Review
Immunology
Katarzyna Dudek, Ewelina Szacawa, Robin A. J. Nicholas
Summary: Two important cattle diseases caused by mycoplasmas are Mycoplasma bovis and Mycoplasma mycoides subsp. mycoides. Current vaccines have limited effectiveness in combating these diseases, and there is a need for increased resources to improve vaccine coverage and reduce economic losses in the cattle industry caused by mycoplasmas.
Article
Microbiology
Monica Baquero, Ksenia Vulikh, Cassidy Wong, Meghan Domony, DeLenn Burrows, David Marom, Jose Perez-Casal, Hugh Y. Cai, Jeff L. Caswell
Summary: This study found that macrophages infected with M. bovis secrete MMP-12 and SPLA2, while pre-treatment with pro-inflammatory cytokines increased the secretion of cathepsin B in response to M. bovis infection. These results suggest that proteases, lipases, and cytokines derived from monocyte-derived macrophages may mediate how prior inflammation in the respiratory tract worsens disease outcomes from M. bovis infection.
VETERINARY MICROBIOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Vera Haapala, Nella Vahanikkila, Laura Kulkas, Erja Tuunainen, Tarja Pohjanvirta, Tiina Autio, Sinikka Pelkonen, Timo Soveri, Heli Simojoki
Summary: Control measures are necessary on dairy farms to minimize the risk of Mycoplasma bovis infection spread, which include identification and control of all possible risk factors associated with the infection. Implementing measures such as isolating calves and avoiding nose-to-nose contact can effectively reduce the risk of M. bovis infection according to the study findings.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Veterinary Sciences
Hui Zhang, Guyue Hu, Doukun Lu, Gang Zhao, Yiqiu Zhang, Muhammad Zubair, Yingyu Chen, Changmin Hu, Xi Chen, Jianguo Chen, Huanchun Chen, Liguo Yang, Aizhen Guo
Summary: This study compared the secretomes of virulent and attenuated strains of M.bovis to identify potential pathogenesis-related secreted proteins. Results showed 34 proteins were more abundant and uniquely expressed in the virulent strain, potentially associated with the virulence of M.bovis.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
C. McAloon, C. G. McAloon, J. Tratalos, L. O'Grady, G. McGrath, M. Guelbenzu, D. A. Graham, K. O'Keeffe, D. J. Barrett, S. J. More
Summary: This study estimated the apparent herd prevalence of Mycoplasma bovis in Irish dairy herds using bulk milk surveillance samples. The results showed a high apparent herd prevalence of seropositivity to M. bovis in Irish dairy herds. The study also identified risk factors associated with positive herd status, indicating the endemic nature of M. bovis infection in the Irish dairy sector.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Microbiology
Robert Valeris-Chacin, Sherri Powledge, Taylor McAtee, Paul S. S. Morley, John Richeson
Summary: Bovine Respiratory Disease (BRD) is a significant concern for the US beef industry, and this study investigates the role of Mycoplasma bovis in acute BRD. The findings suggest that M. bovis may influence the respiratory environment and increase the prevalence of Mannheimia haemolytica, a primary bacterial pathogen driving BRD.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Mauida F. Hasoon, Veronica M. Jarocki, Majed H. Mohammed, Steven P. Djordjevic, Hiu Ying Esther Yip, Mandi Carr, Aliakbar Khabiri, Ania Ahani Azari, Reza Amanollahi, Raziallah Jafari Jozani, Brodhi Carracher, Joanne Mollinger, Ania T. Deutscher, Farhid Hemmatzadeh, Darren J. Trott
Summary: Antimicrobial susceptibility of Australian Mycoplasma bovis isolates has not been reported. This study examined minimal inhibitory concentrations (MICs) of 12 antimicrobials against Australian M. bovis isolates and used whole genome sequencing to identify point mutations in target genes associated with high macrolide MICs. Most samples from bovine respiratory disease cases tested positive for M. bovis. The majority of isolates had low MICs for several antimicrobials, but a small proportion exhibited high MICs for macrolides and lincosamides. Whole genome sequencing revealed mutations in the 23S rRNA gene associated with macrolide resistance. Monitoring for emerging macrolide resistance in Australian M. bovis isolates is needed.
VETERINARY MICROBIOLOGY
(2023)
Article
Microbiology
Estelle Kanyala, Yassir Adam Shuaib, Norbert Georg Schwarz, Soenke Andres, Elvira Richter, Bernard Sawadogo, Mamadou Sawadogo, Minoungou Germaine, Ouattara Lassina, Sven Poppert, Hagen Frickmann
Summary: This study conducted at slaughterhouses in Burkina Faso found a prevalence of 2.7% for bovine tuberculosis (bTB) suggestive lesions in slaughtered cattle carcasses. The predominant causative agent was identified as M. bovis, with other mycobacteria species also detected. The study suggests the need for further research to investigate zoonotic transmission of mycobacteria in the region.
Review
Microbiology
Roger Dumke
Summary: This review summarizes the typing methods for Mycoplasma pneumoniae and Mycoplasma genitalium, including their application in different studies, and presents the current knowledge regarding the association of typing data with the clinical characteristics of infections.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Harish Menghwar, Tracy Prysliak, Jose Perez-Casal
Summary: The study genotyped 61 M. bovis strains isolated from cattle and bison in different provinces of Canada using MLST and MLVA, revealing multiple sequence types and genotype populations. These findings may aid in understanding the evolution of M. bovis and developing strain-specific or sequence type diagnostic tools.
VETERINARY MICROBIOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
G. Gioia, M. F. Addis, C. Santisteban, B. Gross, D. Nydam, A. S. Sipka, P. D. Virkler, R. D. Watters, M. Wieland, M. J. Zurakowski, P. Moroni
Summary: The predominant Mycoplasma species found in mastitic milk is Mycoplasma bovis, but other species are also present. Testing milk samples for mycoplasmas that can identify both the genus and the species is crucial.
JOURNAL OF DAIRY SCIENCE
(2021)
Correction
Multidisciplinary Sciences
Ana C. Reis, Rogerio Tenreiro, Teresa Albuquerque, Ana Botelho, Monica V. Cunha
Summary: The paper has been published with an amendment, which can be accessed through a link at the top of the paper.
SCIENTIFIC REPORTS
(2021)
Article
Veterinary Sciences
Hussam Askar, Huafang Hao, Xinmin Yan, Lina Ma, Shimei Lan, Yongsheng Liu, Shengli Chen, Yuefeng Chu
Summary: This study investigated the impact of M. bovis field strain 07801 on PBMC status in challenged and immunized cattle groups, revealing an increase in proliferative response but no significant effects on apoptosis. Levels of cytokines were significantly up-regulated in both groups, except for IL-4 and IL-18 which were down-regulated in the immunized group in the early stages post-M. bovis infection.
PAKISTAN VETERINARY JOURNAL
(2021)
Article
Veterinary Sciences
Robert F. Kelly, Lina Gonzalez Gordon, Nkongho F. Egbe, Emily J. Freeman, Stella Mazeri, Victor N. Ngwa, Vincent Tanya, Melissa Sander, Lucy Ndip, Adrian Muwonge, Kenton L. Morgan, Ian G. Handel, Barend M. de C. Bronsvoort
Summary: This study aims to explore the agreement and disagreement between the IFN-gamma assay and SCITT test in an African cattle population. The results show that there is a variation in the performance of the two tests, and factors such as age, gender, and co-infections are associated with the disagreement between the tests.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Multidisciplinary Sciences
Md Nazimul Islam, Mohammad Kamruzzaman Khan, Mohammad Ferdousur Rahman Khan, Polychronis Kostoulas, A. K. M. Anisur Rahman, Md Mahbub Alam
Summary: Bovine tuberculosis is endemic in Bangladesh with a true prevalence of 21.9% at the animal level and varying from 41.9% to 88.8% at the herd level in different regions. Risk factors for bTb include herd size, grazing status, breed of cows, and presence of cough symptoms. Surveillance and control programs should target crossbred cows that do not graze and show cough symptoms, while herds in specific regions like Mymensingh, Sadar, and Bhaluka need special attention. Utilizing Bayesian hierarchical true prevalence estimation can help identify high-risk areas for targeted intervention.