Identifying high-affinity aptamer ligands with defined cross-reactivity using high-throughput guided systematic evolution of ligands by exponential enrichment

Large scale analysis of the mutational landscape in HT-SELEX improves aptamer discovery

(2015) Jan Hoinka et al.   NUCLEIC ACIDS RESEARCH

Emulsion PCR Significantly Improves Nonequilibrium Capillary Electrophoresis of Equilibrium Mixtures-Based Aptamer Selection: Allowing for Efficient and Rapid Selection of Aptamer to Unmodified ABH2 Protein

(2014) Roman Yufa et al.   ANALYTICAL CHEMISTRY

Quantitative selection and parallel characterization of aptamers

(2013) M. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selection Strategy to Generate Aptamer Pairs that Bind to Distinct Sites on Protein Targets

(2012) Qiang Gong et al.   ANALYTICAL CHEMISTRY

Isolation and Optimization of Murine IL-10 Receptor Blocking Oligonucleotide Aptamers Using High-throughput Sequencing

(2012) Alexey Berezhnoy et al.   MOLECULAR THERAPY

What's fueling the biotech engine—2011 to 2012

(2012) Saurabh Aggarwal   NATURE BIOTECHNOLOGY

Rapid Identification of Cell-Specific, Internalizing RNA Aptamers with Bioinformatics Analyses of a Cell-Based Aptamer Selection

(2012) William H. Thiel et al.   PLoS One

Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse Viruses

(2012) D. R. Burton et al.   SCIENCE

Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts

(2011) Xiaohua Ni et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras

(2011) Lee Adam Wheeler et al.   JOURNAL OF CLINICAL INVESTIGATION

Emulsion PCR: A High Efficient Way of PCR Amplification of Random DNA Libraries in Aptamer Selection

(2011) Keke Shao et al.   PLoS One

An Aptamer-siRNA Chimera Suppresses HIV-1 Viral Loads and Protects from Helper CD4+ T Cell Decline in Humanized Mice

(2011) C. P. Neff et al.   Science Translational Medicine

Rational Truncation of an RNA Aptamer to Prostate-Specific Membrane Antigen Using Computational Structural Modeling

(2011) William M. Rockey et al.   Nucleic Acid Therapeutics

Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay

(2010) Fernando Pastor et al.   NATURE

Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing

(2010) M. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

(2009) Justin P Dassie et al.   NATURE BIOTECHNOLOGY

Variants of the Antibody Herceptin That Interact with HER2 and VEGF at the Antigen Binding Site

(2009) J. Bostrom et al.   SCIENCE