Chemo-enzymatic synthesis of site-specific isotopically labeled nucleotides for use in NMR resonance assignment, dynamics and structural characterizations

The NMR structure of the II–III–VI three-way junction from theNeurosporaVS ribozyme reveals a critical tertiary interaction and provides new insights into the global ribozyme structure

(2015) Eric Bonneau et al.   RNA

Structure of the HIV-1 RNA packaging signal

(2015) S. C. Keane et al.   SCIENCE

Regio-Selective Chemical-Enzymatic Synthesis of Pyrimidine Nucleotides Facilitates RNA Structure and Dynamics Studies

(2014) Luigi J. Alvarado et al.   CHEMBIOCHEM

13Cα CEST experiment on uniformly 13C-labeled proteins

(2014) Yang Zhou et al.   JOURNAL OF BIOMOLECULAR NMR

Off-resonance rotating-frame relaxation dispersion experiment for 13C in aromatic side chains using L-optimized TROSY-selection

(2014) Ulrich Weininger et al.   JOURNAL OF BIOMOLECULAR NMR

Effects of J couplings and unobservable minor states on kinetics parameters extracted from CEST data

(2014) Yang Zhou et al.   JOURNAL OF MAGNETIC RESONANCE

Flipping of the Ribosomal A-Site Adenines Provides a Basis for tRNA Selection

(2014) Xiancheng Zeng et al.   JOURNAL OF MOLECULAR BIOLOGY

The 3' Untranslated Region of Pea Enation Mosaic Virus Contains Two T-Shaped, Ribosome-Binding, Cap-Independent Translation Enhancers

(2014) F. Gao et al.   JOURNAL OF VIROLOGY

A structure-based mechanism for tRNA and retroviral RNA remodelling during primer annealing

(2014) Sarah B. Miller et al.   NATURE

Measuring hydrogen exchange rates in invisible protein excited states

(2014) D. Long et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR

(2014) R. B. Fenwick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing Slow Chemical Exchange at Carbonyl Sites in Proteins by Chemical Exchange Saturation Transfer NMR Spectroscopy

(2013) Pramodh Vallurupalli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Computational Study of the Effects of13C-13C Scalar Couplings on13C CEST NMR Spectra: Towards Studies on a Uniformly13C-Labeled Protein

(2013) Pramodh Vallurupalli et al.   CHEMBIOCHEM

Probing slowly exchanging protein systems via 13Cα-CEST: monitoring folding of the Im7 protein

(2013) Alexandar L. Hansen et al.   JOURNAL OF BIOMOLECULAR NMR

Visualizing Side Chains of Invisible Protein Conformers by Solution NMR

(2013) Guillaume Bouvignies et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterizing Slow Chemical Exchange in Nucleic Acids by Carbon CEST and Low Spin-Lock Field R1ρ NMR Spectroscopy

(2013) Bo Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Three-state mechanism couples ligand and temperature sensing in riboswitches

(2013) Anke Reining et al.   NATURE

NMR paves the way for atomic level descriptions of sparsely populated, transiently formed biomolecular conformers

(2013) A. Sekhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

13C relaxation experiments for aromatic side chains employing longitudinal- and transverse-relaxation optimized NMR spectroscopy

(2012) Ulrich Weininger et al.   JOURNAL OF BIOMOLECULAR NMR

Conformational exchange of aromatic side chains characterized by L-optimized TROSY-selected 13C CPMG relaxation dispersion

(2012) Ulrich Weininger et al.   JOURNAL OF BIOMOLECULAR NMR

Identification of a Minimal Region of the HIV-1 5′-Leader Required for RNA Dimerization, NC Binding, and Packaging

(2012) Xiao Heng et al.   JOURNAL OF MOLECULAR BIOLOGY

Probing Transient Hoogsteen Hydrogen Bonds in Canonical Duplex DNA Using NMR Relaxation Dispersion and Single-Atom Substitution

(2012) Evgenia N. Nikolova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of (6-13C)Pyrimidine Nucleotides as Spin-Labels for RNA Dynamics

(2012) Christoph H. Wunderlich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of the yeast U2/U6 snRNA complex

(2012) J. E. Burke et al.   RNA

Probing RNA dynamics via longitudinal exchange and CPMG relaxation dispersion NMR spectroscopy using a sensitive 13C-methyl label

(2011) Karin Kloiber et al.   NUCLEIC ACIDS RESEARCH

Multiple conformations of SAM-II riboswitch detected with SAXS and NMR spectroscopy

(2011) Bin Chen et al.   NUCLEIC ACIDS RESEARCH

Widespread Genetic Switches and Toxicity Resistance Proteins for Fluoride

(2011) J. L. Baker et al.   SCIENCE

Time-resolved structural studies of protein reaction dynamics: a smorgasbord of X-ray approaches

(2010) Sebastian Westenhoff et al.   ACTA CRYSTALLOGRAPHICA SECTION A

Selective 13C labeling of nucleotides for large RNA NMR spectroscopy using an E. coli strain disabled in the TCA cycle

(2010) Chandar S. Thakur et al.   JOURNAL OF BIOMOLECULAR NMR

Site-specific labeling of nucleotides for making RNA for high resolution NMR studies using an E. coli strain disabled in the oxidative pentose phosphate pathway

(2010) T. Kwaku Dayie et al.   JOURNAL OF BIOMOLECULAR NMR

Structure of a Conserved Retroviral RNA Packaging Element by NMR Spectroscopy and Cryo-Electron Tomography

(2010) Yasuyuki Miyazaki et al.   JOURNAL OF MOLECULAR BIOLOGY

Solution structure of the cap-independent translational enhancer and ribosome-binding element in the 3' UTR of turnip crinkle virus

(2010) X. Zuo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isotope labeling strategies for NMR studies of RNA

(2009) Kun Lu et al.   JOURNAL OF BIOMOLECULAR NMR

Extending the Range of Microsecond-to-Millisecond Chemical Exchange Detected in Labeled and Unlabeled Nucleic Acids by Selective Carbon R1ρNMR Spectroscopy

(2009) Alexandar L. Hansen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pathway Engineered Enzymaticde NovoPurine Nucleotide Synthesis

(2008) Heather L. Schultheisz et al.   ACS Chemical Biology

Stereospecificity, substrate, and inhibitory properties of nucleoside diphosphate analogs for creatine and pyruvate kinases

(2008) Charlotta K. Wennefors et al.   BIOORGANIC CHEMISTRY

Key Labeling Technologies to Tackle Sizeable Problems in RNA Structural Biology

(2008) Kwaku Dayie   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Measurement of carbonyl chemical shifts of excited protein states by relaxation dispersion NMR spectroscopy: comparison between uniformly and selectively 13C labeled samples

(2008) Patrik Lundström et al.   JOURNAL OF BIOMOLECULAR NMR

Solution structure of tRNAVal from refinement of homology model against residual dipolar coupling and SAXS data

(2008) Alexander Grishaev et al.   JOURNAL OF BIOMOLECULAR NMR

Stochastic Gating and Drug–Ribosome Interactions

(2008) Andrea C. Vaiana et al.   JOURNAL OF MOLECULAR BIOLOGY

Extensive Backbone Dynamics in the GCAA RNA Tetraloop Analyzed Using13C NMR Spin Relaxation and Specific Isotope Labeling

(2008) James E. Johnson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY