Review
Biochemistry & Molecular Biology
Antonella Smeriglio, Daniele Marcoccia, Marcella Denaro, Domenico Trombetta
Summary: This study reviews the literature of the last 10 years on the use of nutraceuticals in the prevention and treatment of inflammatory bowel diseases (IBD), mainly Ulcerative colitis (UC) and Crohn's disease (CD). Despite promising pre-clinical data, adequate nutraceutical treatment for these diseases is still far from being established and further studies are necessary to support this hypothesis.
CURRENT MEDICINAL CHEMISTRY
(2023)
Article
Surgery
Mary R. Kwaan, Yuqi Wu, Yang Ren, Sudha Xirasagar
Summary: Prompt intervention in cases of large bowel obstruction leads to shorter hospital stays and a higher likelihood of discharge to home, but does not affect mortality rates. Female, Black, and low-income patients are less likely to receive prompt intervention.
AMERICAN JOURNAL OF SURGERY
(2022)
Article
Orthopedics
Marcos Lopez-Vega, Julio Domenech-Fernandez, Salvador Peiro, Manuel Ridao-Lopez
Summary: This study investigated the use of arthroscopic meniscectomy in Spain from 2003 to 2018 and found an increase in the number of procedures performed during this period, particularly among older patients. The study showed that this increase is unnecessary, as previous research has shown that surgery is not superior to nonoperative treatment.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2023)
Article
Surgery
Rodrigo Capona, Tarek Hassab, Ipek Sapci, Alexandra Aiello, David Liska, Stefan Holubar, Amy L. Lightner, Scott R. Steele, Michael A. Valente
Summary: The study analyzed the surgical interventions and outcomes of patients with LBO, finding colorectal cancer to be the most common etiology and fecal diversion without resection to be the most common operation. Patients who had a resection and anastomosis with diverting loop ileostomy were most likely to undergo stoma reversal.
AMERICAN JOURNAL OF SURGERY
(2021)
Article
Gastroenterology & Hepatology
Yiyoung Kwon, Eun Sil Kim, Yon Ho Choe, Mi Jin Kim
Summary: After the introduction of infliximab, the relapse rate has decreased and the steroid-free period has increased in pediatric ulcerative colitis patients. The clinical course showed a different pattern from the IBSEN study.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Allergy
Ilkay Koca Kalkan, Hale Ates, Kurtulus Aksu, Selma Yesilkaya, Musa Topel, Dilek Cuhadar Ercelebi, Suleyman Turkyilmaz, Ali Oncul, Senay Demir
Summary: The study evaluated adherence to subcutaneous immunotherapy and found that dose modification and its frequency were the only factors related to nonadherence. The COVID-19 pandemic led to nearly a quarter of patients dropping out due to fear of infection, with short duration of AIT being the only predictor for drop-out.
WORLD ALLERGY ORGANIZATION JOURNAL
(2021)
Article
Communication
J. Baeker Bispo, A. Douyon, K. Ashad-Bishop, R. Balise, E. Kobetz
Summary: The emergence of COVID-19 has led to an increase in public trust in cancer information from charitable organizations, religious organizations, and doctors, but a decrease in trust among non-Hispanic Blacks in information from government health agencies and family and friends. Further studies are needed to assess if this decline in trust will negatively impact preventive care participation among non-Hispanic Blacks.
JOURNAL OF HEALTH COMMUNICATION
(2023)
Article
Environmental Sciences
Long Wang, Qianqian Zhang, Huiwei Wang, Dimitrios E. Alexakis
Summary: This study investigated the driving mechanisms of groundwater chemical evolution based on long-term hydrochemical data from 19 groundwater monitoring sites in rapidly urbanizing areas of Shijiazhuang, China. The results show that the concentrations of various chemical components in groundwater gradually increase with the acceleration of urbanization, especially NO3, exceeding the World Health Organization drinking water standard. The driving factors of groundwater chemical evolution differ at different urbanization stages, suggesting that future groundwater management should control agricultural fertilizers, strengthen supervision of groundwater extraction, and prohibit non-compliant sewage discharge.
Article
Biotechnology & Applied Microbiology
Caiguang Liu, Na Li, Shukai Zhan, Zhenyi Tian, Dongxuan Wu, Tong Li, Zhirong Zeng, Xiaojun Zhuang
Summary: The results of this meta-analysis demonstrate that biologics are more effective than non-biological treatments in preventing postoperative recurrence in patients with Crohn's disease, with anti-TNFα agents showing superiority in preventing endoscopic recurrence. Additionally, infliximab and adalimumab have similar efficacy in preventing postoperative recurrence.
EXPERT OPINION ON BIOLOGICAL THERAPY
(2021)
Review
Immunology
Eva Gonzalez Barca
Summary: Diffuse large B-cell lymphoma is an aggressive and biologically heterogeneous disease. Standard first-line therapy is R-CHOP, while salvage high-dose chemotherapy with autologous stem cell transplant is the standard second-line treatment. However, not all patients are eligible for these treatments, and IgG-like bispecific antibodies (BsAbs) have shown promising efficacy in B-cell lymphomas by targeting CD20 on B cells and engaging T cells via CD3. BsAbs have a favorable toxicity profile and are being studied in new trials to confirm their efficacy and explore their use in different lines of therapy or in combination with other drugs.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Urology & Nephrology
Karl H. Tully, Alexander P. Cole, Marieke J. Krimphove, David F. Friedlander, Matthew Mossanen, Peter Herzog, Joachim Noldus, Guru P. Sonpavde, Quoc-Dien Trinh
Summary: During the study period, there was a significant decrease in the utilization of radical cystectomy for T1HG bladder cancer patients, especially during the BCG shortage period. The majority of patients opted for local treatment. Further research on the impact of treatment pattern changes on high-grade NMIBC patients is necessary.
Review
Medicine, General & Internal
Celine R. Soriano, Charleston R. Powell, Michael V. Chiorean, Vlad V. Simianu
Summary: Specialized care is often required for the treatment of inflammatory bowel disease (IBD). While outpatient care has become more common, hospitalizations still play a significant role in healthcare utilization for a sizable proportion of IBD patients. The focus on IBD care at the population level includes the shift from inpatient to outpatient care, the balance between emergency and elective hospitalizations, regionalization of specialty care, and the contribution of surgery and endoscopy to hospitalized care.
WORLD JOURNAL OF CLINICAL CASES
(2021)
Article
Orthopedics
L. Reid Boyce Nichols
Summary: Limb length discrepancy is common in both pediatric and adult populations. Discrepancies less than 5 cm may lead to long-term morbidities, and recent literature suggests that even small discrepancies can contribute to pathologic changes such as pain, gait abnormalities, and osteoarthritis. Advances in magnetically controlled lengthening devices have increased accuracy and patient satisfaction, making it a viable option for treating discrepancies < 5 cm.
JOURNAL OF PEDIATRIC ORTHOPAEDICS
(2021)
Review
Psychology, Clinical
Christian Grov, Drew A. Westmoreland, Alexa B. D'Angelo, David W. Pantalone
Summary: The use of PrEP has a significant impact on sexuality, including enhancing sexual self-esteem, improving sexual pleasure, reducing sexual anxiety, and increasing sexual agency. However, research on PrEP, while abundant for GBMSM, remains insufficient for cisgender women and transgender populations.
JOURNAL OF SEX RESEARCH
(2021)
Article
Economics
Javad Esmailpour, Kayvan Aghabayk, Mohammad Aghajanzadeh, Chris De Gruyter
Summary: COVID-19 has affected passenger loyalty towards public transport, with perceptions of service quality improving but loyalty decreasing. The increased attractiveness of using private cars has been identified as the primary factor contributing to this decline.
TRANSPORTATION RESEARCH PART A-POLICY AND PRACTICE
(2022)
