An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex

Alternative Splicing of MBD2 Supports Self-Renewal in Human Pluripotent Stem Cells

(2014) Yu Lu et al.   Cell Stem Cell

Insight into the Architecture of the NuRD Complex

(2014) Saad S. M. Alqarni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting the disordered C terminus of PTP1B with an allosteric inhibitor

(2014) Navasona Krishnan et al.   Nature Chemical Biology

Solution structure and intramolecular exchange of methyl-cytosine binding domain protein 4 (MBD4) on DNA suggests a mechanism to scan for mCpG/TpG mismatches

(2014) Ninad M. Walavalkar et al.   NUCLEIC ACIDS RESEARCH

Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease

(2014) Gergely Tóth et al.   PLoS One

Transcriptional Repressor Domain of MBD1 is Intrinsically Disordered and Interacts with its Binding Partners in a Selective Manner

(2014) Umar Farook Shahul Hameed et al.   Scientific Reports

Transcription onset of genes critical in liver carcinogenesis is epigenetically regulated by methylated DNA-binding protein MBD2

(2013) Barbara Stefanska et al.   CARCINOGENESIS

Probing the Dynamic Distribution of Bound States for Methylcytosine-binding Domains on DNA

(2013) Jason M. Cramer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An androgen receptor N-terminal domain antagonist for treating prostate cancer

(2013) Jae-Kyung Myung et al.   JOURNAL OF CLINICAL INVESTIGATION

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

(2013) Christopher J. Millard et al.   MOLECULAR CELL

Unique Features of the Anti-parallel, Heterodimeric Coiled-coil Interaction between Methyl-cytosine Binding Domain 2 (MBD2) Homologues and GATA Zinc Finger Domain Containing 2A (GATAD2A/p66α)

(2012) Ninad M. Walavalkar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation

(2012) Hideharu Hashimoto et al.   NUCLEIC ACIDS RESEARCH

Stoichiometry of chromatin-associated protein complexes revealed by label-free quantitative mass spectrometry-based proteomics

(2012) Arne H. Smits et al.   NUCLEIC ACIDS RESEARCH

Intrinsically disordered proteins: a 10-year recap

(2012) Peter Tompa   TRENDS IN BIOCHEMICAL SCIENCES

MBD2 contributes to developmental silencing of the human ε-globin gene

(2011) Jeremy W. Rupon et al.   BLOOD CELLS MOLECULES AND DISEASES

Intrinsically disordered proteins from A to Z

(2011) Vladimir N. Uversky   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Sequence correction of random coil chemical shifts: correlation between neighbor correction factors and changes in the Ramachandran distribution

(2011) Magnus Kjaergaard et al.   JOURNAL OF BIOMOLECULAR NMR

Fuzziness: linking regulation to protein dynamics

(2011) Monika Fuxreiter   Molecular BioSystems

Methyl-Binding Domain Protein 2-Dependent Proliferation and Survival of Breast Cancer Cells

(2011) O. Y. Mian et al.   MOLECULAR CANCER RESEARCH

Solution structure and dynamic analysis of chicken MBD2 methyl binding domain bound to a target-methylated DNA sequence

(2011) J. Neel Scarsdale et al.   NUCLEIC ACIDS RESEARCH

p66 -MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2-NuRD complex

(2011) M. N. Gnanapragasam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique Physical Properties and Interactions of the Domains of Methylated DNA Binding Protein 2

(2010) Rajarshi P. Ghosh et al.   BIOCHEMISTRY

Nrf2 Expression Is Regulated by Epigenetic Mechanisms in Prostate Cancer of TRAMP Mice

(2010) Siwang Yu et al.   PLoS One

CpG islands - ‘A rough guide’

(2009) Robert S. Illingworth et al.   FEBS LETTERS

Multiple Independent Binding Sites for Small-Molecule Inhibitors on the Oncoprotein c-Myc

(2009) Dalia I. Hammoudeh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Developmental programming of CpG island methylation profiles in the human genome

(2009) Ravid Straussman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Epigenetic mechanisms in mammals

(2008) J. K. Kim et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE

Unmasking of epigenetically silenced candidate tumor suppressor genes by removal of methyl-CpG-binding domain proteins

(2008) L Lopez-Serra et al.   ONCOGENE

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain

(2008) M. Wells et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modern analytical ultracentrifugation in protein science: A tutorial review

(2002) Jacob Lebowitz et al.   PROTEIN SCIENCE