NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress

Loss of glutathione peroxidase 7 promotes TNF-α-induced NF-κB activation in Barrett’s carcinogenesis

(2014) Dun-Fa Peng et al.   CARCINOGENESIS

A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins

(2014) T. Afroz et al.   GENES & DEVELOPMENT

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA recognition and self-association of CPEB4 is mediated by its tandem RRM domains

(2014) Constanze Schelhorn et al.   NUCLEIC ACIDS RESEARCH

Glutathione Peroxidase 7 Suppresses Bile Salt-Induced Expression of Pro-Inflammatory Cytokines in Barrett's Carcinogenesis

(2014) Dun-Fa Peng et al.   Journal of Cancer

Glutathione Peroxidase 7 Utilizes Hydrogen Peroxide Generated by Ero1α to Promote Oxidative Protein Folding

(2013) Lei Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human

(2013) Yi-Cheng Chang et al.   EMBO Molecular Medicine

Glutathione peroxidase 7 has potential tumour suppressor functions that are silenced by location-specific methylation in oesophageal adenocarcinoma

(2013) DunFa Peng et al.   GUT

The C-Terminal Region of Cytoplasmic Polyadenylation Element Binding Protein Is a ZZ Domain with Potential for Protein–Protein Interactions

(2013) Daniel J. Merkel et al.   JOURNAL OF MOLECULAR BIOLOGY

Deletion of CPEB3 Enhances Hippocampus-Dependent Memory via Increasing Expressions of PSD95 and NMDA Receptors

(2013) Hsu-Wen Chao et al.   JOURNAL OF NEUROSCIENCE

CPEB4 Knockout Mice Exhibit Normal Hippocampus-Related Synaptic Plasticity and Memory

(2013) Li-Yun Tsai et al.   PLoS One

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Abstract 4652: The autophagy-senescence connection in chemotherapy of breast tumor cells; senescence accelerated by autophagy but not dependent on autophagy

(2012) Rachel W. Goehe et al.   CANCER RESEARCH

Abstract 3187:Ex vivocharacterization of CTCs isolated using the FMSA device

(2012) Hairong Cheng et al.   CANCER RESEARCH

Calpain 2 Activated through N-Methyl-D-Aspartic Acid Receptor Signaling Cleaves CPEB3 and Abrogates CPEB3-Repressed Translation in Neurons

(2012) C.-F. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Loss of the Oxidative Stress Sensor NPGPx Compromises GRP78 Chaperone Activity and Induces Systemic Disease

(2012) Pei-Chi Wei et al.   MOLECULAR CELL

Neuralized1 Activates CPEB3: A Function for Nonproteolytic Ubiquitin in Synaptic Plasticity and Memory Storage

(2011) Elias Pavlopoulos et al.   CELL

Mitochondrial Complex III ROS Regulate Adipocyte Differentiation

(2011) Kathryn V. Tormos et al.   Cell Metabolism

Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking

(2011) Todd J Cohen et al.   EMBO JOURNAL

CPEB2-eEF2 interaction impedes HIF-1α RNA translation

(2011) Po-Jen Chen et al.   EMBO JOURNAL

Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells

(2011) DunFa Peng et al.   GUT

Two Endoplasmic Reticulum PDI Peroxidases Increase the Efficiency of the Use of Peroxide during Disulfide Bond Formation

(2011) Van Dat Nguyen et al.   JOURNAL OF MOLECULAR BIOLOGY

Key contribution of CPEB4-mediated translational control to cancer progression

(2011) Elena Ortiz-Zapater et al.   NATURE MEDICINE

Non-targeting siRNA induces NPGPx expression to cooperate with exoribonuclease XRN2 for releasing the stress

(2011) P.-C. Wei et al.   NUCLEIC ACIDS RESEARCH

A direct way of redox sensing

(2011) Roger Benoit et al.   RNA Biology

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

Meiosis requires a translational positive loop where CPEB1 ensues its replacement by CPEB4

(2010) Ana Igea et al.   EMBO JOURNAL

Lifespan and oxidative stress show a non-linear response to atmospheric oxygen in Drosophila

(2010) B. Rascon et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

The X-ray Crystal Structure of the First RNA Recognition Motif and Site-Directed Mutagenesis Suggest a Possible HuR Redox Sensing Mechanism

(2010) Roger Marc Benoit et al.   JOURNAL OF MOLECULAR BIOLOGY

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Mitochondrial glutathione peroxidase 4 disruption causes male infertility

(2009) Manuela Schneider et al.   FASEB JOURNAL

Hypoxia-inducible factor-1α has a key role in hypoxic preconditioning

(2009) Satoshi Taie et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Cysteine Oxidation Regulates the RNA-Binding Activity of Iron Regulatory Protein 2

(2009) K. B. Zumbrennen et al.   MOLECULAR AND CELLULAR BIOLOGY

Evolutionary and Structural Insights Into the Multifaceted Glutathione Peroxidase (Gpx) Superfamily

(2008) Stefano Toppo et al.   ANTIOXIDANTS & REDOX SIGNALING

Cytoplasmic polyadenylation-element-binding protein (CPEB)1 and 2 bind to theHIF-1α mRNA 3′-UTR and modulate HIF-1α protein expression

(2008) Sonja Hägele et al.   BIOCHEMICAL JOURNAL

Oxidative Stress Is Inherent in Prostate Cancer Cells and Is Required for Aggressive Phenotype

(2008) B. Kumar et al.   CANCER RESEARCH

HIF-1 regulation: not so easy come, easy go

(2008) Mei Yee Koh et al.   TRENDS IN BIOCHEMICAL SCIENCES