RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1

Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1

(2015) Julie S. Barber-Rotenberg et al.   Oncotarget

Pharmacokinetic modeling optimizes inhibition of the ‘undruggable’ EWS-FLI1 transcription factor in Ewing Sarcoma

(2015) Sung-Hyeok Hong et al.   Oncotarget

Helicase associated 2 domain is essential for helicase activity of RNA helicase A

(2014) Li Xing et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Hepatitis Delta Antigen Requires a Flexible Quasi-Double-Stranded RNA Structure To Bind and Condense Hepatitis Delta Virus RNA in a Ribonucleoprotein Complex

(2014) B. L. Griffin et al.   JOURNAL OF VIROLOGY

Repetitive RNA unwinding by RNA helicase A facilitates RNA annealing

(2014) Hye Ran Koh et al.   NUCLEIC ACIDS RESEARCH

catRAPID omics: a web server for large-scale prediction of protein-RNA interactions

(2013) F. Agostini et al.   BIOINFORMATICS

RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an E -myc/Bcl-2 mouse model

(2013) J. R. Mills et al.   BLOOD

DHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cells

(2013) A. Jain et al.   NUCLEIC ACIDS RESEARCH

Structure-function analysis of the EF-hand protein centrin-2 for its intracellular localization and nucleotide excision repair

(2013) R. Nishi et al.   NUCLEIC ACIDS RESEARCH

Cofactor-dependent specificity of a DEAD-box protein

(2013) C. L. Young et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of RNA Helicase Brr2 by the C-Terminal Tail of the Spliceosomal Protein Prp8

(2013) S. Mozaffari-Jovin et al.   SCIENCE

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Structure, function and regulation of spliceosomal RNA helicases

(2012) Olivier Cordin et al.   CURRENT OPINION IN CELL BIOLOGY

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Cis-acting noncoding RNAs: friends and foes

(2012) Sònia Guil et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions

(2012) Keith F. Decker et al.   NUCLEIC ACIDS RESEARCH

Cellular RNA helicases and HIV-1: Insights from genome-wide, proteomic, and molecular studies

(2012) Chia-Yen Chen et al.   VIRUS RESEARCH

An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma

(2011) Pavel Sumazin et al.   CELL

High-Resolution Genome-wide Mapping of the Primary Structure of Chromatin

(2011) Zhenhai Zhang et al.   CELL

Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and Its Regulation by Upf2

(2011) Sutapa Chakrabarti et al.   MOLECULAR CELL

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Human DHX9 Helicase Unwinds Triple-Helical DNA Structures

(2010) Aklank Jain et al.   BIOCHEMISTRY

Prp43p contains a processive helicase structural architecture with a specific regulatory domain

(2010) Hélène Walbott et al.   EMBO JOURNAL

Structural basis for the function of DEAH helicases

(2010) Yangzi He et al.   EMBO REPORTS

Coordinate Roles of Gag and RNA Helicase A in Promoting the Annealing of Formula to HIV-1 RNA

(2010) L. Xing et al.   JOURNAL OF VIROLOGY

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase

(2010) Prasun Chakraborty et al.   NUCLEIC ACIDS RESEARCH

eIF4G stimulates the activity of the DEAD box protein eIF4A by a conformational guidance mechanism

(2010) Manuel Hilbert et al.   NUCLEIC ACIDS RESEARCH

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis

(2009) Simon Lebaron et al.   EMBO JOURNAL

Hepatitis Delta Antigen Requires a Minimum Length of the Hepatitis Delta Virus Unbranched Rod RNA Structure for Binding

(2009) D. A. Defenbaugh et al.   JOURNAL OF VIROLOGY

Prp43 Bound at Different Sites on the Pre-rRNA Performs Distinct Functions in Ribosome Synthesis

(2009) Markus T. Bohnsack et al.   MOLECULAR CELL

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

(2009) Hayriye V Erkizan et al.   NATURE MEDICINE

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner

(2009) Holger von Moeller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The neurofibromatosis type I pre-mRNA is a novel target of CELF protein-mediated splicing regulation

(2009) Victoria A. Barron et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Structure of the C-terminus of the mRNA export factor Dbp5 reveals the interaction surface for the ATPase activator Gle1

(2009) Z. Y. Dossani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mRNA Export Factor Gle1 and Inositol Hexakisphosphate Regulate Distinct Stages of Translation

(2008) Timothy A. Bolger et al.   CELL

Translation Initiation on Mammalian mRNAs with Structured 5′UTRs Requires DExH-Box Protein DHX29

(2008) Vera P. Pisareva et al.   CELL

EWS/FLI1 suppresses retinoblastoma protein function and senescence in Ewing's sarcoma cells

(2008) Hsien-Ming Hu et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Genetically defined EWS/FLI1 model system suggests mesenchymal origin of Ewing's family tumors

(2008) Gary Potikyan et al.   LABORATORY INVESTIGATION

The SWISS-MODEL Repository and associated resources

(2008) F. Kiefer et al.   NUCLEIC ACIDS RESEARCH

Oncogenic role of DDX3 in breast cancer biogenesis

(2008) M Botlagunta et al.   ONCOGENE

Crystal structure of the yeast eIF4A-eIF4G complex: An RNA-helicase controlled by protein-protein interactions

(2008) P. Schutz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA