Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses

Arterivirus nsp12 versus the coronavirus nsp16 2′-O-methyltransferase: comparison of the C-terminal cleavage products of two nidovirus pp1ab polyproteins

(2015) Kathleen C. Lehmann et al.   JOURNAL OF GENERAL VIROLOGY

What we know but do not understand about nidovirus helicases

(2015) Kathleen C. Lehmann et al.   VIRUS RESEARCH

Coronaviruses: Important Emerging Human Pathogens

(2014) C. M. Coleman et al.   JOURNAL OF VIROLOGY

Characterization of an Alphamesonivirus 3C-Like Protease Defines a Special Group of Nidovirus Main Proteases

(2014) S. Blanck et al.   JOURNAL OF VIROLOGY

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Database resources of the National Center for Biotechnology Information

(2014)   NUCLEIC ACIDS RESEARCH

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

(2014) Lorenzo Subissi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Does form meet function in the coronavirus replicative organelle?

(2014) Benjamin W. Neuman et al.   TRENDS IN MICROBIOLOGY

From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses

(2013) Rolf Hilgenfeld et al.   ANTIVIRAL RESEARCH

SARS-CoV ORF1b-encoded nonstructural proteins 12–16: Replicative enzymes as antiviral targets

(2013) Lorenzo Subissi et al.   ANTIVIRAL RESEARCH

RefSeq: an update on mammalian reference sequences

(2013) Kim D. Pruitt et al.   NUCLEIC ACIDS RESEARCH

Pfam: the protein families database

(2013) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

The Footprint of Genome Architecture in the Largest Genome Expansion in RNA Viruses

(2013) Chris Lauber et al.   PLoS Pathogens

Mesoniviridae: a proposed new family in the order Nidovirales formed by a single species of mosquito-borne viruses

(2012) Chris Lauber et al.   ARCHIVES OF VIROLOGY

Biochemical characterization of a recombinant SARS coronavirus nsp12 RNA-dependent RNA polymerase capable of copying viral RNA templates

(2012) Dae-Gyun Ahn et al.   ARCHIVES OF VIROLOGY

Partitioning the Genetic Diversity of a Virus Family: Approach and Evaluation through a Case Study of Picornaviruses

(2012) C. Lauber et al.   JOURNAL OF VIROLOGY

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Highly similar structural frames link the template tunnel and NTP entry tunnel to the exterior surface in RNA-dependent RNA polymerases

(2012) Dorothy M. Lang et al.   NUCLEIC ACIDS RESEARCH

GenBank

(2012) Dennis A. Benson et al.   NUCLEIC ACIDS RESEARCH

RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex

(2012) M. Bouvet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates

(2012) A. K. Chakravarty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

(2011) Roland Züst et al.   NATURE IMMUNOLOGY

HHblits: lightning-fast iterative protein sequence searching by HMM-HMM alignment

(2011) Michael Remmert et al.   NATURE METHODS

Conventional and unconventional mechanisms for capping viral mRNA

(2011) Etienne Decroly et al.   NATURE REVIEWS MICROBIOLOGY

HMMER web server: interactive sequence similarity searching

(2011) R. D. Finn et al.   NUCLEIC ACIDS RESEARCH

Analysis of RNA Binding by the Dengue Virus NS5 RNA Capping Enzyme

(2011) Brittney R. Henderson et al.   PLoS One

Coronaviruses

(2011) Mark R. Denison et al.   RNA Biology

The genome-linked protein VPg of plant viruses—a protein with many partners

(2011) Jun Jiang et al.   Current Opinion in Virology

Discovery of the First Insect Nidovirus, a Missing Evolutionary Link in the Emergence of the Largest RNA Virus Genomes

(2011) Phan Thi Nga et al.   PLoS Pathogens

Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex

(2011) Yu Chen et al.   PLoS Pathogens

Practical application of bioinformatics by the multidisciplinary VIZIER consortium

(2010) Alexander E. Gorbalenya et al.   ANTIVIRAL RESEARCH

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

Arterivirus Nsp1 Modulates the Accumulation of Minus-Strand Templates to Control the Relative Abundance of Viral mRNAs

(2010) Danny D. Nedialkova et al.   PLoS Pathogens

Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture

(2010) Aartjan J. W. te Velthuis et al.   PLoS Pathogens

In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation

(2010) Mickaël Bouvet et al.   PLoS Pathogens

pGenTHREADER and pDomTHREADER: new methods for improved protein fold recognition and superfamily discrimination

(2009) Anna Lobley et al.   BIOINFORMATICS

SNAD: sequence name annotation-based designer

(2009) Igor A Sidorov et al.   BMC BIOINFORMATICS

Adenylate-forming enzymes

(2009) Stefan Schmelz et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Biochemical Characterization of Arterivirus Nonstructural Protein 11 Reveals the Nidovirus-Wide Conservation of a Replicative Endoribonuclease

(2009) D. D. Nedialkova et al.   JOURNAL OF VIROLOGY

Coronaviruses post-SARS: update on replication and pathogenesis

(2009) Stanley Perlman et al.   NATURE REVIEWS MICROBIOLOGY

The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

(2009) Aartjan J. W. te Velthuis et al.   NUCLEIC ACIDS RESEARCH

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

(2009) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure

(2009) M. Issur et al.   RNA

Self-guanylylation of birnavirus VP1 does not require an intact polymerase activity site

(2009) Junhua Pan et al.   VIROLOGY

Euprosterna elaeasa virus genome sequence and evolution of the Tetraviridae family: Emergence of bipartite genomes and conservation of the VPg signal with the dsRNA Birnaviridae family

(2009) Jean-Louis Zeddam et al.   VIROLOGY

Reverse genetic characterization of the natural genomic deletion in SARS-Coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein in-vitro and in-vivo

(2009) Susanne Pfefferle et al.   Virology Journal

Coronavirus Nonstructural Protein 16 Is a Cap-0 Binding Enzyme Possessing (Nucleoside-2'O)-Methyltransferase Activity

(2008) E. Decroly et al.   JOURNAL OF VIROLOGY

The Jpred 3 secondary structure prediction server

(2008) C. Cole et al.   NUCLEIC ACIDS RESEARCH