Review
Medicine, General & Internal
Kaja Skowronek, Wojciech Labus, Rafal Stojko, Diana Kitala, Marcin Sadlocha, Agnieszka Drosdzol-Cop
Summary: The study emphasizes on the benefits of using acellular dermal matrix (ADM) in urogynaecological and reconstructive surgery over traditional methods with higher durability and effectiveness without typical side effects of synthetic materials. Although ADM is not widely used in clinical practice, its potential is promising, prompting the need for more research to compare different surgical methods.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Surgery
Carter J. Boyd, Jonathan M. Bekisz, Mihye Choi, Nolan S. Karp
Summary: Acellular dermal matrices, derived from human tissue, have significantly advanced breast reconstruction in surgery. However, the U.S. Food and Drug Administration has stated that these matrices are not approved for use in breast reconstruction, leading to the classification of their use as off-label.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Article
Surgery
Nicole Gherlone, Patrick Sowa, Maria Osipova, Robert Walton
Summary: This article reports a unique case in which Acellular Dermal Matrix (ADM) used in central pillar neonipple reconstruction mimicked a retroareolar mass. The patient underwent delayed nipple reconstruction using ADM and a screening mammogram detected a new mass, which turned out to be partially incorporated ADM. To avoid misinterpretation of ADM in nipple reconstruction, the use of radiopaque markers on the implant could be helpful.
ANNALS OF PLASTIC SURGERY
(2022)
Article
Surgery
Miriam du Plessis, Patrick S. Cottler, Chris A. Campbell
Summary: The use of acellular dermal matrix in breast reconstruction has shown improvement in clinical safety outcomes and potential benefits such as decreased complications and accelerated wound healing. However, more long-term clinical data are needed to understand its performance and safety.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Review
Otorhinolaryngology
Shivam Patel, Kasra Ziai, Jessyka G. Lighthall, Scott G. Walen
Summary: Acellular dermal matrices (ADMs) are composed of a basement membrane and acellular dermal layer of collagen, providing a platform for mucosal epithelization and neovascularization. They support adequate wound healing and soft tissue repairs, reducing the need for autologous tissue grafts and minimizing donor site morbidity. The literature on ADMs in head and neck reconstruction for cosmetic and reconstructive purposes is rapidly evolving.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2022)
Article
Surgery
Milan M. Hirpara, Robert Craig Clark, Elise Hogan, Riley Dean, Chris M. Reid
Summary: This study demonstrates a significant correlation between ADM-related publication, industry funding, funding disclosure, and public interest. These findings emphasize the importance of objectivity in plastic surgery and the need for education on such relationships.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2023)
Article
Surgery
Siwei Qu, Jiarong Yi, Zheng Chen, Jianda Zhou
Summary: The study combined acellular dermal matrix (ADM) with autologous dermal cells as a filling material, and found that the ratio of 50%:50% demonstrated the best filling effect, reducing infiltration of inflammatory cells, increasing vascular density, and being more effectively absorbed.
AESTHETIC PLASTIC SURGERY
(2021)
Article
Chemistry, Multidisciplinary
Young-Joo Lee, Suhail K. Kanchwala, Hyesung Cho, Jason Christopher Jolly, Eric Jablonka, Michael Tanis, Randall D. Kamien, Shu Yang
Summary: To achieve successful and aesthetic breast reconstruction for breast cancer survivors, acellular dermal matrices (ADMs) are commonly used. However, traditional ADM sheets cannot fully cover breast implants without wrinkles. In this study, a kirigami strategy is proposed to cut ADM sheets with controlled stretchability, curvature, and elasticity. This approach allows for better conformity and support for reconstructed breasts, offering potential benefits in terms of outcomes and cost efficiency.
ADVANCED MATERIALS
(2023)
Article
Surgery
Justin M. Broyles, Eric C. Liao, John Kim, Jonathan Heistein, Mark Sisco, Nolan Karp, Frank H. Lau, Yoon S. Chun
Summary: This study is the first prospective, multicenter, randomized controlled clinical trial to compare human acellular dermal matrix-related complications of the two most commonly used human acellular dermal matrices in implant-based breast reconstruction. The results showed no significant difference in matrix-related complication rates between FlexHD Pliable and AlloDerm RTU.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2021)
Article
Ophthalmology
B. Monjanel, S. Baillif, J. Lagier, L. Gastaud, G. Poissonnet, Arnaud Martel
Summary: This study reported the experience of using artificial dermis grafts for orbital socket reconstruction following orbital exenteration. Results showed that using artificial dermis grafts alone or with regional flaps is a viable surgical procedure, reducing surgical morbidity and hospital stay, while preoperative and postoperative radiotherapy does not seem to delay socket healing.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2021)
Article
Dermatology
Je Yeon Byeon, Yong Seon Hwang, Hwan Jun Choi, Jun Hyuk Kim, Da Woon Lee
Summary: Micronized acellular dermal matrix (ADM) treatment has shown positive results in treating diabetic foot ulcers (DFU) that have invaded ligaments or bones, with a low recurrence rate. Close follow-up of weight bearing areas allows for early identification and treatment of recurrence.
INTERNATIONAL WOUND JOURNAL
(2023)
Review
Biochemistry & Molecular Biology
Marcin Gierek, Wojciech Labus, Diana Kitala, Andrzej Lorek, Gabriela Ochala-Gierek, Karolina Mikus Zagorska, Dariusz Waniczek, Karol Szyluk, Pawel Niemiec
Summary: Reconstructive surgery often deals with large tissue defects and requires materials that are both immunogenic but offer tissue filling. ADM, an acellular dermal matrix, is a commonly used biological collagen matrix without immunogenicity. This literature review examines the use of human ADM in reconstructive surgery across different fields, emphasizing the need for further research in this area.
Article
Surgery
Ivan R. Almeida, Adriana C. Gonqalves, Fernanda B. Correa, Julio C. D. Castro, Elaine C. O. Guirro, Jayme A. Farina Jr, Pedro S. Coltro
Summary: The aim of this study was to compare clinical and biomechanical features of scars resulting from the treatment of burn contractures using different acellular dermal matrices. The results suggest that there is no significant difference in the quality of the scar when using acellular dermal matrices compared to only split-thickness skin graft.
Review
Dentistry, Oral Surgery & Medicine
G. Romano, J. Bouaoud, A. Moya-Plana, N. Benmoussa, J. -F. Honart, N. Leymarie
Summary: The study compared the use of Integra dermal regeneration template in scalp reconstruction after tumor resection by analyzing literature and a series of 20 patients. Results showed that in large scalp full thickness defects after cancer resection, DRT appears to be a suitable reconstruction option for patients with comorbidities and aggressive tumors. This technique allows immediate coverage of the calvarium with short operative time and prevents healing delay, while maintaining oncologic follow-up and facilitating the diagnosis of cancer recurrences.
JOURNAL OF STOMATOLOGY ORAL AND MAXILLOFACIAL SURGERY
(2021)
Article
Medicine, General & Internal
Jeongshin An, Hyungju Kwon, Woosung Lim, Byung-In Moon, Nam Sun Paik
Summary: The study introduces the use of ADM in breast reconstruction during BCS, targeting patients with minor to severe defects post-operation. Results show that ADM can quickly correct breast shape after conventional BCS surgery, with pellet-type ADM creating a breast shape similar to pre-surgery. Despite the longer surgical time, the use of ADM in breast reconstruction proves to be effective in improving shape with minor complications.
JOURNAL OF CLINICAL MEDICINE
(2021)
