Article
Nutrition & Dietetics
Eric Bartholomae, Jessica Knurick, Carol S. Johnston
Summary: A growing number of Americans are adopting vegetarian or vegan diets, raising concerns about sufficient protein intake. This study found that vegetarian participants had lower protein intake, lean body mass, serum creatinine, and handgrip strength compared to omnivorous participants. However, regardless of diet, serum creatinine concentrations correlated with lean body mass and strength in healthy adults.
FRONTIERS IN NUTRITION
(2022)
Article
Gastroenterology & Hepatology
Anika Varma, Jennifer Weinstein, Jamison Seabury, Spencer Rosero, Ellen Wagner, Christine Zizzi, Elizabeth Luebbe, Nuran Dilek, Michael McDermott, John Heatwole, Lawrence Saubermann, Larissa Temple, Scott Rogoff, Chad Heatwole
Summary: This study aimed to identify the most prevalent and impactful symptoms in patients with Crohn's disease (CD) and to determine the modifying factors associated with a higher disease burden in CD.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Geriatrics & Gerontology
Laetitia Lengele, N. A. Grande de Franca, Y. Rolland, S. Guyonnet, P. de Souto Barreto
Summary: Dietary patterns were found to have varying associations with body composition and physical performance based on age and sex. Men tended to have less healthy food intake across all age groups. Diets high in sugary foods, fast foods, and processed meat were linked to higher fat mass and lower strength in the study participants.
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
Article
Clinical Neurology
Rebecca J. Y. Abay, Laura S. Gold, Peggy M. Cawthon, James S. Andrews
Summary: Older adults with cognitive impairment, especially those with Alzheimer's disease and related dementias, are more likely to be hospitalized and experience hospital-associated disability. Sarcopenia, age-related declines in muscle mass and strength, may be a significant risk factor for hospital-associated disability.
ALZHEIMERS & DEMENTIA
(2022)
Article
Geriatrics & Gerontology
Shu Zhang, Rei Otsuka, Chikako Tange, Yukiko Nishita, Hiroshi Shimokata, Shosuke Satake, Hidenori Arai
Summary: The joint effect of BMI and GS is significant in predicting disability in community-dwelling older adults in Japan.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Multidisciplinary Sciences
Melissa J. Benton, Jefferson M. Spicher, Amy L. Silva-Smith
Summary: Among older adults, handgrip strength is commonly used as an indicator of frailty and sarcopenia. However, this study found that there is poor agreement between the two most frequently used handgrip dynamometers, indicating a lack of validity. Standardization and device-specific cutoff points are needed for accurate diagnosis.
Article
Surgery
Chelsia Gillis, Lauren Richer, Tanis R. Fenton, Leah Gramlich, Heather Keller, S. Nicole Culos-Reed, Tolulope T. Sajobi, Rashami Awasthi, Francesco Carli
Summary: This study examined the relationship between preoperative nutritional status and physical function, quality of life, and body composition in colorectal cancer patients. The results showed that malnourished patients had poorer physical function and quality of life. Male malnourished patients had lower body weight and body fat percentage, while females had higher variability.
Review
Immunology
Reza Yarani, Ali Shojaeian, Oana Palasca, Nadezhda T. Doncheva, Lars Juhl Jensen, Jan Gorodkin, Flemming Pociot
Summary: This review discusses the differential regulation of miRNAs in inflammatory bowel disease (IBD) and their potential diagnostic and therapeutic applications. Through literature curation and computational analysis, a consensus set of differentially expressed miRNAs in mucosal tissues was obtained. The role of these miRNAs and their potential targets in IBD are highlighted.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Geriatrics & Gerontology
James S. Andrews, Laura S. Gold, May J. Reed, Jose M. Garcia, Robyn L. McClelland, Annette L. Fitzpatrick, Catherine L. Hough, Peggy M. Cawthon, Ken E. Covinsky
Summary: The study found that lower grip strength before hospitalization may be an important risk factor for the development of ADL disability among older adults, while ALM and grip strength were not significantly associated with death.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Gastroenterology & Hepatology
Julien Kirchgesner, Rishi J. Desai, Maria C. Schneeweiss, Laurent Beaugerie, Sebastian Schneeweiss, Seoyoung C. Kim
Summary: Combination therapy with vedolizumab and thiopurines is associated with a lower risk of treatment failure compared to vedolizumab monotherapy in patients with CD, but the effect is less pronounced in UC.
Review
Nutrition & Dietetics
Meng Thiam Lim, Bernice Jiaqi Pan, Darel Wee Kiat Toh, Clarinda Nataria Sutanto, Jung Eun Kim
Summary: While animal protein appears to be more beneficial for increasing lean mass, particularly in younger adults, resistance exercise training does not seem to have an impact on the results.
Article
Gastroenterology & Hepatology
Tatsuki Noguchi, Soichiro Ishihara, Motoi Uchino, Hiroki Ikeuchi, Koji Okabayashi, Kitaro Futami, Shinji Tanaka, Hiroki Ohge, Hisashi Nagahara, Kazuhiro Watanabe, Michio Itabashi, Kinya Okamoto, Yoshiki Okita, Tsunekazu Mizushima, Yusuke Mizuuchi, Kazutaka Yamada, Yoshifumi Shimada, Yu Sato, Hideaki Kimura, Kenichi Takahashi, Koya Hida, Yusuke Kinugasa, Junji Okuda, Koji Daito, Fumikazu Koyama, Hideki Ueno, Takayuki Yamamoto, Tsunekazu Hanai, Atsuo Maemoto, Koji Oba, Yoichi Ajioka, Kenichi Sugihara
Summary: Patients with longstanding inflammatory bowel disease, such as ulcerative colitis and Crohn's disease, are at high risk of developing intestinal cancers. This study found significant differences between intestinal cancers associated with ulcerative colitis and Crohn's disease. Crohn's disease-associated cancers were diagnosed at more advanced stages, detected less frequently by surveillance, and had a poorer prognosis compared to those associated with ulcerative colitis.
JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Valentina Muollo, Toni Tatangelo, Laura Ghiotto, Valentina Cavedon, Chiara Milanese, Mauro Zamboni, Federico Schena, Andrea P. Rossi
Summary: This study investigated the association between handgrip strength and muscle function of the lower limbs, as well as predictors of appendicular lean mass index in older adults with obesity. Results showed that handgrip strength was weakly associated with lower limbs muscle function and physical performance, while BMI was a significant predictor for ALMI in both genders. In the group of men, markers related to strength and power of the lower limbs were found to better explain variations in ALMI compared to handgrip strength.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Nutrition & Dietetics
Laurent Beghin, Jeremy Vanhelst, Elodie Drumez, Mathilde Kersting, Denes Molnar, Anthony Kafatos, Stefaan De Henauwn, Kurt Wildhalm, Eva Karaglani, Luis A. Moreno, Frederic Gottrand
Summary: The study found that birth weight and breastfeeding duration have different effects on physical fitness components, with birth weight positively influencing muscular power development, while breastfeeding duration positively influences muscular explosivity.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Medicine, General & Internal
Geert D'Haens, Remo Panaccione, Filip Baert, Peter Bossuyt, Jean-Frederic Colombel, Silvio Danese, Marla Dubinsky, Brian G. Feagan, Tadakazu Hisamatsu, Allen Lim, James O. Lindsay, Edward V. Loftus, Julian Panes, Laurent Peyrin-Biroulet, Zhihua Ran, David T. Rubin, William J. Sandborn, Stefan Schreiber, Ezequiel Neimark, Alexandra Song, Kristina Kligys, Yinuo Pang, Valerie Pivorunas, Sofie Berg, W. Rachel Duan, Bidan Huang, Jasmina Kalabic, Xiaomei Liao, Anne Robinson, Kori Wallace, Marc Ferrante
Summary: This study evaluated the safety and efficacy of Risankizumab as induction therapy for patients with moderately to severely active Crohn's disease. The results showed that Risankizumab had a significant clinical impact and was well tolerated in treating Crohn's disease.