Liver X receptors bridge hepatic lipid metabolism and inflammation

Activation of Liver X Receptors Attenuates Endotoxin-Induced Liver Injury in Mice with Nonalcoholic Fatty Liver Disease

(2011) Yuan Liu et al.   DIGESTIVE DISEASES AND SCIENCES

Nonalcoholic Fatty Liver Disease: Pathology and Pathogenesis

(2010) Dina G. Tiniakos et al.   Annual Review of Pathology-Mechanisms of Disease

LXRα regulates human CETP expression in vitro and in transgenic mice

(2010) Shoko Honzumi et al.   ATHEROSCLEROSIS

Intestinal Specific LXR Activation Stimulates Reverse Cholesterol Transport and Protects from Atherosclerosis

(2010) Giuseppe Lo Sasso et al.   Cell Metabolism

Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C

(2010) Elena Lima-Cabello et al.   CLINICAL SCIENCE

Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice

(2010) Kristiaan Wouters et al.   FEBS LETTERS

Liver X receptor agonism promotes articular inflammation in murine collagen-induced arthritis

(2009) Darren L. Asquith et al.   ARTHRITIS AND RHEUMATISM

Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF- B signalling

(2009) S. Wu et al.   CARDIOVASCULAR RESEARCH

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

(2009) S. Ghisletti et al.   GENES & DEVELOPMENT

Induction of SREBP-1c mRNA by Differentiation and LXR Ligand in Human Keratinocytes

(2009) Ai Yokoyama et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

LIVER X RECEPTOR AGONIST GW3965 DOSE-DEPENDENTLY REGULATES LPS-MEDIATED LIVER INJURY AND MODULATES POSTTRANSCRIPTIONAL TNF-α PRODUCTION AND P38 MITOGEN-ACTIVATED PROTEIN KINASE ACTIVATION IN LIVER MACROPHAGES

(2009) Yun Yong Wang et al.   SHOCK

HDL, ABC Transporters, and Cholesterol Efflux: Implications for the Treatment of Atherosclerosis

(2008) Alan R. Tall et al.   Cell Metabolism

Activation of Liver X Receptors Promotes Neuroprotection and Reduces Brain Inflammation in Experimental Stroke

(2008) Jesús R. Morales et al.   CIRCULATION

Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors

(2008) Cynthia Hong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Hepatic triglyceride synthesis and nonalcoholic fatty liver disease

(2008) Steve S Choi et al.   CURRENT OPINION IN LIPIDOLOGY

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

(2008) Kristiaan Wouters et al.   HEPATOLOGY

Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease

(2008) Nobito Higuchi et al.   HEPATOLOGY RESEARCH

Structure-Guided Design ofN-Phenyl Tertiary Amines as Transrepression-Selective Liver X Receptor Modulators with Anti-Inflammatory Activity

(2008) Esther Y. Chao et al.   JOURNAL OF MEDICINAL CHEMISTRY

PXR and LXR in Hepatic Steatosis: A New Dog and an Old Dog with New Tricks

(2007) Jung Hoon Lee et al.   MOLECULAR PHARMACEUTICS