. Therefore, it is important to differentiate between the two.
JOURNAL OF NEUROLOGY
(2023)
Article
Clinical Neurology
Simon Morand-Beaulieu, Michael J. Crowley, Heidi Grantz, James F. Leckman, Lawrence Scahill, Denis G. Sukhodolsky
Summary: Comprehensive Behavioral Intervention for Tics (CBIT) is an effective treatment for Tourette syndrome (TS), but its underlying brain mechanisms are not well understood. This study found no association between EEG coherence during a Go/NoGo task and CBIT outcome, suggesting that the brain processes involved in motor response inhibition may not play a role in CBIT.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Clinical Neurology
Tamara Pringsheim, Christos Ganos, Christelle Nilles, Andrea E. E. Cavanna, Donald L. L. Gilbert, Erica Greenberg, Andreas Hartmann, Tammy Hedderly, Isobel Heyman, Holan Liang, Irene Malaty, Osman Malik, Nanette Mol Debes, Kirsten Muller Vahl, Alexander Munchau, Tara Murphy, Peter Nagy, Tamsin Owen, Renata Rizzo, Liselotte Skov, Jeremy Stern, Natalia Szejko, Yulia Worbe, Davide Martino
Summary: In 2020, there was a significant increase in referrals for young people with rapid onset of severe tic-like behaviors. A working group was formed to develop clinical criteria for the diagnosis of functional tic-like behaviors (FTLBs) to aid in recognition and diagnosis by healthcare professionals.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Review
Clinical Neurology
James Peters, Nirosen Vijiaratnam, Heather Angus-Leppan
Summary: This study reviewed the clinical spectrum of tic disorders induced by AED, including the types of AED implicated and the characteristics of the symptoms. The analysis revealed that multiple AEDs can induce tic disorders, suggesting that the cause is unlikely to be solely related to alterations in a single neurotransmitter, but rather a network imbalance influenced by various factors.
JOURNAL OF NEUROLOGY
(2021)
Article
Clinical Neurology
Jose Fidel Baizabal-Carvallo, Marlene Alonso-Juarez, Joseph Jankovic
Summary: Tics are rapid, recurrent, non-rhythmic movements or emitted sounds. This study compared tics associated with Tourette syndrome (TS) and secondary tic disorders (STD). It found that patients with TS had a younger age at onset, more severe and complex tics, and involvement of cranial-cervical muscles. Simple phonic tics showed the highest diagnostic accuracy for TS, but there was overlap in tic types and comorbidities between TS and STD patients.
JOURNAL OF NEURAL TRANSMISSION
(2023)
Review
Psychology, Developmental
Veit Roessner, Heike Eichele, Jeremy S. Stern, Liselotte Skov, Renata Rizzo, Nanette Mol Debes, Peter Nagy, Andrea E. Cavanna, Cristiano Termine, Christos Ganos, Alexander Muenchau, Natalia Szejko, Danielle Cath, Kirsten R. Mueller-Vahl, Cara Verdellen, Andreas Hartmann, Aribert Rothenberger, Pieter J. Hoekstra, Kerstin J. Plessen
Summary: The first European guidelines for Tourette Syndrome (TS) were published in 2011 by the European Society for the Study of Tourette Syndrome (ESSTS). The updated part on pharmacological treatment emphasizes the importance of psychoeducation and behavioral approaches as first-line treatments. Pharmacological treatment, particularly with dopamine blocking agents like aripiprazole, is indicated in some patients, especially when behavioral approaches are not effective or feasible. Treatment should be individualized based on the patient's needs, preferences, and co-existing conditions.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2022)
Article
Multidisciplinary Sciences
Payton Beeler, Nicholas O. Jensen, Soyoung Kim, Amy Robichaux-Viehoever, Bradley L. Schlaggar, Deanna J. Greene, Kevin J. Black, Rajan K. Chakrabarty
Summary: The study confirms the fractal nature of tics, indicating correlation between neighboring time scales. The fractal dimension is correlated with tic severity and serves as a sensitive parameter for examining the effects of tic suppression conditions. This finding opens up new possibilities for utilizing the fractal nature of tics as a tool for assessing and treating tic disorders.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2022)
Article
Psychology, Multidisciplinary
Stine Iversen, Arvid Nikolai Kildahl
Summary: Autistic individuals without intellectual disabilities may not be diagnosed until adolescence/adulthood. Misdiagnosis of autism as personality disorder (PD) may occur due to co-occurring self-injury, depression, and attention deficit disorder (ADD), as well as lack of comprehensive assessment and autism knowledge in general mental health services.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Nutrition & Dietetics
Chang-Chun Wu, Lee-Chin Wong, Chia-Jui Hsu, Chianne-Wen Yang, Ying-Chieh Tsai, Feng-Shiang Cheng, Hsiao-Yun Hu, Wang-Tso Lee
Summary: The study suggests that probiotics may not reduce tics in children with Tourette syndrome, but they may benefit comorbidities such as attention deficit and hyperactivity disorder. Further research is needed to clarify the effects of probiotics on the comorbidities of Tourette syndrome children.
Article
Behavioral Sciences
Adele M. Dimian, Annette Estes, Stephen Dager, Joseph J. Piven, Jason Wolff, IBIS Network
Summary: Self-injurious behavior (SIB) is common in individuals with autism spectrum disorder (ASD) and can occur at different ages. Previous research has shown a link between SIB at 12 months and SIB at 24 months. This study extends these findings by examining SIB occurrence and associated risk factors at 36 months. The results show that a diagnosis of ASD, SIB at 12 months, stereotypy, hyper- and hypo- sensory responsivity, and lower intellectual functioning are significant predictors of SIB at 36 months.
Review
Psychology, Developmental
Natalia Szejko, Sally Robinson, Andreas Hartmann, Christos Ganos, Nanette M. Debes, Liselotte Skov, Martina Haas, Renata Rizzo, Jeremy Stern, Alexander Munchau, Virginie Czernecki, Andrea Dietrich, Tara L. Murphy, Davide Martino, Zsanett Tarnok, Tammy Hedderly, Kirsten R. Muller-Vahl, Danielle C. Cath
Summary: This article presents an updated version 2.0 of European clinical guidelines for Tourette syndrome and other tic disorders, focusing on assessment. The guidelines were developed through thorough literature screening, national guidelines supplementation, and expert discussions within ESSTS. Diagnostic changes between DSM-IV and DSM-5 classifications, recommendations for rating scales, and new information on differential diagnoses are highlighted. Additionally, a recent survey among ESSTS members on assessment in TS is discussed.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2022)
Review
Clinical Neurology
Natalia Szejko, Kirsten R. Muller-Vahl
Summary: Tourette syndrome (TS) is characterized by vocal and motor tics, often accompanied by psychiatric comorbidities. Differential diagnosis between tics and OCD-related phenomena can be challenging, as some symptoms may overlap. "Just right" phenomena are common in patients with TS, showing similarities with both tics and OCD. Treatment strategies for tics and OCD in TS patients should take into consideration these complexities.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2021)
Article
Clinical Neurology
Jose Fidel Baizabal-Carvallo, Joseph Jankovic
Summary: This study aimed to characterize the frequency and features of blocking tics in patients with Tourette syndrome (TS). The results showed that approximately 6% of patients had blocking phenomena, with phonic tic intrusion causing speech arrest being the most common. Variables such as shoulder tics, leg tics, copropraxia, dystonic tics, simple phonic tics, and number of phonic tics per patient were statistically related to blocking phenomena. The presence of dystonic tics and a higher number of phonic tics were associated with blocking phenomena.
JOURNAL OF MOVEMENT DISORDERS
(2023)
Article
Clinical Neurology
Justyna Kaczynska, Piotr Janik
Summary: This study evaluated the prevalence, age of onset, and clinical correlates of blocking tics (BTs) in patients with Gilles de la Tourette syndrome (GTS). BTs represent early and common symptoms of GTS, associated with a more severe form of the syndrome.
FRONTIERS IN NEUROLOGY
(2021)