Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage

LSD1 Overexpression Is Associated with Poor Prognosis in Basal-Like Breast Cancer, and Sensitivity to PARP Inhibition

(2015) Satoi Nagasawa et al.   PLoS One

Protein Kinase CK2 and Angiogenesis

(2015) Mathias Montenarh   Advances in Clinical and Experimental Medicine

The lysine-specific demethylase 1 is a novel substrate of protein kinase CK2

(2014) Roberto Costa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

SET8 methyltransferase activity during the DNA double-strand break response is required for recruitment of 53BP1

(2014) S. Dulev et al.   EMBO REPORTS

PTIP associates with Artemis to dictate DNA repair pathway choice

(2014) Jiadong Wang et al.   GENES & DEVELOPMENT

High expression of the histone demethylase LSD1 associates with cancer cell proliferation and unfavorable prognosis in tongue cancer

(2014) Chunping Yuan et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

The genomic landscape of nasopharyngeal carcinoma

(2014) De-Chen Lin et al.   NATURE GENETICS

HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability

(2014) Min Zhu et al.   NUCLEIC ACIDS RESEARCH

Crosstalk between ubiquitin and other post-translational modifications on chromatin during double-strand break repair

(2014) Yu Zhao et al.   TRENDS IN CELL BIOLOGY

Silencing of the DNA Mismatch Repair Gene MLH1 Induced by Hypoxic Stress in a Pathway Dependent on the Histone Demethylase LSD1

(2014) Yuhong Lu et al.   Cell Reports

Protein kinase CK2 is required for the recruitment of 53BP1 to sites of DNA double-strand break induced by radiomimetic drugs

(2013) Barbara Guerra et al.   CANCER LETTERS

The histone demethylase LSD1/KDM1A promotes the DNA damage response

(2013) Nima Mosammaparast et al.   JOURNAL OF CELL BIOLOGY

RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection

(2013) J. Ross Chapman et al.   MOLECULAR CELL

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

(2013) Amélie Fradet-Turcotte et al.   NATURE

Double-strand break repair: 53BP1 comes into focus

(2013) Stephanie Panier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks

(2013) M. Bohgaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching

(2013) M. Di Virgilio et al.   SCIENCE

Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair

(2013) K.-Y. Hsiao et al.   Journal of Molecular Cell Biology

The Deubiquitinase USP28 Stabilizes LSD1 and Confers Stem-Cell-like Traits to Breast Cancer Cells

(2013) Yadi Wu et al.   Cell Reports

Response to DNA damage: why do we need to focus on protein phosphatases?

(2013) Midori Shimada et al.   Frontiers in Oncology

Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage

(2012) Birgitte B Olsen et al.   BMC MOLECULAR BIOLOGY

RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling

(2012) Francesca Mattiroli et al.   CELL

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

(2012) Frédérick A Mallette et al.   EMBO JOURNAL

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Overexpression of lysine specific demethylase 1 predicts worse prognosis in primary hepatocellular carcinoma patients

(2012) Ze-Kun Zhao   WORLD JOURNAL OF GASTROENTEROLOGY

A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

(2011) Sebastian A. Wagner et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of DNA End Joining, Resection, and Immunoglobulin Class Switch Recombination by 53BP1

(2011) Anne Bothmer et al.   MOLECULAR CELL

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

(2011) Huadong Pei et al.   NATURE

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

(2011) Klara Acs et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

LSD1 is required for chromosome segregation during mitosis

(2010) Shuang Lv et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

PTIP promotes DNA double-strand break repair through homologous recombination

(2010) Xin Wang et al.   GENES TO CELLS

Wild-type p53-induced Phosphatase 1 Dephosphorylates Histone Variant γ-H2AX and Suppresses DNA Double Strand Break Repair

(2010) Sung-Hwan Moon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

(2010) Kyle M Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Wip1 phosphatase is associated with chromatin and dephosphorylates γH2AX to promote checkpoint inhibition

(2010) L Macůrek et al.   ONCOGENE

PTIP Promotes Chromatin Changes Critical for Immunoglobulin Class Switch Recombination

(2010) J. A. Daniel et al.   SCIENCE

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin

(2008) Fredrik Melander et al.   JOURNAL OF CELL BIOLOGY