Article
Materials Science, Multidisciplinary
Y. Say, N. Aslan, A. M. A. Alla, H. Ozmen
Summary: Different chemical media were used to chemically etch the surface of 316L SS steel, and the effects on surface roughness, degradation, and ion release were investigated. The HNO3, H2SO4, and HCl media did not significantly react with the steel surface, while different phases were observed with HClO4, NaOH, and Na2CO3. Roughness did not correlate with concentration or immersion time, and degradation and ion release were not affected by roughness. H2SO4 etching resulted in the highest ion release.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Pharmacology & Pharmacy
Tomoya Yoshikawa, Jumpei Oki, Natsumi Ichikawa, Shinji Yamashita, Kiyohiko Sugano
Summary: This study investigated the impact of small pH differences on the dissolution equivalence of branded and generic drug products containing an acidic drug salt, finding significant differences in dissolution profiles among the products under different acidic pH conditions. Multiple acidic pH conditions should be considered for ensuring dissolution equivalence.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Medicine, Research & Experimental
Xiaoyu Liu, Qingqing Tan, Jiaqi Wen, Xufei Wang, Gang Yang, Yuxiao Li, Ming Lu, Wei Ye, Anfeng Si, Sujuan Ma, Tong Ding, Luan Sun, Fang Liu, Mei Zhang, Tao Jiang, Wei Gao
Summary: This study found that a pH-sensitive antibody-based immunotoxin degrades faster in lysosomes, leading to effective toxin release and improved antitumor activity. These findings suggest that a pH-sensitive antibody may have an advantage in the design of immunotoxins and other lysosomal degradation-dependent antibody conjugate drugs.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Chemistry, Multidisciplinary
Laura Wimberger, Joakim Andreasson, Jonathon E. Beves
Summary: This article introduces a new type of merocyanine photoacid with superior pH switching qualities. It demonstrates the ability to achieve reversible pH changes under visible light induction and significantly lower pH values from alkaline to acidic environments.
CHEMICAL COMMUNICATIONS
(2022)
Article
Multidisciplinary Sciences
Qingbo Zhang, Yue Hu, Caitlin M. Masterson, Wonhee Jang, Zhen Xiao, Arash Bohloul, Daniel Garcia-Rojas, Hema L. Puppala, George Bennett, Vicki L. Colvin
Summary: This study characterized the dissolution process and associated biological activity of silver nanoparticles with different dimensions, shapes, and surface chemistries. A quantitative model was developed to relate material structure to silver dissolution and microbial toxicity. The results showed that shape had the most profound influence on antibacterial activity, while surface coatings had the least impact.
Article
Chemistry, Multidisciplinary
Anyang Chen, Mengting Deng, Zhiyi Lu, Yichao Lin, Liang Chen
Summary: Proton exchange membrane (PEM)-based water electrolysis currently uses iridium (Ir) as the anodic catalyst, and ultrafine metallic Ir nanoparticles have attracted attention due to their high acidic oxygen evolution reaction (OER) activity. In this study, we report the preparation of ultrafine metallic iridium electrocatalyst (UF-Ir/IrOx) without surfactants via a surfactant-free hydrothermal reaction. During the OER, UF-Ir/IrOx undergoes significant structural reconstruction and exhibits outstanding acidic OER activity and stability by following the adsorbate evolution mechanism (AEM), as revealed by X-ray photoelectron spectroscopy (XPS) and in situ Raman characterization.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Article
Engineering, Environmental
Jasim Zia, Giorgio Mancini, Matteo Bustreo, Arkadiusz Zych, Roberto Donno, Athanassia Athanassiou, Despina Fragouli
Summary: This article presents the development of biobased colorimetric pH porous indicators composed of anthocyanins from red cabbage, polyvinyl alcohol, polyvinyl pyrrolidone, and microcrystalline cellulose. The inclusion of microcrystalline cellulose in the composite enhances stability, porosity, interconnectivity, and responsiveness to acidic or basic vapors. The color changes are reversible and easily perceivable through visual analysis, demonstrating potential applications in environmental protection and intelligent food packaging.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Engineering, Chemical
Matthew Essandoh, Rafael A. Garcia, Victoria L. Palochik, Makahra R. Gayle, Chen Liang
Summary: Magnetized, polypeptidylated hemoglobin was successfully used for the simultaneous adsorption of acidic and basic dyes. The adsorption behavior followed pseudo-second order kinetics, with Langmuir isotherm model accurately describing the adsorption effect. Furthermore, the stability of the adsorbent under neutral conditions and the negligible impact on adsorption capacity after multiple cycles of dye desorbing regeneration treatment were observed.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Agricultural Engineering
Jixiang Wang, Zejiao Li, Qian Wang, Xingyu Chen, Zhongfang Lei, Kazuya Shimizu, Zhenya Zhang, Yasuhisa Adachi, Duu-Jong Lee
Summary: This study aimed to investigate the mechanisms of Ca2+ release in a bacterial aerobic granular sludge (AGS) system. It was found that during the non-aeration (anaerobic) phase, there was a nearly 40% increase in Ca2+ concentration at the bottom of the AGS reactor, accompanied by a decrease in pH and an increase in Mg2+ concentration. The dissolution of CaCO3 and the exchange of ions between Ca2+ and Mg2+ were identified as the major contributors to Ca2+ release during the anaerobic P release process.
BIORESOURCE TECHNOLOGY
(2023)
Article
Chemistry, Physical
Saikiran Khamgaonkar, Qiaoyun Chen, Kevin Musselman, Vivek Maheshwari
Summary: Polymer-integrated perovskite photocathodes with highly efficient and stable performance have been successfully fabricated and coupled with an Au-Pt-Ni bimetallic catalyst for hydrogen evolution in both acidic and alkaline conditions. The polymer-integrated photocathodes exhibited high hydrogen evolution photocurrent density (around 20 mA cm-2), high onset potential (around 0.95 V), and HC-STH (half-cell solar to hydrogen conversion efficiency) of 10.11%. Moreover, the stability of the perovskite photocathodes in sulfuric acid and potassium hydroxide was significantly improved by polymer additive engineering, greatly extending the device lifetime.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Chemistry, Physical
Saikiran Khamgaonkar, Qiaoyun Chen, Kevin Musselman, Vivek Maheshwari
Summary: Organolead halide perovskite photocathodes have shown great potential for photoelectrochemical hydrogen evolution, but their poor stability in aqueous environment and low HER performance in alkaline conditions have limited their practical application. In this study, highly efficient and stable polymer-integrated perovskite photocathodes are fabricated and coupled with Au-Pt-Ni bimetallic catalyst, resulting in improved hydrogen evolution performance.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Materials Science, Biomaterials
Liao Zhang, Shumin Hu, Leitao Zhang, Wenlan Wu, Qiuli Cheng, Junbo Li, Ravin Narain
Summary: The article describes a novel nano-therapeutic system, G4-AB, which has the capability to simultaneously convert its size and charge while targeting the acidic tumor microenvironment. The in vitro and in vivo experiments demonstrate that the G4-AB-DOX nano-therapeutic system has better antitumor efficiency and lower toxicity compared to free DOX or PEGylated PAMAM.
BIOMATERIALS SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Haneul Jin, Songa Choi, Gi Joo Bang, Taehyun Kwon, Hee Soo Kim, Su Ji Lee, Yongju Hong, Dong Wook Lee, Hyun S. Park, Hionsuck Baik, Yousung Jung, Sung Jong Yoo, Kwangyeol Lee
Summary: The study found that by controlling the mixture of Pt atoms with the RuO2 matrix in acidic water electrooxidation, the durability and activity of RuO2 can be improved, resulting in the preparation of highly efficient PtCo-RuO2/C nanorods. These nanorods show lower overpotential and strong mass activity in half-cell tests, while also exhibiting long-term stability. Additionally, Pt dopants promote the adsorption and deprotonation processes in the oxygen evolution reaction, thereby limiting Ru overoxidation.
ENERGY & ENVIRONMENTAL SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Luis A. Cipriano, Henrik H. Kristoffersen, Renan L. Munhos, Rebecca Pittkowski, Matthias Arenz, Jan Rossmeisl
Summary: The dissolution of nanoparticles under corrosive environments is a major issue in electrochemical processes. A model and experiments have shown that the use of an anti-corrosive element can partially stop the dissolution process of binary nanoparticles, with nanoparticle size and chemical composition playing a key role in the dissolution process.
Article
Engineering, Biomedical
Kelsey Hopkins, Elizabeth Wakelin, Natalie Romick, Jacqueline Kennedy, Emma Simmons, Luis Solorio
Summary: There is a need to reduce the frequency of injections for protein drugs, and in situ forming implants (ISFIs) have shown potential for controlled release. However, protein instability is a challenge due to the acidic microclimate within ISFIs. This study demonstrates that adding basic salts can neutralize the acidic environment, improving protein stability and the potential of ISFIs for delivering pH-sensitive biomolecules.
ANNALS OF BIOMEDICAL ENGINEERING
(2023)