Single-molecule kinetics and footprinting of DNA bis-intercalation: the paradigmatic case of Thiocoraline

Thiocoraline activates the Notch pathway in carcinoids and reduces tumor progression in vivo

(2014) T P Wyche et al.   CANCER GENE THERAPY

Strong DNA deformation required for extremely slow DNA threading intercalation by a binuclear ruthenium complex

(2014) Ali A. Almaqwashi et al.   NUCLEIC ACIDS RESEARCH

Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity

(2014) Zenita Adhireksan et al.   Nature Communications

Electrostatic Binding and Hydrophobic Collapse of Peptide–Nucleic Acid Aggregates Quantified Using Force Spectroscopy

(2013) Joan Camunas-Soler et al.   ACS Nano

Orthogonal Chemistry for the Synthesis of Thiocoraline–Triostin Hybrids. Exploring their Structure–Activity Relationship

(2013) Judit Tulla-Puche et al.   JOURNAL OF MEDICINAL CHEMISTRY

Elastic properties and secondary structure formation of single-stranded DNA at monovalent and divalent salt conditions

(2013) Alessandro Bosco et al.   NUCLEIC ACIDS RESEARCH

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

(2013) Baoxu Pang et al.   Nature Communications

Force spectroscopy reveals the DNA structural dynamics that govern the slow binding of Actinomycin D

(2012) Thayaparan Paramanathan et al.   NUCLEIC ACIDS RESEARCH

Dynamics and Multiple Stable Binding Modes of DNA Intercalators Revealed by Single-Molecule Force Spectroscopy

(2011) D. Hern Paik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A sequence-specific threading tetra-intercalator with an extremely slow dissociation rate constant

(2011) Garen G. Holman et al.   Nature Chemistry

The kinetics of YOYO-1 intercalation into single molecules of double-stranded DNA

(2010) Marcel Reuter et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Recent developments in bisintercalator natural products

(2010) Olga E. Zolova et al.   BIOPOLYMERS

Torsional sensing of small-molecule binding using magnetic tweezers

(2010) J. Lipfert et al.   NUCLEIC ACIDS RESEARCH

Mechanical and structural properties of YOYO-1 complexed DNA

(2010) K. Gunther et al.   NUCLEIC ACIDS RESEARCH

Single-molecule derivation of salt dependent base-pair free energies in DNA

(2010) J. M. Huguet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction of Oxazole Yellow Dyes with DNA Studied with Hybrid Optical Tweezers and Fluorescence Microscopy

(2009) C.U. Murade et al.   BIOPHYSICAL JOURNAL

Binding Kinetics of Bisintercalator Triostin A with Optical Tweezers Force Mechanics

(2009) Christoph Kleimann et al.   BIOPHYSICAL JOURNAL

High-resolution dynamic mapping of histone-DNA interactions in a nucleosome

(2009) Michael A Hall et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Statistical Properties of Metastable Intermediates in DNA Unzipping

(2009) J. M. Huguet et al.   PHYSICAL REVIEW LETTERS

Allosteric modulation of DNA by small molecules

(2009) D. M. Chenoweth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging

(2009) J. van Mameren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative DNase footprint titration: a tool for analyzing the energetics of protein–DNA interactions

(2008) Keith D Connaghan-Jones et al.   Nature Protocols

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE