Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining

DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells

(2014) Sehyun Oh et al.   DNA REPAIR

Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair

(2014) Mansour Akbari et al.   DNA REPAIR

Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining

(2014) Aashish Soni et al.   NUCLEIC ACIDS RESEARCH

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair

(2014) Ismail Abdou et al.   NUCLEIC ACIDS RESEARCH

Structure and function of the DNA ligases encoded by the mammalian LIG3 gene

(2013) Alan E. Tomkinson et al.   GENE

Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source

(2013) Scott Classen et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Mitochondrial DNA Ligase Is Dispensable for the Viability of Cultured Cells but Essential for mtDNA Maintenance

(2013) Inna N. Shokolenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Catalytic Region of DNA Ligase IV in Complex with an Artemis Fragment Sheds Light on Double-Strand Break Repair

(2013) Takashi Ochi et al.   STRUCTURE

The Maintenance of Mitochondrial DNA Integrity--Critical Analysis and Update

(2013) M. Alexeyev et al.   Cold Spring Harbor Perspectives in Biology

Conformational transitions of proteins engaged in DNA double-strand break repair, analysed by tryptophan fluorescence emission and FRET

(2012) Katia Stankova et al.   BIOCHEMICAL JOURNAL

Involvement of DNA ligase III and ribonuclease H1 in mitochondrial DNA replication in cultured human cells

(2011) Heini Ruhanen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Disconnecting XRCC1 and DNA ligase III

(2011) Sachin Katyal et al.   CELL CYCLE

Kinetic Mechanism of Human DNA Ligase I Reveals Magnesium-dependent Changes in the Rate-limiting Step That Compromise Ligation Efficiency

(2011) Mark R. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA

(2011) Marie-France Langelier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Abnormal DNA Repair in Therapy-Resistant Breast Cancers

(2011) L. A. Tobin et al.   MOLECULAR CANCER RESEARCH

Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

(2011) Deniz Simsek et al.   NATURE

DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair

(2011) Yankun Gao et al.   NATURE

DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation

(2011) Deniz Simsek et al.   PLoS Genetics

Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching between Two DNA-Bound States

(2010) Elizabeth Cotner-Gohara et al.   BIOCHEMISTRY

Targeting abnormal DNA double strand break repair in cancer

(2010) Feyruz V. Rassool et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)

(2009) Greg L Hura et al.   NATURE METHODS

Eukaryotic DNA Ligases: Structural and Functional Insights

(2008) Tom Ellenberger et al.   Annual Review of Biochemistry

Two DNA-binding and Nick Recognition Modules in Human DNA Ligase III

(2008) Elizabeth Cotner-Gohara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks

(2008) L. Liang et al.   NUCLEIC ACIDS RESEARCH