Article
Multidisciplinary Sciences
Vinay Bhaskar, Sikander Saini, Shama Ansari, Shubham Ghai, Abhishek Thakur, Suman Chopra, Vivekananda Verma, Dhruba Malakar
Summary: This study aimed to cure chronic endometritis in buffalo using allogenic adipose-derived MSCs. AD-MSCs were isolated and characterized, and their safety and efficacy were assessed in vivo. AD-MSCs treatment significantly reduced inflammation in endometritic buffaloes and improved fertility rates.
SCIENTIFIC REPORTS
(2023)
Review
Agriculture, Dairy & Animal Science
Stephen J. LeBlanc
Summary: This paper reviews recent data and concepts on metritis, purulent vaginal discharge, and endometritis in dairy cows and their impact on reproductive performance. It discusses the causes, diagnosis, and treatment of these diseases, as well as the potential for improved management strategies.
Article
Pathology
Viviana Gonzalez-Astudillo, Javier Asin-Ros, Janet Moore, Francisco A. Uzal, Mauricio A. Navarro
Summary: This study investigated the association of P. sordellii with veterinary reproductive disease in goats. The retrospective search of a database identified 9 cases of goats with P. sordellii-associated metritis or endometritis, often co-colonized by Escherichia coli. The presence of copper deficiency in some cases suggests a possible influencing factor. This is the first report documenting the association of P. sordellii with veterinary gynecological disease.
VETERINARY PATHOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Maria Radanova, Mariya Levkova, Galya Mihaylova, Rostislav Manev, Margarita Maneva, Rossen Hadgiev, Nikolay Conev, Ivan Donev
Summary: There is a growing interest in studying single nucleotide polymorphisms (SNPs) in microRNA (miRNA) genes, as they may be associated with susceptibility, prognosis, and treatment response in colorectal cancer (CRC). These miRNA-SNPs could serve as non-invasive biomarkers for early detection of CRC. However, contradictory findings have been reported when different research groups investigated the same SNP in a gene for a specific miRNA, highlighting the need for more case-control studies involving participants from different ethnic backgrounds. According to our review, three miRNA-SNPs - miR-146a rs2910164, miR-27a rs895819, and miR-608 rs4919510 - appear to be promising prognostic, diagnostic, and predictive biomarkers for CRC.
Review
Plant Sciences
Zheng Ying, Muhammad Awais, Reshmi Akter, Fengjiao Xu, Sul Baik, Daehyo Jung, Deok Chun Yang, Gi-Young Kwak, Wenying You
Summary: Discriminating plant species, cultivars, and landraces is challenging, but SNP markers have proven to be a reliable tool for differentiating Panax ginseng and similar species. This article provides a cost-effective guide for SNP marker analysis in a traditional laboratory setting.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Cardiac & Cardiovascular Systems
Matthew R. Alexander, Samuel Hank, Bethany L. Dale, Lauren Himmel, Xue Zhong, Charles D. Smart, Daniel J. Fehrenbach, Yuhan Chen, Nitin Prabakaran, Brian Tirado, Megan Centrella, Mingfang Ao, Liping Du, Yu Shyr, Daniel Levy, Meena S. Madhur
Summary: Research suggests that the Trp encoding allele of rs3184504 may be causal for hypertension and renal dysfunction, in part due to the loss of SH2B3-mediated repression of T cell IL-12 signaling leading to enhanced IFNg production.
CIRCULATION RESEARCH
(2022)
Review
Agriculture, Dairy & Animal Science
Renan Braga Paiano, Pietro Sampaio Baruselli
Summary: This review provides an overview of alternative treatment strategies, such as plant extracts and essential oils, for controlling bovine uterine diseases, highlighting their advantages and limitations.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2022)
Article
Biochemistry & Molecular Biology
Justyna Basak, Danuta Piotrzkowska, Ireneusz Majsterek, Ewa Kucharska
Summary: Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system with no cure and unclear etiology. This study aimed to identify SNPs associated with an increased risk of developing MS. The findings suggest that the GG AGO1 rs636832 and AA GEMIN4 rs7813 genotypes are associated with an increased risk of MS.
Article
Immunology
Yan Li, Wei Li, Li Huang, Huijia Li, Peipeng He, Chao Xue
Summary: This study investigated the association between microscopic polyangiitis and the single nucleotide polymorphism rs807185 in autophagy-associated gene 4A (ATG4A) in the Chinese population. Using multiplex polymerase chain reaction and high-throughput sequencing, it was found that the control group had a higher frequency of the A allele of rs807185 compared to the microscopic polyangiitis group, suggesting that the A allele of rs807185 may have a protective effect against microscopic polyangiitis in the Chinese population. However, the molecular mechanisms remain unclear.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Article
Cell Biology
Concetta Scimone, Luigi Donato, Simona Alibrandi, Concetta Alafaci, Angela D'Ascola, Sergio Vinci, Rosalia D'Angelo, Antonina Sidoti
Summary: This study reveals the importance of epitranscriptomic modifications in gene expression regulation and suggests the involvement of altered epitranscriptome profile in the development of CCM. These findings provide new insights for further investigation into the pathogenesis of CCM.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
(2022)
Review
Cell Biology
Farbod Bahreini, Elham Rayzan, Nima Rezaei
Summary: Breast cancer, a multifactorial disease, may have an increased risk due to alterations in microRNA sequences. miR-SNPs are potential biomarkers for early detection of breast cancer.
JOURNAL OF CELLULAR PHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Jonas Schmidt, Sandro Berghaus, Frithjof Blessing, Holger Herbeck, Josef Blessing, Peter Schierack, Stefan Rodiger, Dirk Roggenbuck, Folker Wenzel
Summary: Nanopore sequencing has great potential for clinical diagnostics, but further validation and certification are required.
Article
Plant Sciences
Xi-ou Xiao, Ning Zhang, Hui Jin, Huaijun Si
Summary: This study evaluated the genetic diversity and population structure of 135 autotetraploid potatoes using SLAF-seq methods. Analysis of 3,397,137 high-quality SNPs revealed that the classification of these potatoes based on SNP profiles did not correlate with their geographical origins. Furthermore, 71 PARMS-SNP markers were successfully used to analyze 190 autotetraploid potato varieties. Overall, these novel SNP markers provide a solid foundation for potato genetic diversity analysis, DUS testing, and plant variety protection.
Article
Veterinary Sciences
Iftach Schouten, Andres Bernys-Karolys, Peleg Schneider, Tal Dror, Lior Ofer, Chen Shimoni, Einat Nissim-Eliraz, Nahum Y. Shpigel, Sharon Schlesinger
Summary: The use of mesenchymal stromal cells (MSCs) is a safe and effective treatment for infectious and non-infectious inflammatory diseases in both humans and animals. This study investigated the properties of MSCs and their potential in treating mastitis and metritis, common diseases in dairy cows. The results showed that MSC treatment reduced bacterial load and modulated the inflammatory response in the uterus and mammary gland. This opens new possibilities for the development of MSC-based cell-free therapies.
BMC VETERINARY RESEARCH
(2023)
Article
Medicine, General & Internal
Piotr Macek, Mieszko Wieckiewicz, Rafal Poreba, Pawel Gac, Katarzyna Bogunia-Kubik, Marta Dratwa, Anna Wojakowska, Grzegorz Mazur, Helena Martynowicz
Summary: This study investigated the relationship between SNP of the TERT gene and the severity of sleep bruxism, and identified the independent risk factors for sleep bruxism. The results showed that one SNP of TERT was associated with the episode index of phasic bruxism, and the lack of this SNP, male sex, and arterial hypertension were independent risk factors for phasic bruxism.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Agriculture, Dairy & Animal Science
P. Pinedo, J. E. P. Santos, R. C. Chebel, K. N. Galvao, G. M. Schuenemann, R. C. Bicalho, R. O. Gilbert, S. L. Rodriguez-Zas, C. M. Seabury, G. Rosa, W. Thatcher
JOURNAL OF DAIRY SCIENCE
(2020)
Article
Veterinary Sciences
Giorgia Podico, Robyn E. Ellerbrock, Bruna R. Curcio, Soon Hon Cheong, Fabio S. Lima, Igor F. Canisso
JOURNAL OF EQUINE VETERINARY SCIENCE
(2020)
Article
Agriculture, Dairy & Animal Science
M. A. Hannan, K. Murata, S. Takeuchi, S. Haneda, S. H. Cheong, Y. Nambo
DOMESTIC ANIMAL ENDOCRINOLOGY
(2020)
Article
Veterinary Sciences
Jennine Lection, Barbara Delvescovo, Aaron Percival, Timothy Wu, Teresa Southard, Mariana Diel de Amorim, Soon Hon Cheong
Summary: In utero fracture and malunion of long bones is rare in horses, often leading to abortion. This case presented a live foal with previous in utero fracture malunion, ultimately euthanized due to congenital abnormalities, shedding light on a new potential etiology for dystocia.
JOURNAL OF EQUINE VETERINARY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Jennine Lection, Alyssa J. Cornelius, Rachel Moxon, Jane Russenberger, Mariana Diel de Amorim, Soon Hon Cheong
Summary: This study aimed to report the incidence of mastitis and metritis in guide dog colonies and identify risk factors for these diseases. Risk factors for mastitis included colony, litter size, and mammary gland congestion, while no significant risk factors were identified for metritis due to the small number of cases analyzed. The results provide important parameters for breeders and veterinarians to monitor and prevent these conditions in female dogs.
ANIMAL REPRODUCTION SCIENCE
(2021)
Article
Veterinary Sciences
Lorenzo G. T. M. Segabinazzi, McKinsey Landers, Ava Kent, Erik Peterson, Robert Gilbert, Hilari French
Summary: This study evaluated the efficacy and side effects of different doses of cloprostenol sodium and dinoprost tromethamine in inducing luteolysis in jennies. Results showed that low doses of both drugs were effective in reducing the length of the estrous cycle with fewer adverse effects.
JOURNAL OF EQUINE VETERINARY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Reza Rajabi-Toustani, Hiroyuki Watanabe, Munkhtuul Tsogtgerel, Yuanzhi Gao, Li Canbo, Shingo Haneda, Soon Hon Cheong, Yasuo Nambo
Summary: The study aimed to improve the cryopreservation of large equine embryos with the assistance of PMAP and/or LAP, showing potential for enhancing success rates. While embryos under 300 micrometers benefited from laser-assisted puncture, further investigation is needed for embryos larger than 700 micrometers to determine the best method for successful pregnancy outcomes.
REPRODUCTION IN DOMESTIC ANIMALS
(2021)
Article
Agriculture, Dairy & Animal Science
D. Manriquez, W. W. Thatcher, J. E. P. Santos, R. C. Chebel, K. N. Galvao, G. M. Schuenemann, R. C. Bicalho, R. O. Gilbert, S. Rodriguez-Zas, C. M. Seabury, G. J. M. Rosa, P. Pinedo
Summary: This study investigated the effects of different levels of Delta BCS on fertility, milk yield, and survival of Holstein cows with specific health profiles. The results showed that Delta BCS had a significant impact on resumption of ovarian cyclicity and pregnancy outcomes, while cows with reproductive or other health disorders had differences in milk production and pregnancy success compared to healthy cows.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Developmental Biology
Viju Vijayan Pillai, Tiffany G. Kei, Shailesh Gurung, Moubani Das, Luiz G. B. Siqueira, Soon Hon Cheong, Peter J. Hansen, Vimal Selvaraj
Summary: TGF beta 1 plays a crucial role in the differentiation of trophoblast cells, and inhibition of RhoA/Rock promotes self-renewal and proliferation.
Article
Veterinary Sciences
Martha Hoffman, Soon Hon Cheong, Tracy Stokol
Summary: This study showed that clinically healthy neonatal foals may have transient increases in liver analytes, such as GLDH, SDH, and GGT activities, and total and indirect bilirubin concentrations, which do not necessarily indicate liver disease.
VETERINARY CLINICAL PATHOLOGY
(2023)
Article
Veterinary Sciences
Nicholas D. D. Walsh, Ian R. R. Porter, Allison V. V. Miller, Anthony J. J. Fischetti, Soon Hon Cheong, Peter V. V. Scrivani
Summary: This study design categorized a canine congenital intrahepatic portosystemic shunt (IPSS) into interlobar or intralobar based on its location within a liver fissure or lobe. An anatomic study provided a CT angiography (CTA) appearance of normal canine ductus venosus (DV) and confirmed its location between the papillary process and left-lateral liver lobe. A retrospective multi-institutional case series documented the frequency of IPSS in 56 dogs and classified them into interlobar and intralobar types. Documenting the location of an IPSS during canine portal CTA can enhance the consistency and validity of IPSS description.
VETERINARY RADIOLOGY & ULTRASOUND
(2023)
Article
Reproductive Biology
Abdallah Wagih Abdallah Abdelhady, Luis Henrique Aguiar, Yoke Lee Lee, Ziqi Guo, Rhasaan T. Bovell, Patrick L. Crane, Mariana Diel de Amorim, Soon Hon Cheong
Summary: The study investigates the effects of ROCKi treatment before or after cryopreservation on embryo viability. The results suggest that ROCKi can potentially improve the survival and development of bovine embryos.
Letter
Biochemistry & Molecular Biology
Angela R. Freeman, Danielle N. Lee, Jeremy J. Allen, Bryant Blank, Dean Jeffery, Assaf Lerer, Bhupinder Singh, Teresa Southard, Soon Hon Cheong, Alexander G. Ophir
Article
Agriculture, Dairy & Animal Science
Reza Rajabi-Toustani, Munkhtuul Tsogtgerel, Yuanzhi Gao, Canbo LI, Miou Sakato, Shingo Haneda, Soon Hon Cheong, Yasuo Nambo
Summary: Japanese native horses, which consist of 8 breeds, are threatened with extinction. Researchers successfully carried out embryo transfer using native ponies from Kiso and Hokkaido as donors and recipients. The embryos were transported a long distance, 1500 km over 9 hours, from Nagano Prefecture to Hokkaido in a container maintained at 22?. One mare delivered a healthy live foal after receiving two embryos. These results demonstrate the potential for the proliferation of Japanese native horses through reciprocal embryo transfer with long-distance transportation of fresh embryos.
JOURNAL OF REPRODUCTION AND DEVELOPMENT
(2023)
Article
Agriculture, Dairy & Animal Science
P. Pinedo, J. E. P. Santos, R. C. Chebel, K. N. Galvao, G. M. Schuenemann, R. C. Bicalho, R. O. Gilbert, S. Rodriguez Zas, C. M. Seabury, G. Rosa, W. W. Thatcher
JOURNAL OF DAIRY SCIENCE
(2020)