PEG-detachable cationic polyaspartamide derivatives bearing stearoyl moieties for systemic siRNA delivery toward subcutaneous BxPC3 pancreatic tumor

In situ quantitative monitoring of polyplexes and polyplex micelles in the blood circulation using intravital real-time confocal laser scanning microscopy

(2011) Takahiro Nomoto et al.   JOURNAL OF CONTROLLED RELEASE

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Target specific tumor treatment by VEGF siRNA complexed with reducible polyethyleneimine–hyaluronic acid conjugate

(2010) Kitae Park et al.   BIOMATERIALS

Reducible DNA nanoparticles enhance in vitro gene transfer via an extracellular mechanism

(2010) Wenchao Sun et al.   JOURNAL OF CONTROLLED RELEASE

Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp(DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown

(2010) Hyun Jin Kim et al.   JOURNAL OF CONTROLLED RELEASE

Direct and instantaneous observation of intravenously injected substances using intravital confocal micro-videography

(2010) Yu Matsumoto et al.   Biomedical Optics Express

Reduction-sensitive polymers and bioconjugates for biomedical applications

(2009) Fenghua Meng et al.   BIOMATERIALS

Minireview: Delivering the Code: Polyplex Carriers for Deoxyribonucleic Acid and Ribonucleic Acid Interference Therapies

(2009) R. James Christie et al.   ENDOCRINOLOGY

RNA interference as an anticancer therapy: a patent perspective

(2009) Derek M Dykxhoorn   EXPERT OPINION ON THERAPEUTIC PATENTS

Applications of RNA interference in cancer therapeutics as a powerful tool for suppressing gene expression

(2009) Song He et al.   MOLECULAR BIOLOGY REPORTS

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Biosignal-sensitive polyion complex micelles for the delivery of biopharmaceuticals

(2009) Yan Lee et al.   Soft Matter

Investigating the Effect of Increasing Charge Density on the Hemolytic Activity of Synthetic Antimicrobial Polymers

(2008) Zoha M. AL-Badri et al.   BIOMACROMOLECULES

Environment-Responsive Block Copolymer Micelles with a Disulfide Cross-Linked Core for Enhanced siRNA Delivery

(2008) Satoru Matsumoto et al.   BIOMACROMOLECULES

Recent development of nonviral gene delivery systems with virus-like structures and mechanisms

(2008) Keiji Itaka et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer

(2008) Sun Hwa Kim et al.   JOURNAL OF CONTROLLED RELEASE

Polyplexes from Poly(aspartamide) Bearing 1,2-Diaminoethane Side Chains Induce pH-Selective, Endosomal Membrane Destabilization with Amplified Transfection and Negligible Cytotoxicity

(2008) Kanjiro Miyata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PEG-Detachable Polyplex Micelles Based on Disulfide-Linked Block Catiomers as Bioresponsive Nonviral Gene Vectors

(2008) Seiji Takae et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Oncogene Silencing and Metastasis Inhibition via Systemic Delivery of siRNA

(2008) Shyh-Dar Li et al.   MOLECULAR THERAPY