Article
Agriculture, Dairy & Animal Science
L. R. Larsen, P. H. Baker, K. M. Enger, L. E. Moraes, P. R. F. Adkins, J. A. Pempek, C. A. Zimmerly, S. M. Gauta, R. L. Bond, B. D. Enger
Summary: The study demonstrated that administration of internal teat sealants (ITS) in primigravid heifers reduced the prevalence of intramammary infections (IMI) at calving, regardless of whether ITS was given 75 or 35 days prepartum. Control quarters were more likely to be infected at calving compared to quarters treated with ITS. Early administration of ITS provided extended protection for the developing gland.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Pari H. Baker, Sheila K. Jacobi, R. Michael Akers, Benjamin D. Enger
Summary: Intramammary infections (IMI) in nonlactating dairy cattle can impair mammary growth and development and reduce future milk production. This study evaluated how IMI alter tissue structure in growing heifer mammary glands. The results indicate that IMI reduce mammary epithelial growth and alter mammary gland development, which may have adverse effects on milk production.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
L. R. Larsen, L. E. Moraes, B. D. Enger
Summary: Intramammary infections in primigravid dairy heifers can affect mammary growth and development, leading to reduced milk yield. This study suggests that mammary secretion somatic cell count and viscosity can be used as indicators of infection status in primigravid heifers.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Veterinary Sciences
Philipp Rueben, Martin tho Seeth, Anne Tellen, Volker Kroemker
Summary: The aim of this study was to identify risk factors associated with a high heifer mastitis rate and to determine whether the period before or after calving contains more risk factors. Both pre-partum and post-partum risk factors were identified, with post-partum factors being more significant. This highlights the importance of post-partum management in improving heifer udder health.
VETERINARY SCIENCES
(2023)
Article
Dentistry, Oral Surgery & Medicine
Alice Blufstein, Christian Behm, Barbara Kubin, Johannes Gahn, Andreas Moritz, Xiaohui Rausch-Fan, Oleh Andrukhov
Summary: This study reveals the immunomodulatory properties of GMSCs towards PMNs, with IL-1 beta enhancing their anti-apoptotic effects. However, GMSCs did not affect the ROS production of PMNs.
Article
Pathology
Aysha A. A. Aljawder, Joshua J. X. Li, Joanna K. M. Ng, Ronald C. K. Chan, Philip C. W. Lui, Ivan K. Poon, Julia Y. S. Tsang, Gary M. Tse
Summary: This study reviewed cases of IGM to assess histological parameters and clinical data. The cohort consisted of 79 cases, including 51 non-CNGM IGM and 28 CNGM. There were no significant differences in clinical or demographic data between the two groups, except for a younger age of presentation in CNGM. Most IGM cases resolved during the follow-up period, regardless of treatment. CNGM showed distinct histological features with more infiltrates of specific inflammatory cells.
Article
Medicine, General & Internal
Qurat Ul Ain Zahid, Nausheen Yaqoob, Nausheen Ferozuddin, Sheema H. Hasan
Summary: Granulomatous lobular mastitis is a rare inflammatory breast disease that can mimic malignancy. It typically occurs in parous or lactating women and can be caused by infection or autoimmune disorders. Cystic neutrophilic granulomatous mastitis is a subtype of granulomatous lobular mastitis that is associated with Gram-positive bacilli infection.
JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
(2022)
Article
Biochemistry & Molecular Biology
Zhangrui Cheng, Laura Buggiotti, Mazdak Salavati, Cinzia Marchitelli, Sergio Palma-Vera, Alistair Wylie, Haruko Takeda, Lijing Tang, Mark A. Crowe, D. Claire Wathes
Summary: This study compared the transcriptomic profiles in circulating leukocytes between healthy cows and those with naturally occurring subclinical or clinical mastitis, revealing more intensive changes attributed to clinical mastitis. Most of the differentially expressed genes were associated with cell killing and immune processes. Notably, many upregulated genes encoding antimicrobial peptides in clinical mastitis were not upregulated in subclinical mastitis, suggesting a key role in combating disease organisms.
MOLECULAR BIOLOGY REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Galina N. Semenkova, Nadezda Amaegberi, Alexandra G. Lisovskaya, Serge Pinchuk, Anna G. Poleshko, Oleg Shadyro
Summary: 2-Hexadecenal (2-HD) affects the functions of PMNLs by increasing ROS production at submicromolar concentrations and inducing apoptosis at higher concentrations. The modification of signal transduction pathways, such as the elevation of NADPH oxidase, MPO, and JNK-MAPK contributions, is associated with the increased ROS production. The induction of apoptosis is accompanied by an increase in cytoplasmic free Ca2+, a decrease in ROS production, a decline in mitochondrial potential, and cytoskeleton reorganization.
CELL BIOCHEMISTRY AND BIOPHYSICS
(2023)
Article
Agriculture, Dairy & Animal Science
Seung-Hwan Lee, Dooho Lee, Mingyung Lee, Seung-Heui Ryoo, Seongwon Seo, Inchul Choi
Summary: This study conducted a genome-wide association study on 40 Korean native beef cattle and identified 12 significant SNPs associated with services per conception (SPC) and their proximal genes. These SNPs were located in seven regions on three chromosomes and were involved in early embryo development and muscle cell differentiation.
ANIMAL BIOTECHNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Ankit Magotra, Y. C. Bangar, C. S. Patil, Pradeep Kamaldeep, Vikas Sindhu, Deepak Malik, Pradeep Chaudhary, Asha Rani Garg, Sandeep Kumar
Summary: The present study investigated the association between CXCR1 gene polymorphisms and clinical mastitis, reproductive disorders, and performance traits in Hardhenu cattle. A targeted SNP rs211042414 (C>T) in the CXCR1 gene was genotyped using PCR amplification and Bsa1 restriction enzyme digestion. Significant associations were found between the SNP and clinical mastitis occurrence. The CC genotype showed higher susceptibility to clinical mastitis and higher milk yields compared to CT and TT genotypes.
REPRODUCTION IN DOMESTIC ANIMALS
(2023)
Article
Agriculture, Dairy & Animal Science
Hannah N. Phillips, Ulrike S. Sorge, Bradley J. Heins
Summary: The period immediately following calving can be stressful for young dairy cows, as they need to adjust to the unfamiliar aspects of milking. Pre-calving teat sanitization and acclimation to the milking area can help improve post-calving milking behaviors and reduce the risk of bacterial mammary infections. Additionally, providing these preparations may promote a more positive human-animal relationship.
Article
Agriculture, Dairy & Animal Science
S. Magro, A. Costa, M. Santinello, M. De Marchi, M. Penasa
Summary: The milk differential somatic cell count (DSCC) has been proposed as a means to monitor udder health status (UHS) in dairy cows. The study analyzed milk test-day records of different cow breeds to identify factors affecting DSCC and SCC variability. Udder health-related traits (SCS and DSCC) were found to be useful in improving individual cow and herd udder health. The combination of SCS and DSCC is also useful in monitoring milk yield and composition.
Article
Agriculture, Dairy & Animal Science
Aarif Ali, Muneeb U. Rehman, Syed Mudasir Ahmad, Tabish Mehraj, Ishraq Hussain, Ahmed Nadeem, Manzoor Ur Rahman Mir, Showkat Ahmad Ganie
Summary: Dairy cattle with a high milk yield are susceptible to subclinical mastitis, and this study focused on the polymorphisms in the bovine transferrin gene for early detection and resistance. The sequencing results revealed nucleotide differences between susceptible cows and disease-free subjects, and in silico tools confirmed the impact on protein structure and function. Phylogenetic analysis showed close relations between the transferrin gene alleles and specific cattle breeds.
Article
Microbiology
Lisa C. Hennemann, Shantelle L. LaFayette, Julien K. Malet, Perrine Bortolotti, Tianxiao Yang, Geoffrey A. McKay, Daniel Houle, Danuta Radzioch, Simon Rousseau, Dao Nguyen
Summary: Loss-of-function lasR mutants of Pseudomonas aeruginosa induce increased levels of airway epithelial ICAM-1, leading to enhanced neutrophilic inflammation and exacerbating lung disease progression. This study sheds light on the intricate interplay between lasR mutants, LasR-regulated proteases, and airway epithelial ICAM-1 expression, revealing a new mechanism involved in the exaggerated inflammatory response induced by lasR mutants.
Article
Veterinary Sciences
Kimberley Stee, Mario Van Poucke, Luc Peelman, Mark Lowrie
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2020)
Article
Agriculture, Dairy & Animal Science
D. Valckenier, S. Piepers, A. De Visscher, S. De Vliegher
JOURNAL OF DAIRY SCIENCE
(2020)
Article
Reproductive Biology
Nuria Llamas Luceno, Daniel de Souza Ramos Angrimani, Luana de Cassia Bicudo, Katarzyna J. Szymanska, Mario Van Poucke, Kristel Demeyere, Evelyne Meyer, Luc Peelman, Erik Mullaart, Marleen L. W. J. Broekhuijse, Ann Van Soom
Article
Agriculture, Dairy & Animal Science
S. Piepers, I. Van Den Brulle, K. Mertens, S. De Vliegher
JOURNAL OF DAIRY SCIENCE
(2020)
Article
Agriculture, Dairy & Animal Science
F. N. Souza, M. G. Blagitz, C. F. Batista, P. Takano, R. G. Gargano, S. A. Diniz, M. X. Silva, J. A. Ferronatto, K. R. Santos, M. B. Heinemann, S. De Vliegher, A. M. M. P. Della Libera
JOURNAL OF DAIRY SCIENCE
(2020)
Article
Multidisciplinary Sciences
Miriam Ayuso, Joris Michiels, Sander Wuyts, Honglin Yan, Jeroen Degroote, Sarah Lebeer, Cindy Le Bourgot, Emmanuelle Apper, Maryam Majdeddin, Noemie Van Noten, Charlotte Vanden Hole, Steven Van Cruchten, Mario Van Poucke, Luc Peelman, Chris Van Ginneken
Article
Veterinary Sciences
Honglin Yan, Bing Yu, Jeroen Degroote, Thomas Spranghers, Noemie Van Noten, Maryam Majdeddin, Mario Van Poucke, Luc Peelman, Jo De Vrieze, Nico Boon, Ingrid Gielen, Stefaan De Smet, Daiwen Chen, Joris Michiels
BMC VETERINARY RESEARCH
(2020)
Article
Veterinary Sciences
Veronique Saey, Annelies Decloedt, Mario Van Poucke, Luc Peelman, Gunther van Loon, Katrien Vanderperren, Richard Ducatelle, Koen Chiers
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2020)
Article
Multidisciplinary Sciences
Jurriaan Hoekstra, Aldert L. Zomer, Victor P. M. G. Rutten, Lindert Benedictus, Arjan Stegeman, Mirlin P. Spaninks, Torben W. Bennedsgaard, Andrew Biggs, Sarne De Vliegher, Demetrio Herrera Mateo, Reglindis Huber-Schlenstedt, Jorgen Katholm, Peter Kovacs, Volker Kromker, Guillaume Lequeux, Paolo Moroni, Luis Pinho, Sebastian Smulski, Karlien Supr, Jantijn M. Swinkels, Mark A. Holmes, Theo J. G. M. Lam, Gerrit Koop
SCIENTIFIC REPORTS
(2020)
Article
Agriculture, Dairy & Animal Science
D. Valckenier, S. Piepers, Y. H. Schukken, A. De Visscher, F. Boyen, F. Haesebrouck, S. De Vliegher
Summary: The study found that IMI caused by Staphylococcus chromogenes had longer duration compared to IMI caused by other NAS species, with only a small percentage persisting for more than 2 days; Quarters with higher qSCC usually had IMI caused by major pathogens, followed by S. chromogenes and other NAS species.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
I Adriaens, I van den Brulle, L. D'Anvers, J. M. E. Statham, K. Geerinckx, S. De Vliegher, S. Piepers, B. Aernout
Summary: This study investigated the characteristics of milk yield dynamics during perturbations in dairy cows milked with an automated milking system. Results showed that most cows experienced multiple perturbations within the first 305 days after calving, with higher parity cows experiencing more severe perturbations. The method to characterize perturbations can be used for precision phenotyping purposes to understand cows' responses to challenges.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Elout Van Liefferinge, Noemie Van Noten, Jeroen Degroote, Gunther Vrolix, Mario Van Poucke, Luc Peelman, Chris Van Ginneken, Eugeni Roura, Joris Michiels
Article
Veterinary Sciences
David Claeys Bouuaert, Mario Van Poucke, Lina De Smet, Wim Verbeke, Dirk C. de Graaf, Luc Peelman
Summary: This study developed and validated high-throughput qPCR assays for discriminating eight single-nucleotide variants associated with suppressed mite reproduction in honey bees. Additional variants in the primer/probe binding sites were identified, and supplementary primers and probes were developed to ensure correct genotyping outcome. The availability of this assay allows genotyping for the suppressed mite reproduction trait and facilitates marker assisted selection in breeding programs.
BMC VETERINARY RESEARCH
(2021)
Article
Agriculture, Dairy & Animal Science
O. Bogado Pascottini, J. De Koster, F. Van Nieuwerburgh, M. Van Poucke, L. Peelman, V. Fievez, J. L. M. R. Leroy, G. Opsomer
Summary: This study aimed to evaluate the effect of normal versus overconditioning on the hepatic transcriptomic profile of dairy cows at the end of pregnancy. Results showed that overconditioned cows had increased fat mobilization, higher liver lipid content, and gene expression pattern biased towards inflammation.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Katerina Zadinova, Antonin Stratil, Mario Van Poucke, Luc J. Peelman, Jaroslav Citek, Monika Okrouhla, Nicole Lebedova, Kamila Pokorna, Michal Sprysl, Roman Stupka
Summary: This study investigated the effects of diets with different levels of dried Jerusalem artichoke on skatole levels and CYP2E1 mRNA expression in commercial crossbred pigs. The results showed that supplementation with Jerusalem artichoke led to lower skatole levels and higher CYP2E1 mRNA expression, suggesting a potential option to reduce skatole levels in adipose tissue of entire male pigs effectively.
ANNALS OF ANIMAL SCIENCE
(2021)